Speaker Profile
MD, PhD, President, Research and Development, Kyverna Tx
Biography
Dominic Borie is an accomplished immunologist and transplant surgeon with extensive experience in drug development. Before joining Kyverna, he held leadership positions at Horizon Therapeutics, Genentech, Amgen, and Roche. Dr. Borie has an extensive publication history with over 50 publications in peer reviewed journals, 10 book chapters, and four issued patents. He received his Ph.D. in transplantation immunology from the University of Paris V Descartes and his M.D., Masters degree in Immunology, and Certificate of Immunology and Immunopathology from the University of Paris XII.
Talk
Transformative Outcomes With CAR-T Cell Therapy for Autoimmune Diseases
Kyverna Therapeutics is working to transform outcomes for patients with autoimmune diseases with KYV101, a fully human antiCD19 CAR-T cell therapy with structural features that confer a safety profile well suited for use in autoimmune diseases. Kyverna has treated patients with multiple autoimmune diseases in sites around the world.
Session Abstract – PMWC 2024 Silicon Valley
Track Co-Chairs:
Yael Weiss, Mahzi Tx
Peter Marks, FDA
- PMWC 2024 Award Ceremony
Pioneer Honoree: Katherine A. High, AskBio
Pioneer Honoree: Timothy Yu, Boston Children's Hospital
- Piloting Interventional Genomics for Orphan Diseases
Keynote: Timothy Yu, Boston Children's Hospital
- Accelerated Approval for Small Populations: Biomarkers & Endpoints (PANEL)
Chair: Peter Marks, FDA
- Jennifer Puck, UCSF
- Maria Grazia Roncarolo, Tr1X
- Katherine A. High, Rockefeller University
- Jennifer Panagoulias, FAST (Angelman Syndrome Foundation)
- Timothy Yu, Boston Children's Hospital - Novel Clinical Design Approaches in Rare Diseases (PANEL)
Chair: Adam Shaywitz, Bridge Bio
- Salvador Rico, Encoded Therapeutics
- Eric Crombez, Ultragenyx
- Elizabeth Berri Kravis, Rush University
- Empowering Patient Advocacy in Rare Disease Therapies (PANEL)
Chair: Yael Weiss, Mahzi Tx
- Justin West, KCNT1 Foundation
- Michael Graglia, Syngap Research Fund
- Wendy Erler, Alexion Pharmaceuticals - Advancing the Frontier: Gene Editing for Rare Diseases (PANEL)
Chair: Matthew Porteus, Stanford
- James Chung, Kyverna Therapeutics
- Lucas Harrington, Mammoth Biosciences
- Aron Stein, Intellia Therapeutics - Advancing the Frontier: Gene and Cell Therapies for Rare Diseases (PANEL)
Chair: Morten Sogaard, Astellas Gene Therapies
- Pooja Agarwal, BioMarin Pharmaceutical
- David Kirn, 4dmt
- Adrian Veres, Dyno Therapeutics
- Thomas Wechsler, J&J
- PMWC Showcase
- Dominic Borie, Kyverna Therapeutics
