Bharath Takulapalli

Biography
Bharath is inventor of multiple foundational life science technologies at the interface of nanotechnology, systems biology and ML/AI, to extract 100x more information from systems biology than currently possible. He conceived Sensor-integrated Proteome On Chip (SPOC) technology to bridge a big gap in proteomics space, to democratize high-throughput functional protein screening. SPOC is the first and only technology that enables production of 1000s of full-length folded proteins on 1.5 sq-cm biosensor chips, to simultaneously screen for qualitative, quantitative, and kinetic information on protein bindings/interactions in a single assay, at once. Bharath is also the inventor of FENT solid-state nanopore technology for 1000x faster DNA sequencing at 1/10th cost, being developed by iNanoBio Inc. He raised $18M private capital and secured about $8M from DARPA, NIH. Bharath’s vision is to achieve 90% disease preemption, which is to detect and intervene in pre-disease phases, to cure before full disease onset.

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Talk
SPOC: A Novel, Scalable, Kinetic Proteomics Biosensor
Sensorintegrated proteome on chip (SPOC) is the only proteomics platform capable of delivering quantitative, qualitative, and kinetic (affinity) information in a single assay atscale. At 10100x reduced costs from traditional workflows, SPOC is democratizing highthroughput kinetic proteomics for biomarker discovery, drug discovery, and diagnostics.

Clinical & Research Tools Showcase:
SPOC Proteomics
SPOC Proteomics offers the world’s first proteome-on-biosensor chip capability to support drug and vaccine development, protein biomarker discovery, and diagnostics. SPOC is only platform that provides simultaneous quantitative, qualitative and kinetic data for thousands of full-length folded proteins at once.