Session Abstract – PMWC 2024 Silicon Valley

Showcase Track S2 - January 24 2.00 P.M.-2.45 P.M.,Showcase Track S2 - January 25 9.15 A.M.-3.00 P.M.,Showcase Track S2 - January 26 11.00 A.M.-3.45 P.M.


The PMWC 2024 Clinical & Research Tools Showcase will provide a 15-minute time slot for selected companies in this space. The Clinical & Research Tools is a showcase for innovative technologies that are used for the analysis of genetic variation and function, helping to advance breakthroughs in genetic health, rare disease conditions on individuals of all ages, complex diseases and cancer care. Next-generation sequencing (NGS) and microarray technologies empower rapidly evolving genomic revolution.


Confirmed Presenting Companies:

 Speaker Profile

PhD, Founder & CEO, SPOC Proteomics

Biography
Bharath is inventor of multiple foundational life science technologies at the interface of nanotechnology, systems biology and ML/AI, to extract 100x more information from systems biology than currently possible. He conceived Sensor-integrated Proteome On Chip (SPOC) technology to bridge a big gap in proteomics space, to democratize high-throughput functional protein screening. SPOC is the first and only technology that enables production of 1000s of full-length folded proteins on 1.5 sq-cm biosensor chips, to simultaneously screen for qualitative, quantitative, and kinetic information on protein bindings/interactions in a single assay, at once. Bharath is also the inventor of FENT solid-state nanopore technology for 1000x faster DNA sequencing at 1/10th cost, being developed by iNanoBio Inc. He raised $18M private capital and secured about $8M from DARPA, NIH. Bharath’s vision is to achieve 90% disease preemption, which is to detect and intervene in pre-disease phases, to cure before full disease onset.


Talk
SPOC: A Novel, Scalable, Kinetic Proteomics Biosensor
Sensorintegrated proteome on chip (SPOC) is the only proteomics platform capable of delivering quantitative, qualitative, and kinetic (affinity) information in a single assay atscale. At 10100x reduced costs from traditional workflows, SPOC is democratizing highthroughput kinetic proteomics for biomarker discovery, drug discovery, and diagnostics.


Clinical & Research Tools Showcase:
SPOC Proteomics

SPOC Proteomics offers the world’s first proteome-on-biosensor chip capability to support drug and vaccine development, protein biomarker discovery, and diagnostics. SPOC is only platform that provides simultaneous quantitative, qualitative and kinetic data for thousands of full-length folded proteins at once.

 Speaker Profile

ImmunoPrecise Antibodies IPA

Biography
TBA


Clinical & Research Tools:
ImmunoPrecise Antibodies (IPA)

ImmunoPrecise is a biotherapeutic research hub leveraging systems biology, multiomics modelling and complex artificial intelligence systems to support its proprietary antibody discovery technologies. Combining an AI-driven approach with bestinclass laboratory capabilities creates a powerful synergy that is revolutionizing antibody discovery.

 Speaker Profile

CMO, Pillar Biosciences

Biography
Mr. Brian Wright is the Chief Marketing Officer of Pillar Biosciences. He has more than 15 years of experience in the Precision Medicine industry, notably in-vitro diagnostics, molecular diagnostics, liquid biopsy and solid tumor oncology. Prior to joining Pillar Biosciences, Mr. Wright has worked in various leadership roles for Invitae, ArcherDx Diagnostics, Paradigm Diagnostics and Caris Life Sciences. His positions have included oversight of product marketing, corporate development, sales leadership, and commercial development. Mr. Wright received his MBA from Arizona State University and his BA in Biology from Rutgers University


Talk
Enabling Localized Liquid Biopsy Tumor Profiling


Clinical & Research Tools Showcase:
Pillar Biosciences

Pillar Biosciences is the leader in Decision Medicine™, which is the utilization of highly accurate and sensitive next-generation sequencing (NGS) testing technology to quickly and accurately generate data that optimizes selection of precision therapies for cancer patients.

 Speaker Profile

CEO, Biography Health

Biography
Bill Turpin is a seasoned tech entrepreneur who created startups that were pioneers in significant market evolutions, such as Personal Computing, Windows, and the Internet. Throughout his career in Austin and Silicon Valley he’s also served in leadership roles at public companies, such as Netscape, Borland, and Texas Instruments. He has been an advisor to leading venture funds, such as Kleiner Perkins, provides mentoring to fellow innovators, and is an active angel investor. He was included in Ben Horowitz’s book The Hard Thing about Hard Things.


Talk
Accelerating Adoption of Precision Medicine
Widespread clinical adoption of Precision Medicine has been disappointingly slow. This showcase demonstrates how Biography Health is providing clinical decision support so physicians can employ Precision Medicine in their routine practice. We also describe how our cloud based platform can help gather patient data and track clinical outcomes to support large scale clinical trials.


Clinical & Research Tools Showcase:
Biography Health

Biography Health is creating a cloud-based platform to deliver personalized, precision medicine to everyone.

 Speaker Profile

PhD, Sr. Vice President Informatics & Data Officer, Florida Cancer Spec.

Biography
As Senior Vice President Data Officer, Trevor is responsible for ensuring that patients and practice maximize the benefit of data by driving FCS digital innovation strategies. He spearheads initiatives to establish improved utilization of data to enhance precision medicine, clinical decision support, value based care and quality improvement, as well as data initiatives for research, real world evidence and clinical trials. Trevor joined FCS in 2020. During his over 30 years of experience, he has held progressively responsible leadership roles in healthcare, life sciences, software and informatics. Trevor completed his Bachelor of Science with honors in Chemistry and Computer Science at the University of Reading in Reading, UK, where he also earned his doctorate in Organic Chemistry. His work has been published in over 30 peer reviewed scientific journals and books.


Talk
FCS PRECISE: Precision Oncology Clinical Decision Support and Research Solution
Presentation will discuss the challenges of implementing a precision oncology program at a large community oncology practice. FCS PRECISE, our inhouse precision oncology platform, will be discussed including NGS data standardization, clinical decisionsupport, data profiling and visualization, virtual molecular tumor board capabilities, and clinical trial matching.


Clinical & Research Tools Showcase:
Florida Cancer Spec.

Founded in 1984, Florida Cancer Specialists & Research Institute has built a national reputation for excellence that is reflected in exceptional and compassionate patient care, driven by innovative clinical research, cutting-edge technologies and advanced treatments, including targeted therapies genomic-based treatment and immunotherapy.

 Speaker Profile

PhD, Director of R&D, One BioMed

Biography
Dr. Elian Rakhmanaliev is currently leading RD team at One BioMed, a biotechnological company, developing automated cartridge-based nucleic acid extraction instruments and kits. Elian has over 20 years of international academic and industrial experience and expertise in molecular diagnostics, genetics, and molecular biology. For the past 12 years his main focus was on developing NGS, qPCR and IA-based IVD tests, platforms and POCT devices for molecular diagnostics as well as nucleic acid extraction systems. Elian obtained his PhD in Genetics from Vavilov Institute of General Genetics and completed postdoctoral fellowships in Oncology at Karolinska Institute and in Immunogenetics at Johns Hopkins University.


Talk
Accelerating and Simplifying Nucleic Acid Extraction
Introducing an automated microfluidic all-in-one nucleic acid extraction system developed based on a novel reversable chemical binding reaction. The integrated platform and cartridges enable gentle and rapid isolation of nucleic acid (including ultra-HMW DNA) from various sample types or a wide range of research as well as clinical applications.


Clinical & Research Tools Showcase:
One BioMed

One BioMed is a molecular life science company at the forefront of innovation, accelerating the pace of biomedical research through implementation of cutting-edge technologies in developing of instruments and reagents for nucleic acid extraction and testing.

 Speaker Profile

PhD, CEO, Access Sensor Tech

Biography
Dr. Reilly is currently the CEO/CSO at Access Sensor Technologies. The company has licensed and further developed technologies to make sampling our world simple. The company launched its first product, the Ultrasonic Personal Aerosol Sampler, in 2017 which has been adopted by scientists around the world as a key tool for personal environmental pollution exposure measurement. Dr. Reilly has overseen the expansion of the company’s product offerings to serve numerous additional personal health studies. The company is positioned to serve the precision medicine field as it moves to include more environmental measurements and data in the service of better health outcomes for populations and the individual. Thomas is a broadly experienced scientist and entrepreneur with a background in instrumentation commercialization, materials science, next generation renewable energy materials, electronics, photonics, nanomaterials, and analytical chemistry.


Talk
Atoms and Bits to Measure the Exposome
Recent results generated with partners and customers demonstrating improved approaches to measuring the personal exposome will be presented. New tools now make it possible to capture the exogenous factors influencing health with accuracy, precision and ease. These tools lower the barriers to characterizing exposures.


Clinical & Research Tools Showcase:
Access Sensor Tech

Hardware and instrumentation at the intersection of the environment and health. Sampling Made Simple.

 Speaker Profile

PhD, Vice President, Clinical Genomics Operations & Chief of Staff, Cache DNA

Biography
Dr. Williams is a European Board of Medical Genetics Board Certified Clinical Laboratory Geneticist (ErCLG), a UK Health and Care Professions Council (HCPC) registered Clinical Scientist (Genomics) with categorical certifications (Cytogenetics, Molecular Biology) from the American Society of Clinical Pathology (ASCP). Dr. Williams was previously the Head, Cancer Testing at Harbinger Oncology, Director, Clinical Science Oncology at Tempus, and Principal Clinical ScientistDeputy Head with Viapath at the King's College Hospital (London) Haematological Malignancy Diagnostic Centre. She completed an Accreditation Council for Graduate Medical Education (ACGME) ABMGG fellowship at the NewYork Presbyterian Columbia University Irving Medical Center and an Executive Master of Business Administration (Healthcare) at Yale School of Management. Dr. Williams's expertise includes transitioning laboratories to the ISO15189 medical laboratories standard to demonstrate the quality and reliability of their service, advocacy and government affairs for health equity, mentoring women in science biotechnology, and standardization of genomics informed clinical care.


Talk
Navigating the Liquid Biopsy Testing Boom: Sample Management Challenges
The recent explosion in minimally invasive medicine offers promising avenues for early disease detection via MultiCancer Early Detection (MCED) screening assays and monitoring via measurable residual disease (MRD) tests. However, this exciting progress in leveraging genomic data in diagnostics comes with a unique set of challenges in sample management.


Clinical & Research Tools Showcase:
Cache DNA

Cache is helping labs store precious molecular biospecimens (e.g. nucleic acids) with more scalable, sustainable, and standardized approaches. By improving molecular preservation with Cache, labs stand to benefit from cost savings, flexibility, and a broader archive of samples across time.

 Speaker Profile

Ph.D., Director, Computerome

Biography
Peter Longreen, CEO of Computerome. 20 years of experience with HPC in healthcare and research.


Talk
National Infrastructure for AI in the Danish Health System
This showcase introduces Computerome's platform for AI and healthcare. Compliant, flexible, and secure, Computerome is designed to store and process sensitive data. Learn more about Computerome's groundbreaking projects, such as UNITE which leverages registry data and real-time data to improve colorectal cancer care. Computerome provides the building blocks for the future development AI in healthcare.


Clinical & Research Tools Showcase:
Computerome

Computerome is Denmark's national platform for life science and sensitive data research.

 Speaker Profile

Head of Commercial, Sano

Biography
Passionate about finding innovative ways to improve healthcare systems, I lead the commercial team at Sano Genetics, a platform that helps precision medicine clinical operations teams accelerate trials by combining patient finding, genetic testing, and long term engagement.


Talk
Bridging Recruitment, Biomarkers & Engagement
Theo will explore the rising field of precision medicine research and emphasize successes of biomarkerdriven drug development and discuss common challenges, such as patient recruitment, biomarker testing, and patient engagement. A thoughtful framework to streamline recruitment, accelerate enrollment, and reduce costs will be presented, with realworld case studies to demonstrate the effectiveness of this approach.


Clinical & Research Tools Showcase:
Sano

Sano combines genetic testing, recruitment, and long-term engagement in one platform, accelerating enrollment and simplifying operations for precision medicine teams driving breakthroughs for patients.

 Speaker Profile

PhD, CTO, Nimble Science Ltd.

Biography
Passionate and driven to share his technology with this emerging new field, co-founder and inventor Joseph Wang is leading Nimble Science to partner with leading industry partners from around the world. Dr. Wang has deep expertise in wearables and ingestibles with a track record of commercial success. He completed his Ph.D. in Biomedical Engineering at the University of Calgary and his Bachelor in Bioengineering at the National University of Singapore.


Talk
SIMBA Capsule: Powering Novel GI Microbiome Innovation
Nimble Science presents the SIMBA Capsule for clinical sampling of previously inaccessible regions of the GI tract. We will describe how we are working with global industry leaders around the world to deliver novel GI data with transformative impact on healthcare, and the potential for this scalable approach to revolutionize diagnostic and therapeutic precision medicine.


Clinical & Research Tools Showcase:
Nimble Science Ltd.

Nimble Science is a health tech company with a mission is to be the leading global collaborator in delivering actionable intelligence from the GI tract to improve health outcomes.

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