Speaker Profile
M.D., Ph.D., Professor, Stanford
Biography
Michael Angelo is a board-certified pathologist and assistant professor in the department of Pathology at Stanford University School of Medicine. Dr. Angelo is a leader in high dimensional imaging with expertise in tissue homeostasis, tumor immunology, and infectious disease. His lab has pioneered the construction and development of Multiplexed Ion Beam Imaging by time of flight (MIBI-TOF). MIBI-TOF uses secondary ion mass spectrometry and metal-tagged antibodies to achieve rapid, simultaneous imaging of dozens of proteins at subcellular resolution. In recognition of this achievement, Dr. Angelo received the NIH Directors Early Independence award in 2014. His lab has since used this novel technology to discover previously unknown rule sets governing the spatial organization and cellular composition of immune, stromal, and tumor cells within the tumor microenvironment in triple negative breast cancer. These findings were found to be predictive of single cell expression of several immunotherapy drug targets and of 10-year overall survival. This effort has led to ongoing work aimed at elucidating structural mechanisms in the TME that promote recruitment of cancer associated fibroblasts, tumor associated macrophages, and extracellular matrix remodeling. Dr. Angelo is the recipient of the 2020 DOD Era of Hope Award and a principal investigator on multiple extramural awards from the National Cancer Institute, Breast Cancer Research Foundation, Parker Institute for Cancer Immunotherapy, the Bill and Melinda Gates Foundation, and the Human Biomolecular Atlas (HuBMAP) initiative.
Session Abstract – PMWC 2026 Silicon Valley
Track Chair:
Christina Curtis, Stanford
PMWC Award Ceremony
• W.E. Moerner, Stanford
• Serge Saxonov, 10x Genomics
• Priscilla Chan, CZI
Honoree Fireside
• Chair: Christina Curtis, Stanford
• W.E. Moerner, Stanford
• Priscilla Chan, CZI
• Serge Saxonov, 10x Genomics
Unraveling Tissue Architecture with Single-Cell & Spatial Multi-Omics
• Joakim Lundeberg, SciLifeLab
• Garry P. Nolan, Stanford
• Tae Hyun Hwang, Vanderbilt University Medical Center
• Michael Angelo, Stanford
Spatial Sequencing for Next Generation Pathology
• Jeremy Schurman, Singular Genomics
Precision Profiling of Cells: Insights from Imaging-Spectral Flow Cytometry and Single-Cell Multiomics
• Aruna Ayer, BD
Single-Cell Genotype and Targeted Gene Expression Assay
• Zivjena Vucetic, Mission Bio
Tumor Evolution & Clonal Dynamics: From Models to Monitoring
• Chair: Christina Curtis, Stanford
Personal Omics at Scale: What Longitudinal Profiles Add to Early Detection
• Michael Snyder, Stanford
Multi-Omics-Driven Early Detection: Beyond Liquid Biopsy
• Ash Alizadeh, Stanford
• Alex Aravanis, Moonwalk Biosciences
• Sara Ahadi, OmicsEra
AI in Molecular Diagnostics: Integrating Multi-Omics & Clinical Data
• Chair: Marina Sirota, UCSF
• Olivier Gevaert, Stanford
• Rebecca Critchley-Thorne, Castle Biosciences
• Lihua Lei, Stanford
• Yunguan Wang, Cincinnati Children's
