Speaker Profile
Biography
Dr. Ledbetter is an internationally recognized expert in Genomics and Precision Medicine, focusing his early research efforts on discovering the genetic causes of childhood neurodevelopmental disorders, and the translation of new genomics technologies into clinically useful genetic tests for early diagnosis and intervention. He served as EVP and Founding Chief Scientific Officer at Geisinger for ten years (2010-2021), leading their ground-breaking genomics program-the first in the world to return medically actionable results to patient-participants.He held academic and leadership positions at Emory University, the University of Chicago, and Baylor College of Medicine, and is currently Professor at the Florida State University, where he is leading a new statewide pediatric genetics network funded by the State of Florida through the Sunshine Genetics Act to move whole genome sequencing into universal newborn screening for hundreds of rare diseases. He is a graduate of Tulane University and earned his Ph.D. at the University of Texas-Austin.
Session Abstract – PMWC 2026 Silicon Valley
Track Chair:
Burns Blaxall
PMWC Award Ceremony
• Euan Ashley, Stanford
• Jeffrey R. Balser, Vanderbilt
• Howard J. Jacob, Abbvie
Precision Medicine at Scale: Lessons from Vanderbilt
• Jeffrey R. Balser, Vanderbilt
From First Patient to a Million Genomes
• Chair: Howard J. Jacob, Abbvie
• Jeffrey R. Balser, Vanderbilt
• Euan Ashley, Stanford
Keynote: AI and Data-Driven Individual Health: Optimizing Wellness, Preventing Disease and Empowering Precision Medicine
• Lee Hood, Phenome Health
Keys to successful implementation of a Precision Medicine Program
• Chair: Howard McLeod, GeneDx
• Kevan Simms, Ochsner Health
• Chris Lunt, NIH
Key players in successful implementation – Beyond Oncology
• Chair: Damon Hostin, Illumina
• Shaista Malik, UC Irvine
• David E. Lanfear, Henry Ford Health
• Oren Caspi, Rambam
Precision Medicine at Scale: Lessons from a Statewide Genomic Initiative
• Chair: Premal Shah, MyOme
• Niall Lennon, Broad Clinical Labs
Integrating Multi-Modal Biology into Precision Care Pathways: A Systems Framework for Scalable Implementation
• K V Venkatesh, IIT Mumbai
Fireside Chat: From $/Gb to Outcomes: Simplifying Genomics for Health Systems
• Jacob Thaysen, Illumina
Achieving Comprehensive Precision Medicine
• Chair: Burns Blaxall
• Trish Brown, GeneDx
• Charles Sailey, Molecular Testing Labs
• Sarah Hersey, BMS




