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 Speaker Profile

M.D., Ph.D., Associate Professor, Stanford

Biography
The focus of my lab is to understand how tissue structure regulates immune tolerance in health and disease. To achieve this, we have leveraged techniques from physics, biochemistry, medicine, and pathology to develop a new framework for spatial biology that has led to the discovery of previously unknown rule sets governing the spatial organization and cellular composition of immune and stromal cells in cancer, infectious disease, and the maternal-fetal interface. In parallel, we have developed open-source algorithms that use machine learning and convolutional neural networks for low-level imaging processing, single-cell segmentation, and categorical classification of larger multicellular features automatically with human-level accuracy. This synergy between spatial proteomics, automated image analysis, and statistical modeling has permitted us to perform large, endpoint-driven studies of archival human tissue and discover previously unknown spatial programs in preinvasive, invasive, and metastatic cancers.


 Session Abstract – PMWC 2026 Silicon Valley

Track 3: Precision Dx - March 6 9.00 A.M.-4.15 P.M.


Track Chair:
Christina Curtis, Stanford

PMWC Award Ceremony
• W.E. Moerner, Stanford
• Serge Saxonov, 10x Genomics
• Priscilla Chan, CZI

Honoree Fireside
• Chair: Christina Curtis, Stanford
• W.E. Moerner, Stanford
• Priscilla Chan, CZI
• Serge Saxonov, 10x Genomics

Unraveling Tissue Architecture with Single-Cell & Spatial Multi-Omics
• Joakim Lundeberg, SciLifeLab
• Garry P. Nolan, Stanford
• Tae Hyun Hwang, Vanderbilt University Medical Center
• Michael Angelo, Stanford

Spatial Sequencing for Next Generation Pathology
• Jeremy Schurman, Singular Genomics

Precision Profiling of Cells: Insights from Imaging-Spectral Flow Cytometry and Single-Cell Multiomics
• Aruna Ayer, BD

Single-Cell Genotype and Targeted Gene Expression Assay
• Zivjena Vucetic, Mission Bio

Tumor Evolution & Clonal Dynamics: From Models to Monitoring
• Chair: Christina Curtis, Stanford

Personal Omics at Scale: What Longitudinal Profiles Add to Early Detection
• Michael Snyder, Stanford

Multi-Omics-Driven Early Detection: Beyond Liquid Biopsy
• Ash Alizadeh, Stanford
• Alex Aravanis, Moonwalk Biosciences
• Sara Ahadi, OmicsEra

AI in Molecular Diagnostics: Integrating Multi-Omics & Clinical Data
• Chair: Marina Sirota, UCSF
• Olivier Gevaert, Stanford
• Rebecca Critchley-Thorne, Castle Biosciences
• Lihua Lei, Stanford
• Yunguan Wang, Cincinnati Children's

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