Speaker Profile
Ph.D., CEO and Co-Founder, Pi.Bio & ShapeTX
Biography
François Vigneault is a serial biotechnologist, co-founder of Pi.Bio, ShapeTX, and AbVitro. Pi.Bio develops next-generation human-derived small proteomic-ligand therapies for immuno-inflammatory diseases, oncology, and gene delivery. ShapeTX is an AI-driven RNA editing gene therapy company leveraging ADAR technology. AbVitro, acquired by Juno Therapeutics (later Celgene and Bristol Myers Squibb), pioneered high-throughput immune single-cell sequencing for antibody and TCR discovery. François completed his postdoctoral work with George Church at Harvard Medical School and served as a Maritime Warfare Officer in the Canadian Navy.
Session Abstract – PMWC 2025 Silicon Valley
Track Co-Chairs:
Yael Weiss, Mahzi Tx
Morten Sogaard, Astellas Gene Therapies
- PMWC 2025 Award Ceremony
Pioneer Honoree: James M. Wilson, Gemma Biotherapeutics
Luminary Honoree: Carolyn Bertozzi, Stanford
- Keynote: Bioorthogonal Chemistry, from Basic Science to Clinical Translation
- Carolyn Bertozzi, Stanford
- Keynote: The Promise of Genetic Medicines Unless You're Too Poor or Too Rare
- James M. Wilson, Gemma Biotherapeutics
- Barriers in Gene Therapy
Chair: Timothy Hunt, Alliance for Regenerative Medicine
- Tay Salimullah, 4BIO Capital
- James M. Wilson, Gemma Biotherapeutics
- Courtney Silverthorn, Bespoke Gene Therapy Consortium (BGTC) - Next-Generation Delivery Systems for Gene Therapies (PANEL)
Chair: James M. Wilson, Gemma Biotherapeutics
- Mathieu Nonnenmacher, Voyager Therapeutics
- Kevin Friedman, Kelonia Therapeutics
- Kunwoo Lee, GenEdit
- Haig Aghajanian, Capstan Therapeutics
- Beyond the Genome: Harnessing Epigenetics in Rare Disease Treatment (PANEL)
Chair: Charles Gersbach, Duke
- Prashant Mali, UCSD
- Nadav Ahituv, UCSF
- Blythe Sather, Tune Therapeutics
- Fyodor D Urnov, Berkely University
- Navigating the Regulatory Landscape for Gene and Cell Therapies (PANEL)
Chair: Yael Weiss, Mahzi Tx
- Rob Califf, FDA
- Courtney Silverthorn, Bespoke Gene Therapy Consortium (BGTC)
- Ben Dewees, Kyverna Therapeutics
- Paul Kruszka, GeneDx
- AI-driven Improvements in Gene and Cell Therapy (PANEL)
Chair: John Androsavich, Ginkgo Bioworks
- Francois Vigneault, Shape Therapeutics
- Eeshit Dhaval Vaishnav, Sequome
- Sam Sinai, Dyno Therapeutics
- Kira Radinsky, mana.bio
