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 Session Abstract – PMWC 2026 Silicon Valley

Track 2: AI - March 4 1.30 P.M.-1.45 P.M.,Track 2: AI - March 6 9.00 A.M.-4.15 P.M.


Track Chair:
Alex Morgan, Khosla Ventures and Gad Getz, Broad Institute

PMWC Award Ceremony
• Steve Wozniak, Apple
• Greg Brockman, OpenAI

Fireside Chat
• Vinod Khosla, Khosla Ventures
• Greg Brockman, OpenAI

Target Discovery: Beyond Genomics – Revealing Hidden Layers of Biology with AI
• Keynote: Stephen Quake, CZ Biohub
• Chair: Cindy Lawley, Olink
• Aritro Nath, City of Hope
• Massa Shoura, Phinomics
• Omar Serang, DNAnexus

Accelerating Immunotherapy Discovery Through Multimodal AI
• Ron Alfa, Noetik

A Data-Integrated Approach to Target and Biomarker Discovery
• Liat Dassa, Cytoreason

Harmonizing Data to Accelerate Drug Discovery
• Vitalay Fomin, Numenos

Closing the Loop: Coupling AI with In Vivo Validation
• Gabriel Musso, Biosymetrics

Interpretable AI for Biomarker Discovery: Accelerating Drug Development
• Sanoj Punnen, University of Miami
• Shivanni Kummar, OHSU
• Mark Burkard, UI

Can AI Really Create the Next Blockbuster Drug?
• Chair: Amar Das, Guardant Health
• Ari Caroline, Weave Bio
• Dina Katabi, Emerald/MIT
• Andrei Georgescu, Vivodyne
• James Zou, Stanford

Gemini Digital Twins Accelerate Precision Medicine
• Collin Hill, Aitia

Scaling Rare Disease Discovery with AI
• Lisa Gurry, GeneDx

Enabling Targeted Precision Drug & Gene Delivery with Predictive AI
• Andre Watson, Ligandal

Is AI the New Drug or the New Therapeutic Modality
• Chair: Alex Morgan, Khosla Ventures
• Michael J. Kahana, Nia Therapeutics
• Marc Tessier-Lavigne, Xaira

 Speaker Profile

Ph.D., Director, Cancer Genome Analysis & Professor of Pathology, MGH & Broad Inst.

Biography
Dr. Getz is an internationally acclaimed leader in cancer genomics and is pioneering widely used tools for analyzing cancer genomes. Dr. Getz is a Professor of Pathology at Harvard Medical School. He is the Director of Bioinformatics at the Massachusetts General Hospital (MGH) Cancer Center and Department of Pathology, and is an Institute Member of the Broad Institute of MIT and Harvard, where he directs the Cancer Genome Computational Analysis Group. He has published over 400 papers inprominentjournals describing new methodologies to study cancer genomesthat haveidentified new genes and pathways involved in different tumortypes,mutational signatures, and tumor evolution.


 Speaker Profile

CSO & COO, Clear Labs

Biography
As Chief Scientific Officer for Clear Labs, Dr. Khaksar leads the vision and strategy for talented teams of dedicated scientists who make life healthier through the application of genomics and intelligent analytics. From a leadership perspective, he prioritize team culture and empower my team members to maximize their talents and push the bounds of what's possible. As a scientist and researcher, Dr. Khaksar have deep insights into the world of health, biotechnology, and next generation sequencing, and Ihe continue to contribute to the world of academia as an adjunct faculty member at Rutgers University. Dr. Khaksar like to leave a legacybyraising the quality of life and health of the world's population.Throughhis work at Clear Labs, they have made a huge impact on foodsafety. Dr.Khaksar aim to expand that impact by using my skills toimprove clinicaland pharmaceutical genomics and their effectiveness inpublic health.


Sequencing Technologies Showcase:
Clear Labs

Clear Labs harnesses the power of next-generation sequencing (NGS) to simplify complex diagnostics for clinical and applied markets. By creating a fully automated platform that brings together DNA sequencing, robotics and cloud-based analytics, Clear Labs democratizes genomics applicationstodeliver increased clarity.

 Speaker Profile

Ph.D., Associate Professor of Biomedical Data Science, Stanford U.

Biography
James an Associate Professor of Biomedical Data Science and, by courtesy, of Computer Science and Electrical Engineering at Stanford University. James works on making AImore reliable, human-compatible and statistically rigorous, and am especially interested in applications in human disease and health. James received his Ph.D from Harvard in 2014, and was at one time a member of Microsoft Research, a Gates Scholar at Cambridge and a Simons fellow at U.C. Berkeley. James joined Stanford in 2016 and am excited to also be a Chan-Zuckerberg Investigator. We are also a part of the Stanford AI Lab. His research is supported by two Chan-Zuckerberg Biohub Investigator Awards, the Sloan Fellowship, the NSF CAREER Award, a Top Ten Clinical Achievement Award and faculty awards from Google, Adobe and Amazon.


 Speaker Profile

Ph.D., Co-Founder & CEO, Nia Tx

Biography
Dr. Michael Kahana is CEO and co-founder of Nia Therapeutics, which is developing an AI-guided closed-loop neurostimulation therapy for memory loss.During his 30-year academic career, Kahana published more than 200 scientific articles and won numerous awards for his pioneering research on the neural basis of human memory and for his contributions ot memory theory.


 Speaker Profile

Co-founder, CSO, Weave Bio

Biography
Ari is Cofounder and CSO at Weave Bio. Weaves native-AI regulatory platform helps life science companies to weave together data and documentation for all regulatory submissions, from pre-IND to NDABLA, directly from the source data and studies.Previously, Ari was the first Chief Analytics Officer at Memorial Sloan Kettering Cancer Center (MSK) where he drove pioneering efforts using clinical data to analyze patient outcomes. Aris team at MSK developed the first operational AI model to match patients to clinical trials. While at MSK, Ari also contributed to the creation of startups like Flatiron Health and Paige AI. In 2019, Ari cofounded Daat.AI which was acquired by Tempus AI, where Ari served as SVP of RWD.


 Speaker Profile

Ph.D., Professor, Co-Founder, MIT, Emerald

Biography
Dina Katabi is the Thuan and Nicole Pham Professor of Electrical Engineering and Computer Science at MIT, and the President and CEO of Emerald Innovations inc. Katabi isa recipient of the MacArthur Fellowship, and a member of the National Academy of Engineering, the National Academy of Sciences, and the American Academy of Arts and Sciences. Her research focuses on innovations indigital health, wireless biosensing, and machine learning.


 Speaker Profile

Ph.D., Assistant Professor, City of Hope

Biography
Dr. Nath is a cancer biologist with expertise in both experimental andcomputational biology. At City of Hope, Dr.Nath leads a collaborative research team that investigates the potential ofAIML in enhancing cancer patient outcomes. Through the integration of bioinformatics andAIML tools, his research aims tounravel the underlying mechanisms of tumor progression and establishcutting-edge biomarkers for improving the clinical outcomes of patientswith cancer. His research employs multi-omics approaches to identify the drivers of tumor evolutionand the subsequent development of drug resistance. Dr. Nath aspires totranslate research findings into clinical impact, notably contributing to upcoming clinical trials in lung and breast cancer that will implement novel AI-guided biomarkers. Dr. Nath currently is aprincipal investigator (PI) of an ARPA-H grant, an NIH U01 grant, a PHASE ONE foundation grant, a JKTG foundation grant, andco-investigator of an ARPA-H and California Institute for Regenerative Medicine (CIRM)grant.


 Speaker Profile

M.D., Founder, Khosla Ventures

Biography
Vinod Khosla is an entrepreneur, investor, and technology fan. He is the founder of KhoslaVentures, focused on impactful technology investments in software, AI, robotics, 3Dprinting, healthcare and more. Mr. Khosla was a co-founder of Daisy systems and foundingCEO of Sun Microsystems where he pioneered open systems and commercial RISCprocessors. One of Mr. Khoslas greatest passions is being a mentor to entrepreneurs,assisting entrepreneurs and helping them build technology-basedbusinesses. Mr. Khosla isdriven by the desire to make a positive impact through technology to reinvent societalinfrastructure and multiply resources. He is also passionate about Social Entrepreneurship.Vinod holds a Bachelor of Technology in Electrical Engineering from IIT, New Delhi, aMaster's in Biomedical Engineering from Carnegie Mellon University and an MBA from theStanford Graduate School of Business.


 Speaker Profile

M.D.,Ph.D., Partner, Khosla Ventures

Biography
Alex's focus at Khosla Ventures is in biotechnology, healthcare, data science, and AIML.


 Speaker Profile

PMWC LUMINARY AWARD
Transforming science and medicine with Generative AI

President and Co-Founder, OpenAI

Biography
Greg Brockman is the President and Co-Founder of OpenAI, where he currently leads the companys Scaling organizationfocused on expanding the technical infrastructure and systems needed to support OpenAIs rapid growth and increasingly capable models. He has played a central role in shaping OpenAIs mission and in bringing transformative technologies like ChatGPT, DALLE, and Codex to millions of people and businesses around the world.Before OpenAI, Greg was the CTO of Stripe, where he built and led the engineering team during a period of rapid scale. He studied mathematics at Harvard and computer science at MIT before leaving to pursue a career at the forefront of technology.Greg is a technologist and builder, deeply invested in ensuring artificial general intelligence is developed safely and benefits all of humanity. He regularly speaks on the future of AI, responsible deployment, and the infrastructure powering the next generation of intelligent tools.


Talk
Fireside Chat


 Speaker Profile

Ph.D., Dual PhD., CEO and CSO, Phinomics

Biography
Massa Shoura is the CEO and CSO of Phinomics, an innovative companytransforming precision medicine by unlocking the potential of circular DNAand integrating genomics with advanced AI. With dual PhDs in MolecularBiology and Biomedical Engineering, Massa has over a decade of expertise inDNA topology, biophysics, and genomics. During her postdoctoral fellowshipat Stanford University in Nobel Laureate Dr. Andrew Fires lab, shedeveloped groundbreaking tools for isolating and characterizing circularDNA, earning prestigious fellowships, including the Arnold O. BeckmanFellowship, and securing two granted patents. As a Forbeck Scholar, sheadvanced cancer genomics by uncovering the role of oncogenic circular DNAamplification. She also spearheaded the sequencing and publication ofPfizer and Moderna COVID-19 vaccine mRNAs, showcasing her commitment toglobal health. At Phinomics, Massa leads the development of first-in-classprecision oncology solutions through the Circulome Atlas, a transformativeplatform providing unparalleled insights into cancer etiology, progression,and therapeutic resistance.


 Speaker Profile

EVP and GM, Regulatory and Government Solutions, DNAnexus

Biography
Omar has decades of experience designing global cloud platforms pioneering the use of collaborative feedback networks to solve challenging information extraction problems. He is the Principal Architect of precisionFDA.gov, the FDA cloud platform that is transforming the regulatory research and review process for precision drugs and devices. Prior to DNAnexus, Omar managed operations for the AWS Elastic Compute Cloud when single regions were topping the one-million server mark. Previously, he led platforms for a Twitter search engine at Topsy Labs, and crowd-sourced messaging security at Cloudmark. Omar received his Bachelor of Science in Chemistry from UC Berkeley.


 Speaker Profile

President, Chairman, & Co-Founder, OpenAI

Biography
Greg Brockman is the President and Co-Founder of OpenAI, where he currently leads the company’s Scaling organization—focused on expanding the technical infrastructure and systems needed to support OpenAI’s rapid growth and increasingly capable models. He has played a central role in shaping OpenAI’s mission and in bringing transformative technologies like ChatGPT, DALL·E, and Codex to millions of people and businesses around the world. Before OpenAI, Greg was the CTO of Stripe, where he built and led the engineering team during a period of rapid scale. He studied mathematics at Harvard and computer science at MIT before leaving to pursue a career at the forefront of technology. Greg is a technologist and builder, deeply invested in ensuring artificial general intelligence is developed safely and benefits all of humanity. He regularly speaks on the future of AI, responsible deployment, and the infrastructure powering the next generation of intelligent tools.


 Speaker Profile

M.D., Founder, Khosla Ventures

Biography
Vinod Khosla is an entrepreneur, investor, and technology fan. He is the founder of KhoslaVentures, focused on impactful technology investments in software, AI, robotics, 3Dprinting, healthcare and more. Mr. Khosla was a co-founder of Daisy systems and foundingCEO of Sun Microsystems where he pioneered open systems and commercial RISCprocessors. One of Mr. Khoslas greatest passions is being a mentor to entrepreneurs,assisting entrepreneurs and helping them build technology-basedbusinesses. Mr. Khosla isdriven by the desire to make a positive impact through technology to reinvent societalinfrastructure and multiply resources. He is also passionate about Social Entrepreneurship.Vinod holds a Bachelor of Technology in Electrical Engineering from IIT, New Delhi, aMaster's in Biomedical Engineering from Carnegie Mellon University and an MBA from theStanford Graduate School of Business.


 Speaker Profile

PMWC PIONEER AWARD
Pioneer of personal computing who engineered the foundation for today’s AI revolution.

Co-Founder, Apple

Biography
A Silicon Valley icon, technology entrepreneur, and philanthropist for more than four decades, Steve Wozniak has helped shape the computing industry through his design of Apples first line of productsthe Apple I and IIand his influence on the Macintosh. In 1976, Wozniak and Steve Jobs co-founded Apple Computer Inc. with Wozniaks Apple I, followed by the Apple II, which helped launch the personal computer revolution. He is listed as the sole inventor on four Apple patents.After completing his degree in electrical engineering and computer science at UC Berkeley, Wozniak founded Unuson, producer of the US Festivalsa landmark fusion of technology and music. His achievements have been recognized with the National Medal of Technology from President Ronald Reagan, induction into the National Inventors Hall of Fame, and the Heinz Award for Technology, the Economy and Employment.A committed advocate for education and innovation, Wozniak has championed technology access in schools and supported institutions such as the Electronic Frontier Foundation, the Tech Museum of Innovation, and the Childrens Discovery Museum of San Jose. He is the author of the New York Times best-selling autobiography iWoz and continues to advance technology education as co-founder of Woz U and Efforce, a blockchain-based sustainability platform.


 Speaker Profile

Ph.D., Co-Founder & CSO, BioSymetrics (Lunai)

Biography
Dr. Musso has a background in molecular genetics (PhD), and didpost-doctoral work at Harvard Medical School and Brigham and Women'sHospital on computational and developmental biology. He spent time at astart-up working on real-time machine learning, before joining with othersto start BioSymetrics with the aim of tackling the specific challenges ofworking with biomedical data. He was named one of the top 100 leaders in AIand drug discovery, has authored over 30 peer reviewed publications on AIMLand biology.


Talk
Closing the loop: Coupling AI with In vivo validation
AI models are accelerating target and compound discovery, but translation remains a bottleneck. We present a closed-loop platform integrating predictive AI with high-throughput in vivo validation using disease models relevant to neurological disease. Case studies demonstrate how this approach improves hit prioritization, enhances biological relevance, and increases success rates in drug development.


 Speaker Profile

Ph.D., CEO, Vivodyne

Biography
Dr. Georgescu spearheads Vivodyne's vision of reshaping therapeutics development. The loss of translation between animal studies and human trials compelled him to co-found Vivodyne in 2020 and create an entirely new platform from the ground up. With a Ph.D. from Dr. Huh's esteemed organ-chip research group at the University of Pennsylvania, his expertise lies in human-tissue engineering, robotics, and machine learning. His prior achievements include sending lab-grown tissues with NASA to space and developing DNA synthesis chips that remain industry staples to this day.


 Speaker Profile

Ph.D., CSO & Co-Founder, Adaptive Biotech

Biography
Harlan Robins is a CoFounder of Adaptive Biotechnologies, a commercialstage biotech company that aims to translate the genetics of the adaptiveimmune system into clinical products to diagnose and treat disease. Priorto cofoundingconfounding Adaptive, Harlan served in various roles at theFred Hutchinson Cancer Research Center (FHCRC) in the Computational BiologyProgram, including Assistant Faculty Member, Associate, and Full Member andHead of the program. Interested in the mathematics behind genetics andobserving the potential utility of high level mathematics to study problemsin the biological sciences, Harlan took a postdoctoral appointment at theInstitute for Advance Study in Princeton under famed biologist Dr. ArnoldLevine. With Dr. Levine, he concentrated on developing bioinformaticalgorithms for micro RNA targets and bacterial genome analysis, a precursorto his faculty appointment at FHCRC in the Computational Biology Group,Public Health Sciences and Human Biology Divisions.


 Speaker Profile

Ph.D., CEO, Numenos

Biography
Vitalay Fomin, Ph.D.,CEO of Numenos AI, is an award-winning data scientist at RocheGenentech specializing in biomarker and reverse translation drug discovery


Talk
CURE AI provides efficacy signal from single arm trials
We developed a novel foundation model that is biologically awarecapable of using single arm trials to identify optimal indication, patient population and drug combination and optimizes each asset for maximal clinical trial success


 Speaker Profile

M.D.,Ph.D., Vice President, Real World Evidence, Guardant Health

Biography
Dr. Amar Das has three decades of experience in advancing clinical researchthrough data science and AI. At Guardant Health, he leads a team thatgenerates real world evidence for blood-based testing in precision oncologyand cancer screening. Prior to Guardant Health, Dr. Das was on the facultyat Stanford and Dartmouth. As Director of Biomedical Informatics atDartmouth, he co-founded the Department of Biomedical Data Science, thefirst department focused on this discipline. Following his career inacademia, he served as Director of Healthcare Effectiveness Research at IBMand Director of Real World Data Analytics and Innovation at MerckMSD. Dr.Das has received multiple professional and research awards, and is a Fellowof the American College of Medical Informatics. Dr. Das received his MD andPhD in Biomedical Informatics from Stanford and completed his residency andpostdoctoral fellowship in Clinical Epidemiology at ColumbiaNew YorkPresbyterian.


 Speaker Profile

Founder & CEO, Ligandal

Biography
Watsons current work focuses on AI-driven biomolecular design, creatingpredictive peptides and receptor-targeting ligands that are engineered toprecisely deliver nanoparticles, gene-editing tools, drugs, and nucleicacids to specific cells and tissues. This approach aims to enhancetherapeutic specificity, reduce toxicity, and accelerate the development ofcurative and preventative delivery of therapeutics. Previously, whileresearching at Rensselaer Polytechnic Institute, he developed gene-editingdelivery platforms for guided nucleases like CRISPR and TALEN. Today, heapplies AI and predictive physics to rapidly generate and evaluate noveltargeting agents, mapping uncharted receptor-ligand relationships as anenabling technology for biopharmaceutical delivery systems. With over 80pending global patents (22 approved, 6 allowed), Watsons work pioneeredintegrating cell surface transcriptomics, predictive targeting liganddesign, and drug and gene delivery systems. He and his team aim totransform how we approach the worlds most challenging diseases, advancingthe frontier of precision therapeutics and diagnostically-responsivemedicine.


 Speaker Profile

CEO + Co Founder, Aitia

Biography
Colin Hill is a trailblazer in applying causal AI to precision medicine. Aitia, the company he co-founded and leads, has built a powerful Digital Twin discovery and drug development platform, with a current focus on neurodegenerative diseases and oncology. He serves on the boards of Fulcrum Therapeutics (NASDAQ: FULC, a rare genetic disease company, Centrexion Therapeutics, a non-opioid pain therapeutics company, and the Critical Path Institute, which fosters collaborations between scientific and regulatory bodies.He previously served on the boards of mobile health company Biotelemetry Inc., CRO PPD Inc., and sickle cell disease company AesRx.In 2004, Colin was named to MIT Technology Reviews TR100 list of the top 100 innovators in the world under the age of 35. He has appeared in publications and television programs including The Wall Street Journal, CNBC Morning CallSquawkBox, Nature, Boston Globe, Politico, Forbes, Wired, and The Economist.


Talk
Gemini Digital Twins Accelerate Precision Medicine
The biggest obstacle to realization of precision medicine is poor knowledge of the complex biological circuitry underlying human health and disease. The convergence of raw computational power, multiomic and clinical data, and causal AI has led to Gemini Digital Twins, in silico circuitry models of virtually any disease (we will discuss Huntington's and prostate cancer).


 Speaker Profile

M.D., Ph.D., CSO, Microsoft

Biography
Eric Horvitz, MD, PhD, is Chief Scientific Officer at Microsoft where he leads initiatives at the intersection of science, technology, and society, with emphases on artificial intelligence, biosciences, and healthcare. His research contributions have advanced AI through innovations in perception, reasoning, and decision-making under uncertainty.Dr. Horvitz is known for his contributions to AI theory and practice, with a focus on principles and applications of AI amidst the complexities of the open world. His direction-setting research efforts include harnessing probability and utility in machine learning and reasoning, developing models of bounded rationality, constructing systems that perceive and act via interpreting multisensory streams of information, and pioneering principles and mechanisms for supporting human-AI collaboration and complementarity. His efforts and collaborations have led to fielded systems in healthcare, transportation, ecommerce, operating systems, and aerospace.Beyond his scientific work, he has pursued programs, organizations, and studies on ethics, values, and safety with applications and influences of AI. He founded and chairs Microsofts Aether committee on AI, effects, and ethics in engineering and research. He established the One Hundred Year Study on AI(opens in new tab) at Stanford University and co-founded and served as board chair of the Partnership on AI(opens in new tab) (PAI). He served as a Congressionally appointed commissioner on the National Security Commission on AI(opens in new tab), where he chaired the line of effort on ethical and trustworthy AI.Dr. Horvitz received the Feigenbaum Prize and the Allen Newell Prize for his fundamental contributions to the science and practice of AI. He received the CHI Academy honor for his work at the intersection of AI and human-computer interaction. He has been elected fellow of the National Academy of Engineering(opens in new tab) (NAE), the Association of Computing Machinery (opens in new tab)(ACM), Association for the Advancement of Artificial Intelligence(opens in new tab) (AAAI), the American Association for the Advancement of Science(opens in new tab) (AAAS), the American Academy of Arts and Sciences(opens in new tab), the American College of Medical Informatics(opens in new tab), and the American Philosophical Society(opens in new tab).Dr. Horvitz currently serves on the advisory boards of the Allen Institute for AI (opens in new tab)(Ai2) and Stanfords Institute for Human-Centered AI(opens in new tab) (HAI). He served as a member of the Presidents Council of Advisors on Science and Technology(opens in new tab) (PCAST), president of the AAAI, as a member of the Computer Science and Telecommunications Board(opens in new tab) (CSTB) and Computing Community Consortium(opens in new tab) (CCC), and on advisory committees for the National Science Foundation(opens in new tab) (NSF), National Institutes of Health(opens in new tab) (NIH), and Defense Advanced Research Projects Agency(opens in new tab) (DARPA).He received Ph.D. and M.D. degrees at Stanford University. Before moving into the role of Chief Scientific Officer, he served as director of Microsoft Research overseeing research labs in Redmond, Washington; Cambridge, Massachusetts; New York City, New York; Montreal, Canada; Cambridge, United Kingdom; and Bangalore, India. More information can be found on his home page(opens in new tab). A selected list of publications can be found here(opens in new tab).


 Speaker Profile

M.D., Ph.D., Co-Founder and CEO, Noetik

Biography
Ron Alfa is a physician scientist at the forefront of leveraging technology to tackle unmet therapeutic needs in medicine. He is Co-Founder and CEO of NOETIK, a next generation precision oncology company using multimodal foundation models pre-trained on large-scale human tumor data to discover cancer therapeutics. Prior to founding Noetik, Ron was Senior Vice President, Head of Research and acting-CSO at Recursion, where he led the companys scientific organizations and portfolio strategy. At Recursion, he led portfolio and platform builds across rare disease, neuroscience, oncology, and immunology, and was responsible for advancing multiple therapeutic programs from discovery to clinical development. Ron holds an MD and PhD from Stanford University School of Medicine, where he completed his doctoral work in Neuroscience, and has a MA in History of Medicine from UCL.


Talk
Foundation models for human biology
Foundation models for human biology


 Speaker Profile

MA, Chief Business Officer, GeneDx

Biography
Lisa Gurry is the Chief Business Officer at GeneDx, where she is leading the company through its next phase of growthadvancing data and information services across biopharma, health systems, and other partnersto accelerate the future of precision medicine. In this role, Lisa drives GeneDxs strategic business operations, partnerships, and data strategy, unlocking the full potential of GeneDx Infinity, the largest rare disease dataset. She also oversees marketing and communications. With deep expertise at the intersection of healthcare, technology, and data, Lisa has a proven track record of turning bold ideas into scaled businesses. She co-founded Truveta, serving as Chief Growth Officer, Chief Marketing Officer, and Chief Operating Officer. Earlier in her career, Lisa spent more than 20 years at Microsoft.


Talk
Unlocking Biopharma Solutions with AI-Powered Genomic Data
Powered by AI and millions of genomes linked to deep longitudinal phenotypic data, GeneDx delivers unparalleled rare-disease intelligence. This session will share how GeneDx partners with biopharma to turn genomic data into actionable solutionsaccelerating discovery and clinical trials, and advancing the next era of precision medicine.


 Speaker Profile

M.D., Endowed Professor, OHSU; co-Founder Pathomiq, PATHOMIQ

Biography
Dr. Shivaani Kummar is Associate CEO and interim Director, Knight Cancer Institute, Endowed Professor and Division Chief of Hematology and Medical Oncology, and co-Director of the Center of Experimental Therapeutics, Oregon Health Science University, Portland, Oregon, USA. Prior to joining OHSU in 2020, she was on faculty at Yale University Cancer Center, served as Head of Early Clinical Trials Development Office of the Director, Division of Cancer Treatment and Diagnosis, NCI, and was Professor and Director of the Phase 1 Clinical Research Program and Translational Oncology Program at Stanford University, California. She specializes in conducting pharmacokinetic and pharmacodynamic driven first-in-human trials tailored to make early, informed decisions regarding the suitability of novel agents for further clinical investigation. She has authored over 180 peer reviewed publications, 9 book chapters, and co-edited a book. She is the co-founder of Pathomiq, a company that has developed an AI platform to predict response to treatment.


 Speaker Profile

M.D.,Ph.D., Partner, Khosla Ventures

Biography
Alex's focus at Khosla Ventures is in biotechnology, healthcare, data science, and AIML.


 Speaker Profile

Ph.D., Co-Founder, Chairman, & CEO, Xaira Tx

Biography
Marc Tessier-Lavigne is co-founder, ChairmanCEO of Xaira Therapeutics. Previously,he held executive positions at Genentech, where he was chief scientific officer, and inacademia, where he served as president of The Rockefeller University and of StanfordUniversity, where he remains professor of Biology. He also served previously on thefaculty of the University of California, San Francisco, and was an investigator with theHoward Hughes Medical Institute. A Rhodes Scholar, Dr. Tessier-Lavigne has been aleader in understanding mechanisms that direct brain wiring. He has received numerousscientific awards, including the 2020 Gruber Neuroscience Prize, and has been electedto multiple scientific societies, including the US National Academy of Sciences and USNational Academy of Medicine; he is also an Officer of the Order of Canada. Dr. Tessier-Lavigne has co-founded two neuroscience startups, Renovis and Denali, and served onthe boards of Agios, Regeneron, Pfizer, Juno and Denali.


 Speaker Profile

Ph.D., Immunology Team Lead, CytoReason

Biography
Dr. Liat Dassa is an Immunology Team Leader at CytoReason, an Israeli techcompany developing AI for drug development. She oversees the team ofimmunologists and data annotators generating and ensuring the biologicalvalidity of the companys computational disease models. Liat completed herBSc and MSc in biomedical sciences at the Hebrew University where shegraduated magna cum laude and with honors, respectively. She went on tocomplete her doctorate in immunology there, focusing on the interaction ofviruses and tumor-associated bacteria with the immune system. Liat servedas soldier and commander in the Israeli Defense Forces 8200 intelligenceunit. She lives with her husband and two children in Modiin, Israel.


 Speaker Profile

M.D., Vice Chair of Research, Desai Sethi Urology Institute, U. of Miami

Biography
Sanoj Punnen, MD, MAS, completed his medical school at Queens University and urology residency at the University of Toronto in Canada. He then completed a uro-oncology fellowship and Masters in Clinical Research at the University of California, San Francisco. He is board-certified in both urology and uro-oncology. His primary research interest is in localized prostate cancer. Specifically, his work has evaluated imaging, molecular, and genomic markers that play a role in prostate cancer diagnosis and prognosis. He is also involved in outcomes and health service research on trends in the incidence and management of prostate cancer.


 Speaker Profile

M.D., Ph.D., Director, UI Holden Compre. Cancer Ctr.

Biography
Dr Mark E. Burkard, MD, PhD is the Director, UI Holden Comprehensive Cancer Center. He is also Professor and Associate Dean for Cancer Research in the Carver College of Medicine and C.E Block Chair of Cancer Research, Department of Internal Medicine, University of Iowa. Dr Burkard is a medical oncologist who specializes in the treatment of breast cancer and in precision oncology


 Speaker Profile

M.D.,Ph.D., Partner, Khosla Ventures

Biography
Alex's focus at Khosla Ventures is in biotechnology, healthcare, data science, and AIML.


Talk


Emerging Therapeutics Showcase:
Neosplice Therapeutics

 Speaker Profile

Ph.D., Professor, Harvard Public Health

Biography
John Quackenbush is Professor of Computational Biology and Bioinformatics in the Department of Biostatistics at the Harvard T.H. Chan School of Public Health. Trained in theoretical physics, he transitioned to genomics through a Human Genome Project fellowship, with subsequent appointments at the Salk Institute, Stanford University, and The Institute for Genomic Research, before joining Harvard in 2005. His research leverages biological data to understand how many small genetic effects combine to influence health and disease. Central to his work is modeling gene regulatory networks and characterizing how these networks vary across health states, by sex and gender, and between individuals. He has over 350 publications with more than 105,000 citations, and his NetZoo software tools are used. His honors include being named a White House Open Science Champion of Change (2013) and being elected to the National Academy of Medicine in 2022. He founded Genospace in 2012, which was acquired in 2017.


Talk
Embracing Biological Complexity to Understand Disease Drivers
Target Discovery: Beyond Genomics - Revealing Hidden Layers of Biology with AI


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