Biography
Orit Rozenblatt-Rosen, PhD, is Head of the Cell and Tissue Genomics (CTG) Department at Genentech. CTG aims to develop and apply high resolution methods to characterize cells and tissues to accelerate scientific discovery and help identify targets and next-generation biomarkers for precision medicine treatments for patients. Orit is a pioneer in single-cell genomics technologies and their application to tissues in order to better understand health and disease. Previously, she was the Scientific Director of the Klarman Cell Observatory at the Broad Institute of MIT and Harvard, where she focused on deciphering cellular and tissue circuits. She also co-chairs the standards and technology working group for the Human Cell Atlas consortium.

Biography
Isaac Kohane is the inaugural chair of Harvard Medical Schools Department of Biomedical Informatics, whose mission is to develop the methods, tools and infrastructure required for a new generation of scientists and care providers to move biomedicine rapidly forward by taking advantage of the insight and precision offered by big data. Kohane develops computational techniques to address disease at multiple scales, from whole health care systems to the functional genomics of neurodevelopment. He has worked on AI applications in medicine since the 1990s, including automated ventilator control, pediatric growth monitoring, detection of domestic abuse, diagnosing autism and assisting clinicians using whole genome sequence and clinical histories to diagnose rare disease patients. He is the inaugural Editor-in-Chief of NEJM AI and co-author of a recent book The AI Revolution in Medicine." He is a member of the National Academy of Medicine, the American Society for Clinical Investigation and the American College of Medical Informatics.

Biography
Dr. Christopher Longhurst's work has resulted in successful initiatives, including the development and implementation of predictive analytics tools that have transformed clinical decision-making. Passionate about transforming healthcare through innovation, Dr. Longhurst is also the visionary leader at the helm of the Joan Irwin Jacobs Center for Health Innovation. With a rich background in medicine and informatics, he spearheads groundbreaking initiatives that drive positive change in the digital healthcare landscape, ultimately helping to improve the patient experience.As an advocate for digital health on a broader scale, he has contributed his expertise to industry forums, collaborated with policymakers to shape healthcare legislation, and mentored emerging leaders in the field of digital health. He has authored over 100 peer-reviewed publications and book chapters in the fields of informatics, clinical decision support, and predictive analytics.

Biography
Michael A. Pfeffer, MD, FACP serves as Chief Information Officer and Associate Dean for Stanford Health Care and Stanford University School of Medicine. Michael oversees Technology and Digital Solutions (TDS), responsible for providing world class technology solutions to Stanford Health Care and School of Medicine, enabling new opportunities for groundbreaking research, teaching, and compassionate care across two hospitals and over 150 clinics. TDS supports Stanford Medicines mission to improve human health through discovery and care and strategic priorities to be value focused, digitally driven, and uniquely Stanford.Michael is a Clinical Professor in the Department of Medicine and Division of Hospital Medicine with a joint appointment in the center for Biomedical Research (BMIR) in Stanford University School of Medicine.

Biography
Chero serves as a System Vice President and Chief Information Digital Officer for the UW Health System. In his role, he serves a talented team of technology professionals and provides strategic direction and leadership for IT and co leads the Digital program in alignment with the mission and goals of UW Health. He also co-leads Workforce Strategy for the enterprise.Prior to UW Health , he worked at BJC Healthcare in St. Louis, where he served in a variety of leadership roles including Vice President for Business Relationship Management to deliver maximum value through technical and digital initiatives, co-led an enterprise-wide EMR initiative and led IT strategic planning for St. Louis Childrens Hospital. He has also worked in various other industries including finance, telecom and transportation.Chero received his dual masters degrees from Webster University and is an alumni of Columbia University, New York.

Biography
Brian is a global expert in pharmacoepidemiology and real-world data (RWD), with over 25 years of experience in industry and academia. At Amgen, he leads a team of over 150 professionalsincluding epidemiologists, biostatisticians, and data scientistsfocused on generating high-quality real-world evidence (RWE) to inform healthcare decision-making and support patient care. His team has conducted research across multiple countries, addressing drug safety, effectiveness, supporting regulatory approvals and post-marketing safety commitments, and describing disease burden and unmet need.Brian oversaw the development of Amgen's global RWD platform, housing data on more than 350 million lives, and successfully integrated the FDA Sentinel System to enhance safety surveillance efforts. He is an Adjunct Professor of Epidemiology at UCLA and has authored over 90 peer-reviewed publications on pharmacoepidemiology, disease epidemiology, and advanced methods for controlling confounding in drug safety research.

Talk
Accelerating Drug Development with Real-World Evidence and AI: Amgen's Journey

Biography
With extensive experience and achievements in health care information technology, Tanya leads the Stanford Childrens digital transformation and technology-driven initiatives. Overseeing an award-winning team, she will create enterprise resource planning systems, drive operational excellence, and spearhead strategic planning.She previously served as the Senior Vice President and Chief Information Officer at LCMC Health in New Orleans, Louisiana and the Vice President and Chief Information Officer at Greater Baltimore Medical Center in Baltimore, Maryland, and Chief Information Officer at HSHS Eastern WI Division in Green Bay, Wisconsin.Tanya holds a Master of Science in medical informatics from Milwaukee School of EngineeringMedical College of Wisconsin and a Bachelor of Science in health information administration.

Biography
William K. Oh, M.D., is currently the Director of Precision Medicine at Yale Cancer Center and a Professor of Medicine (Medical Oncology) at Yale School of Medicine, roles he assumed in October 2024. As part of a newer initiative at Yale, he is focused on building a cohesive program in precision cancer medicine that integrates basic and translational science, clinical trials, and Smilow Cancer Hospital’s Precision Medicine Tumor Board. A central goal of his work is to increase the routine use of molecular and genetic testing for all cancer patients to improve outcomes. Dr. Oh is also dedicated to delivering multidisciplinary care for prostate cancer patients, a priority he has maintained for over 25 years. He has been recognized as a Top Doctor by Castle Connolly, New York Magazine, and Super Doctors. Additionally, he continues his commitment to teaching and advancing research in the field. Previously, Dr. Oh was a Clinical Professor of Medicine at Icahn School of Medicine. He is an internationally recognized medical oncologist with extensive experience in clinical and translational research, holding leadership roles in both academia and industry. He has authored more than 350 articles, reviews, books, and book chapters related to genitourinary cancers. Dr. Oh has conducted numerous clinical cancer trials and served in key invited roles for ASCO, ACS, and AUA. He has also held the position of Chief Medical Officer for Sema4, a genomics and health intelligence company, as well as the Prostate Cancer Foundation.

Biography
Kiran Mysore is the Chief Data Analytics Officer at Sutter Health, a leading not-for-profit healthcare network in America. With over 25 years of experience, Kiran has been instrumental in driving digital transformation and leveraging data and AI to generate business value across various sectors, including healthcare, technology, and consulting.Before joining Sutter Health in September 2023, Kiran held significant roles at prestigious organizations such as Medtronic, GE, Apple, and St. Jude Medical. His expertise includes optimizing operations, developing real-time insights, and modernizing technology infrastructures. Known for his commitment to fostering data-driven cultures and championing diversity and ethical practices in data and AI, Kiran ensures that data insights are accessible and impactful at all organizational levels.Kirans leadership at Sutter Health focuses on making data and insights meaningful to improve healthcare outcomes, operational efficiency, and patient care. His work exemplifies the transformative power of technology in advancing healthcare.

Biography
Isaac Kohane is the inaugural chair of Harvard Medical Schools Department of Biomedical Informatics, whose mission is to develop the methods, tools and infrastructure required for a new generation of scientists and care providers to move biomedicine rapidly forward by taking advantage of the insight and precision offered by big data. Kohane develops computational techniques to address disease at multiple scales, from whole health care systems to the functional genomics of neurodevelopment. He has worked on AI applications in medicine since the 1990s, including automated ventilator control, pediatric growth monitoring, detection of domestic abuse, diagnosing autism and assisting clinicians using whole genome sequence and clinical histories to diagnose rare disease patients. He is the inaugural Editor-in-Chief of NEJM AI and co-author of a recent book The AI Revolution in Medicine." He is a member of the National Academy of Medicine, the American Society for Clinical Investigation and the American College of Medical Informatics.

Biography
Charles Jaffe is the CEO of HL7 International. He completed his medical training at Johns Hopkins and Duke Universities and postdoctoral training at NIH and the Lombardi Cancer Center. He served in various academic positions in the Departments of Medicine and in the School of Engineering. Previously, he was the Senior Global Strategist at Intel, led a national research consortium, found a consultancy for research informatics, served as the VP of Medical Informatics at AstraZeneca, and the VP of Life Sciences at SAIC. He was the contributing editor for several journals and has published on clinical research, informatics, and healthcare policy.

Talk
In this session, we can explore how AI and interoperability standards (like HL7 and FHIR) ensure secure, trustworthy, and reliable data in healthcare. Well focus on practical, real-world examples of how AI is transforming RWE and patient care while also addressing the risks of AI misuse, such as the example you mentioned. The session would also feature discussions on the latest regulatory and policy efforts to mitigate risks related to AI and data integrity.

Biography
Erik leads Demand Discovery Group (DDG), a company creation fund that puts Deliberate Innovation to work originating and developing startups. DDG focuses on software and AI for healthcare, biotech, cybersecurity, and cloud infrastructure.Prior, Erik built and led the data science, machine learning, and software engineering organization at Prometheus Biosciences (acquired by Merck for $10.8B), evaluated investments at Takeda's venture capital fund, and completed postdoctoral training at MIT, Massachusetts General Hospital, and the Broad Institute. Erik trained as a physician-engineer.

Biography
Dr. Christopher Longhurst's work has resulted in successful initiatives, including the development and implementation of predictive analytics tools that have transformed clinical decision-making. Passionate about transforming healthcare through innovation, Dr. Longhurst is also the visionary leader at the helm of the Joan Irwin Jacobs Center for Health Innovation. With a rich background in medicine and informatics, he spearheads groundbreaking initiatives that drive positive change in the digital healthcare landscape, ultimately helping to improve the patient experience.As an advocate for digital health on a broader scale, he has contributed his expertise to industry forums, collaborated with policymakers to shape healthcare legislation, and mentored emerging leaders in the field of digital health. He has authored over 100 peer-reviewed publications and book chapters in the fields of informatics, clinical decision support, and predictive analytics.

Biography
Dr. David Bray is a Distinguished Fellow and Co-Chair of the Loomis Innovation Council at the Stimson Center. With 30 years of experience, he has held various leadership roles in government, business, and tech. Dr. Bray is recognized for his expertise in AI, data, and emerging technologies. He has worked with U.S. Special Operations, led bioterrorism preparedness efforts, and directed multiple national initiatives on technology and security. He holds a PhD from Emory University and has held postdoctoral positions at MIT and Harvard.

Biography
John's work aims to improve research methods and practices and to enhance approaches to integrating information and generating reliable evidence. Science is the best thing that can happen to humans, but doing research is like swimming in an ocean at night. Science thrives in darkness. Born in New York City (1965), raised in Athens. Valedictorian (1984), Athens College; National Award, Greek Mathematical Society (1984); MD (top rank of medical school class) from National University of Athens (1990); also received DSc in biopathology from same institution. Trained at Harvard and Tufts (internal medicine, Infectious diseases), then held positions at NIH, Johns Hopkins, Tufts. Chaired the Department of Hygiene and Epidemiology, University of Ioannina Medical School (1999-2010) while also holding adjunct professor positions at Harvard, Tufts, and Imperial College. Moved to Stanford in 2010, initially as DirectorC.F. Rehnborg Chair at Stanford Prevention Research Center, then diversified with appointments in 4 departments and membership in 8 centersinstitutes at Stanford. Launched the PhD program in Epidemiology Clinical Research and the MS program in Community Health Prevention Research. Launched METRICS in 2014. NCINIH Senior Advisor on Knowledge Integration (2012-6). President (2023-4), Association of American Physicians. President, Society for Research Synthesis Methodology. Editorial board member of many leading journals (including PLoS Medicine, Lancet, Annals of Internal Medicine, JNCI, many others) and Editor-in-Chief of European Journal of Clinical Investigation (2010-2019). Delivered 700 invited and honorary lectures. Recipient of many awards (e.g. European Award for Excellence in Clinical Science 2007, Medal for Distinguished Service, Teachers College, Columbia U 2015, Chanchlani Global Health Award 2017, Epiphany Science Courage Award 2018, Einstein fellow 2018, Gordon award 2019, Albert Stuyvenberg Medal (2021), Harwood Prize 2022). Inducted in Association of American Physicians (2009), European Academy of Cancer Sciences (2010) American Epidemiological Society (2015), European Academy of Sciences and Arts (2015), National Academy of Medicine (2018), Accademia delle Scienze (Bologna) (2021). Honorary titles from FORTH (2014) and Ioannina (2015), honorary doctorates from Rotterdam (2015), Athens (2017), Tilburg (2019), Edinburgh (2021), Thessaloniki (2023), McMaster (ceremony 112024). Multiple honorary lectureshipsvisiting professorships (Caltech, Oxford, LSHTM, Yale, U Utah, U Conn, UC Davis, U Penn, Wash U St. Louis, NIH, Cedars-Sinai among others). The PLoS Medicine paper on Why most published research findings are false is the most-accessed article in the history of Public Library of Science (3 million hits). Author of 9 literary books, three of them shortlisted for best book of the year Anagnostis awards in Greece. Latest book (in English, published in 2022) is 2 books hyperlinked to each other. Brave Thinker scientist for 2010 per Atlantic, may be one of the most influential scientists alive. Highly Cited Researcher (Clarivate) in Clinical Medicine, Social Sciences and PsychiatryPsychology. h=259 (Google Scholar), current citation rate: 6,000 new citations per month (among the 6 scientists worldwide who are currently the most commonly cited). When contrasted against my vast ignorance, these values offer excellent proof that citation metrics can be horribly unreliable. I have no personal social media accounts - I admire people who can outpour their error-free wisdom in them, but I make a lot of errors, I need to revisit my writings multiple times before publishing, and I see no reason to make a fool of myself more frequently than it is sadly unavoidable. I consider myself privileged to have learned and to continue to learn from interactions with students and young scientists (of all ages) from all over the world and I love to be constantly reminded that I know next to nothing.

Biography
Dr. Don Rucker is Chief Strategy Officer at 1upHealth which provides scalable serverless FHIR data pipelines. He served as the National Coordinator at ONC where he led writing the 21st Century Cures Act Interoperability Rule giving patient apps access to their EHR data. He pioneered the Bulk FHIR standard which enables EHR big data. He co-developed the worlds first Windows-based EHR. Dr. Rucker reformed physician CPT4 documentation for 500 million US physician notes a year. He has practiced emergency medicine for 30 years. He is board certified in emergency medicine, internal medicine and clinical informatics. He holds an AB from Harvard, an MD from UPenn and MS and MBA from Stanford.

Biography
As an investor at Khosla Ventures, Jun focuses on long horizon technologies with applications in healthcare and biotech.He has spent over 10 years to bench and clinical research in areas such as immuno-oncology, microfluidics, iPSCs, rare diseases, and clinical trials. His research has generated numerous peer-reviewed publications and has been funded by many university awards as well as NIH research fellowships (IRTA and MRSP).Previously, Jun worked for Oshi Health and Octant Bio in business development and new product opportunity roles. While pursuing his medical degree at the University of Pennsylvania, he cofounded biotech pre-accelerator, Bio Launch (now Nucleate Philly), to move innovative ideas from academic labs to market. He later tied these operational experiences together at an early-stage VC firm, AlleyCorp, where he worked on incubations and healthcare investing.He obtained an M.D. from the University of Pennsylvania and a bachelors degree in chemical and biomolecular engineering from Johns Hopkins University.

Biography
Christopher P. Boone, PhD is an accomplished global executive, strategist, social scientist, and data technologist with a passion for reinventing and transforming healthcare and life sciences companies utilizing enterprise data analytics capabilities to drive value creation. Chris has a career long history as a dynamic, innovative thought leader and a public voice on the power of real world evidence, health informatics, and enterprise data analytics, and its ability to radically transform the global health care system into a learning health care system.

Biography
Stan Huff, MD, is our Chief Medical Informatics Officer at Graphite Health. Beginning in high school, Stan was fascinated by the potential of intelligent computer programs to revolutionize the practice of medicine. It may seem like a mighty goal for a young teenager but Stan was tenacious and utilized his magnificent balancing skills to ride unicycles, captain the football team, and win both a state championship for wrestling and a best legs contest, so you can imagine that the dream to revolutionize medicine was well within that youngsters grasp.Upon entering the real world, Stan focused his sights on medicine, receiving a BS in Chemistry from Brigham Young University and an MD from the University of Utah, where he would later teach biomedical informatics and oversee post-graduate student research. After a year of internal medicine residency training at the University of New Mexico in Albuquerque, Stan completed his residency in clinical pathology at the University of Utah. He then worked for two years at ATT Bell Laboratories in Columbus, Ohio, and since that time, he has held various positions at Intermountain Healthcare and the University of Utah.Today, Stan holds the position of Chief Medical Informatics Officer at Intermountain Healthcare and is a professor in biomedical informatics at the University of Utah School of Medicine in Salt Lake City, Utah.A primary focus of Stans career has been developing the language of digital medical data. He specializes in standardizing the representation of medical data and information in coded and structured form so that it can be processed algorithmically by computers. Stan was an early participant in the UMLS (Unified Medical Language System) contracts and has worked in medical terminology and database architecture for the past 30 years. He even teaches a course in medical vocabulary and data exchange standards at the University of Utah.When Stan isnt revolutionizing medicine, he likes to run marathons and travel the world. He is a fellow of the American College of Medical Informatics, a co-chair of the LOINC Committee, and a co-chair of the HL7 Clinical Information Modeling Initiative (CIMI). He is also the chair of Logica (formerly the Healthcare Services Platform Consortium (HSPC)) and the chair of the FHIR Foundation. Formerly, he was a member of the ONC HIT Standards Committee, a member of the National Committee on Vital and Health Statistics, a member of the Lister Hill Center Board of Scientific Counselors, and a two-time chair of Health Level Seven (HL7).

Biography
William K. Oh, M.D., is currently the Director of Precision Medicine at Yale Cancer Center and a Professor of Medicine (Medical Oncology) at Yale School of Medicine, roles he assumed in October 2024. As part of a newer initiative at Yale, he is focused on building a cohesive program in precision cancer medicine that integrates basic and translational science, clinical trials, and Smilow Cancer Hospital’s Precision Medicine Tumor Board. A central goal of his work is to increase the routine use of molecular and genetic testing for all cancer patients to improve outcomes. Dr. Oh is also dedicated to delivering multidisciplinary care for prostate cancer patients, a priority he has maintained for over 25 years. He has been recognized as a Top Doctor by Castle Connolly, New York Magazine, and Super Doctors. Additionally, he continues his commitment to teaching and advancing research in the field. Previously, Dr. Oh was a Clinical Professor of Medicine at Icahn School of Medicine. He is an internationally recognized medical oncologist with extensive experience in clinical and translational research, holding leadership roles in both academia and industry. He has authored more than 350 articles, reviews, books, and book chapters related to genitourinary cancers. Dr. Oh has conducted numerous clinical cancer trials and served in key invited roles for ASCO, ACS, and AUA. He has also held the position of Chief Medical Officer for Sema4, a genomics and health intelligence company, as well as the Prostate Cancer Foundation.

Biography
Brandon Allgood is a serial entrepreneur and researcher focused on applying machine learning (ML) and large-scale computational methods to improve human health. As the Chief Data Officer at Parabilis Medicines, he spearheads the integration of data science and engineering within the Helicon discovery and development framework. Alongside his role at Parabilis Medicines, Brandon imparts his knowledge of machine learning as an instructor at UC Berkeley and contributes his expertise as a scientific advisor to numerous biotech and tech entities. Brandon previously helped build three companies, Valo Health, Numerate, and Pharmix, at the forefront of applying modern ML and computational methods to drug discovery and development in diverse subfields, including chemistry, biology, clinical trials and real-world health data. Brandon has authored scientific publications in astrophysics, solid-state physics, computational biology and chemistry, and business. He is also founder and former executive chair of the Alliance for AI in Healthcare (AAIH).

Biography
Julian Hong is a radiation oncologist and informaticist. He specializes in the treatment of genitourinary malignancies such as prostate cancer. His research program focuses on the development and implementation of computational tools to provide personalized, precision cancer care for patients. His group combines clinical domain knowledge with computational expertise to generate insights from real world data, develop actionable artificial intelligence-based tools, and evaluate the benefit of these advances in patient care. He led one of the first randomized controlled studies of machine learning, successfully implementing machine learning-directed clinical evaluations to reduce emergency visits and hospitalizations during cancer radiotherapy.Dr. Hongs research has been published in high-impact, peer-reviewed journals such as the Journal of Clinical Oncology and JAMA Oncology. He has received awards including the Radiation Oncology Institute Publication Award, Bio-IT World Innovative Practices Award, and Symposium on Artificial Intelligence for Learning Health Systems New England Journal of Medicine Travel Award.

Biography
Dr. Riskin is an expert in healthcare artificial intelligence and successful serial entrepreneur. Products he has developed and commercialized benefit millions of patients annually. He has spoken on medical technology at FDA, NASA, DARPA, NSF, NIH, and CMS. His contributions have been featured in Forbes, The Wall Street Journal, and other leading media. He served on the Obama and Biden Healthcare Policy Committees, testified before Congress on the 21st Century Cures Initiative, and serves as a Congressional appointee of the US Health IT Advisory Committee. Dr. Riskin holds a MD, MBA, and four board certifications including surgery, critical care, palliative care, and clinical informatics. He trained at MIT, Stanford University, and University of California.

Biography
Jennifer Webster is the Head of Evidence Generation Platforms Partnerships at Pfizer, leading efforts in real-world data (RWD) partnerships, evidence generation systems, and RWEID innovation. She has a strong background in data analysis and healthcare analytics, previously holding roles at Kaiser Permanente, Integra Connect, and Qualcomm. Jennifer holds a BA in Chemistry from Bryn Mawr College and studied statistics at Texas AM University. Her work focuses on integrating real-world evidence into healthcare decision-making and drug development.

Biography
Dr. Michiel Niesen serves as the Senior Director of Biomedical Research at Nference, a biomedical A.I. company. Dr. Niesen's team transforms complex EHR data into actionable insights for developing better drugs and diagnostics, using Nference's proprietary de-identified clinical data platform, in partnership with leading healthcare systems and biopharma companies. Dr. Michiel Niesen completed his PhD from Caltech and postdoc from MIT focusing on computational biochemistry.

Biography
Phil Johnson is a recognized leader in advancing healthcare innovation through real-world data and digital health solutions. At Evidation, he leverages a community of over 5 million individuals and innovative direct-to-patient, longitudinal data capture capabilities to advance patient-centric health research and accelerate drug development.With deep expertise in technology and real-world data, Phil has a proven track record of improving research and patient outcomes. His previous work includes building Real-World Data initiatives and promoting Clinical Diversity at Tempus AI, as well as launching a healthcare and life sciences division at Amazon Web Services, where he forged strategic partnerships with leading U.S. healthcare organizations.

Talk
Real-world data collected directly from individuals, through surveys, ePROs, and wearables, combined with conventional sources, demonstrates promising potential for generating predictive insights in areas like influenza detection. This approach opens the door to addressing broader challenges, including obesity and related conditions, by empowering individuals and driving advancements in personalized precision medicine.

Biography
Michelle Chen is the Chief Business Officer at Insilico Medicine, a leader in the AI-powered drug discovery and development field. She is responsible for the companys global strategies, business and corporate development, and the US operations. As a biotech executive, Michelle brings in 20+ years of global experience in biopharma and tech-bio industries, having worked at multi-national companies such as Roche, Merck, BioMarin, Agilent, as well as small biotech companies. She has a strong track record of success in company building, BDL, MA, RD, marketing, and product commercialization. Michelle obtained her Ph.D. in Biochemistry from the University of Washington, did her postdoctoral work at UCSF, and received Bioinformatics training at Stanford.