Speaker Profile
PMWC PIONEER AWARD
Contributions to precision medicine using EHRs and data science to enable personalized treatments
M.D., Ph.D., Professor and Chair, Dept of Biomedical Informatics; Editor-in-Chief, NEJM AI, Harvard
Biography
Isaac Kohane is the inaugural chair of Harvard Medical Schools Department of Biomedical Informatics, whose mission is to develop the methods, tools and infrastructure required for a new generation of scientists and care providers to move biomedicine rapidly forward by taking advantage of the insight and precision offered by big data. Kohane develops computational techniques to address disease at multiple scales, from whole health care systems to the functional genomics of neurodevelopment. He has worked on AI applications in medicine since the 1990s, including automated ventilator control, pediatric growth monitoring, detection of domestic abuse, diagnosing autism and assisting clinicians using whole genome sequence and clinical histories to diagnose rare disease patients. He is the inaugural Editor-in-Chief of NEJM AI and co-author of a recent book The AI Revolution in Medicine." He is a member of the National Academy of Medicine, the American Society for Clinical Investigation and the American College of Medical Informatics.
Talk
Session Abstract – PMWC 2025 Silicon Valley
Track Chair:
- William Oh, Mount Sinai
Patient-centric data, such as Real-World Evidence (RWE) and Real-World Data (RWD), has become critical in reshaping drug development and healthcare decision-making. Over the last few years, regulatory agencies like the FDA and EMA have increasingly embraced RWE/RWD for decision-making processes, influencing everything from new drug indications to post-marketing surveillance. The integration of RWE and RWD is not only supporting clinical trial design and regulatory approvals, but also enabling precision medicine by providing deeper insights into patient subpopulations and their outcomes
Sessions:
- PMWC 2025 Award Ceremony
Pioneer Honoree: Isaac Kohane, Harvard
- Keynote: Can AI succeed where humans have failed to personalize medicine?
- Isaac Kohane, Harvard
- From Data to Decisions: Real-Time Patient Insights for Improved Care (PANEL)
Chair: Michael Pfeffer, Stanford Medicine
- Chris Longhurst, UC San Diego Health
- Tanya Townsend, Stanford Children’s
- Kiran Mysore, Sutter Health
- Cherodeep Goswami, UW Health - AI-Powered RWE: Driving Trustworthy Insights and Innovation through Interoperability (PANEL)
Chair: Charles Jaffe, HL7 International
- Data Privacy and Security (and Health Equity) Challenges to the Use of Health Data in AI (PANEL)
Chair: Deven McGraw, Invitae
- Bakul Patel, Google - Accelerating Drug Development with Real World Evidence and AI: Amgen's Journey
- David M. Reese, Amgen
