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M.D., Ph.D., Profesor, UCSF

Biography
Chaz Langelier, M.D., Ph.D., is a Professor of Medicine at the University of California, San Francisco and an infectious disease physician-scientist whose work applies genomics and multi-omics to difficult diagnostic problems. His laboratory develops approaches that measure pathogens, host immune responses, and the microbiome directly from clinical samples, with the goal of improving diagnosis and treatment of pneumonia, sepsis, and other infectious or inflammatory syndromes. Dr. Langelier combines metagenomic sequencing, transcriptomics, machine learning, and clinical investigation to distinguish infection from noninfectious disease and to identify biological signals associated with severity and outcomes. He joined the UCSF faculty in 2017 and has also served as a Chan Zuckerberg Biohub Investigator. His work is particularly relevant when conventional microbiology is slow or inconclusive, or when immunocompromised patients have complex presentations. By integrating microbial and host data, Dr. Langelier aims to create more informative diagnostics and a more precise basis for antimicrobial and immunomodulatory treatment decisions.


 Session Abstract – PMWC 2027 Silicon Valley

Track 3: Precision Dx - Jan 28 2.15 P.M.-2.30 P.M.,Track 3: Precision Dx - Jan 29 9.00 A.M.-4.30 P.M.


Track Chair:
Christina Curtis, Stanford

PMWC Award Ceremony
• Joe DeRisi, UCSF / CZ Biohub / Delve Bio (Luminary)
• Alexandre Loupy, Inserm / Paris Transplant Group (Pioneer)

Featured Speakers
• Joe DeRisi, UCSF / CZ Biohub / Delve Bio
• Alexandre Loupy, Inserm / Paris Transplant Group
• Minnie Sarwal, UCSF
• Kiran Khush, Stanford
• Iwijn De Vlaminck, Cornell
• Maarten Naesens, KU Leuven
• Charles Chiu, UCSF
• Michael Snyder, Stanford
• Duncan MacCannell, CDC
• Chaz Langelier, UCSF
• Yoel Sadovsky, Stanford
• Ananth Karumanchi, Cedars-Sinai
• Gabriel Bien-Willner, Palmetto GBA / MolDX
• Dawn Cardeiro, Roche Diagnostics
• Bruce Quinn, Bruce Quinn Associates

Transplant & Organ Health Diagnostics
From biopsy to blood-based monitoring of rejection, injury, and infection.

Blood-Based Omics and Host Response in Infection
Metagenomics and host-response signals for difficult infectious disease cases.

Maternal & Fetal Health
From prenatal screening to actionable maternal and placental biomarkers.

From Signal to Standard of Care
What makes a non-cancer blood test clinically actionable and reimbursable.

Davos of Precision Medicine

PMWC 2027 Program

January 27–29, 2027 · Santa Clara Convention Center

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