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 Session Abstract – PMWC 2026 Silicon Valley

Track 1 - March 4 9.00 A.M.-4.45 P.M.


Track Co-Chairs:
Gad Getz, Broad Institute
Alex Morgan, Khosla Ventures

PMWC Award Ceremony Honoree
• Greg Brockman, President & Co-Founder, OpenAI
• Steve Wozniak, Co-Founder, Apple

Keynote
• Vinod Khosla, Khosla Ventures

Target Discovery: Beyond Genomics – Revealing Hidden Layers of Biology with AI
• Keynote: Stephen Quake, CZ Biohub
• Aritro Nath, City of Hope
• Massa Shoura, Phinomics
• Omar Serang, DNAnexus

Illuminating Drug Discovery: AI Models That Learn From Biology
• Erwin Estigarribia, HEADLAMP Health

Harmonizing the Data Economy: Enabling AI Across Institutions and Therapeutic Areas
• Noah Nasser, Datma

Can AI Really Create the Next Blockbuster Drug?
• James Zou, Stanford

Interpretable AI for Biomarker Discovery: Accelerating Drug Development
• Chair: Rajat Roy, PATHOMIQ INC

Closing the Loop: AI in the Messy Middle of Drug Development
• Ari Caroline, Weave Bio
• Dina Katabi, Emerald / MIT

Is AI the New Drug?
• Michael J. Kahana, Nia Therapeutics

 Speaker Profile

Ph.D., Director, Cancer Genome Analysis & Professor of Pathology, MGH & Broad Inst.

Biography
Dr. Getz is an internationally acclaimed leader in cancer genomics and is pioneering widely used tools for analyzing cancer genomes. Dr. Getz is a Professor of Pathology at Harvard Medical School. He is the Director of Bioinformatics at the Massachusetts General Hospital (MGH) Cancer Center and Department of Pathology, and is an Institute Member of the Broad Institute of MIT and Harvard, where he directs the Cancer Genome Computational Analysis Group. He has published over 400 papers in prominent journals describing new methodologies to study cancer genomes that have identified new genes and pathways involved in different tumor types, mutational signatures, and tumor evolution.


 Speaker Profile

Ph.D., Co-Founder & CEO, Nia Tx

Biography
Dr. Michael Kahana is CEO and co-founder of Nia Therapeutics, which is developing an AI-guided closed-loop neurostimulation therapy for memory loss. During his 30-year academic career, Kahana published more than 200 scientific articles and won numerous awards for his pioneering research on the neural basis of human memory and for his contributions ot memory theory.


 Speaker Profile

Co-founder, CSO, Weave Bio

Biography
Ari is Cofounder and CSO at Weave Bio. Weaves native-AI regulatory platform helps life science companies to weave together data and documentation for all regulatory submissions, from pre-IND to NDABLA, directly from the source data and studies.Previously, Ari was the first Chief Analytics Officer at Memorial Sloan Kettering Cancer Center (MSK) where he drove pioneering efforts using clinical data to analyze patient outcomes. Aris team at MSK developed the first operational AI model to match patients to clinical trials. While at MSK, Ari also contributed to the creation of startups like Flatiron Health and Paige AI. In 2019, Ari cofounded Daat.AI which was acquired by Tempus AI, where Ari served as SVP of RWD.


 Speaker Profile

Ph.D., Assistant Professor, City of Hope

Biography
Dr. Nath is a cancer biologist with expertise in both experimental and computational biology. At City of Hope, Dr. Nath leads a collaborative research team that investigates the potential of AIML in enhancing cancer patient outcomes. Through the integration of bioinformatics and AIML tools, his research aims to unravel the underlying mechanisms of tumor progression and establish cutting-edge biomarkers for improving the clinical outcomes of patients with cancer. His research employs multi-omics approaches to identify the drivers of tumor evolution and the subsequent development of drug resistance. Dr. Nath aspires to translate research findings into clinical impact, notably contributing to upcoming clinical trials in lung and breast cancer that will implement novel AI-guided biomarkers. Dr. Nath currently is a principal investigator (PI) of an ARPA-H grant, an NIH U01 grant, a PHASE ONE foundation grant, a JKTG foundation grant, and co-investigator of an ARPA-H and California Institute for Regenerative Medicine (CIRM) grant.


 Speaker Profile

M.D., Founder, Khosla Ventures

Biography
Vinod Khosla is an entrepreneur, investor, and technology fan. He is the founder of KhoslaVentures, focused on impactful technology investments in software, AI, robotics, 3Dprinting, healthcare and more. Mr. Khosla was a co-founder of Daisy systems and foundingCEO of Sun Microsystems where he pioneered open systems and commercial RISCprocessors. One of Mr. Khoslas greatest passions is being a mentor to entrepreneurs,assisting entrepreneurs and helping them build technology-basedbusinesses. Mr. Khosla isdriven by the desire to make a positive impact through technology to reinvent societalinfrastructure and multiply resources. He is also passionate about Social Entrepreneurship.Vinod holds a Bachelor of Technology in Electrical Engineering from IIT, New Delhi, aMaster's in Biomedical Engineering from Carnegie Mellon University and an MBA from theStanford Graduate School of Business.


Talk
TBD
TBD


 Speaker Profile

M.D.,Ph.D., Partner, Khosla Ventures

Biography
Alex's focus at Khosla Ventures is in biotechnology, healthcare, data science, and AIML.


 Speaker Profile

PMWC LUMINARY AWARD
Transforming science and medicine with Generative AI

President and Co-Founder, OpenAI

Biography
Greg Brockman is the President and Co-Founder of OpenAI, where he currently leads the companys Scaling organizationfocused on expanding the technical infrastructure and systems needed to support OpenAIs rapid growth and increasingly capable models. He has played a central role in shaping OpenAIs mission and in bringing transformative technologies like ChatGPT, DALLE, and Codex to millions of people and businesses around the world.Before OpenAI, Greg was the CTO of Stripe, where he built and led the engineering team during a period of rapid scale. He studied mathematics at Harvard and computer science at MIT before leaving to pursue a career at the forefront of technology.Greg is a technologist and builder, deeply invested in ensuring artificial general intelligence is developed safely and benefits all of humanity. He regularly speaks on the future of AI, responsible deployment, and the infrastructure powering the next generation of intelligent tools.


Talk
Fireside Chat
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 Speaker Profile

Ph.D., Dual PhD., CEO and CSO, Phinomics

Biography
Massa Shoura is the CEO and CSO of Phinomics, an innovative company transforming precision medicine by unlocking the potential of circular DNA and integrating genomics with advanced AI. With dual PhDs in Molecular Biology and Biomedical Engineering, Massa has over a decade of expertise in DNA topology, biophysics, and genomics. During her postdoctoral fellowship at Stanford University in Nobel Laureate Dr. Andrew Fires lab, she developed groundbreaking tools for isolating and characterizing circular DNA, earning prestigious fellowships, including the Arnold O. Beckman Fellowship, and securing two granted patents. As a Forbeck Scholar, she advanced cancer genomics by uncovering the role of oncogenic circular DNA amplification. She also spearheaded the sequencing and publication of Pfizer and Moderna COVID-19 vaccine mRNAs, showcasing her commitment to global health. At Phinomics, Massa leads the development of first-in-class precision oncology solutions through the Circulome Atlas, a transformative platform providing unparalleled insights into cancer etiology, progression, and therapeutic resistance.


 Speaker Profile

CEO and President, PATHOMIQ

Biography
Rajat Roy is a serial entrepreneur and technology leader serving as CEO Co-founder of PathomIQ Inc. pathomiq.com With expertise spanning enterprise AIML, diagnostics, and health tech, he has led two prior successful startup exits. pathomiq.comUnder his leadership, PathomIQ has advanced its AI-powered diagnostic platform (PathomIQ_PRAD) for prostate cancer in collaboration with Myriad Genetics. myriad.gcs-web.com+1 The platform applies machine learning to analyze digital pathology images, supporting predictions of patient outcomes, treatment response, and genotypic features in 12 days. Haynes Boone+1Rajat holds educational credentials from Stanford University, and is based in the San Francisco Bay Area.


 Speaker Profile

EVP and GM, Regulatory and Government Solutions, DNAnexus

Biography
Omar has decades of experience designing global cloud platforms pioneering the use of collaborative feedback networks to solve challenging information extraction problems. He is the Principal Architect of precisionFDA.gov, the FDA cloud platform that is transforming the regulatory research and review process for precision drugs and devices. Prior to DNAnexus, Omar managed operations for the AWS Elastic Compute Cloud when single regions were topping the one-million server mark. Previously, he led platforms for a Twitter search engine at Topsy Labs, and crowd-sourced messaging security at Cloudmark. Omar received his Bachelor of Science in Chemistry from UC Berkeley.


 Speaker Profile

President, Chairman, & Co-Founder, OpenAI

Biography
Greg Brockman is the President and Co-Founder of OpenAI, where he currently leads the company’s Scaling organization—focused on expanding the technical infrastructure and systems needed to support OpenAI’s rapid growth and increasingly capable models. He has played a central role in shaping OpenAI’s mission and in bringing transformative technologies like ChatGPT, DALL·E, and Codex to millions of people and businesses around the world. Before OpenAI, Greg was the CTO of Stripe, where he built and led the engineering team during a period of rapid scale. He studied mathematics at Harvard and computer science at MIT before leaving to pursue a career at the forefront of technology. Greg is a technologist and builder, deeply invested in ensuring artificial general intelligence is developed safely and benefits all of humanity. He regularly speaks on the future of AI, responsible deployment, and the infrastructure powering the next generation of intelligent tools.


 Speaker Profile

M.D., Founder, Khosla Ventures

Biography
Vinod Khosla is an entrepreneur, investor, and technology fan. He is the founder of KhoslaVentures, focused on impactful technology investments in software, AI, robotics, 3Dprinting, healthcare and more. Mr. Khosla was a co-founder of Daisy systems and foundingCEO of Sun Microsystems where he pioneered open systems and commercial RISCprocessors. One of Mr. Khoslas greatest passions is being a mentor to entrepreneurs,assisting entrepreneurs and helping them build technology-basedbusinesses. Mr. Khosla isdriven by the desire to make a positive impact through technology to reinvent societalinfrastructure and multiply resources. He is also passionate about Social Entrepreneurship.Vinod holds a Bachelor of Technology in Electrical Engineering from IIT, New Delhi, aMaster's in Biomedical Engineering from Carnegie Mellon University and an MBA from theStanford Graduate School of Business.


 Speaker Profile

PMWC PIONEER AWARD
Pioneer of personal computing who engineered the foundation for today’s AI revolution.

Co-Founder, Apple

Biography
A Silicon Valley icon, technology entrepreneur, and philanthropist for more than four decades, Steve Wozniak has helped shape the computing industry through his design of Apples first line of products the Apple I and II and his influence on the Macintosh. In 1976, Wozniak and Steve Jobs co-founded Apple Computer Inc. with Wozniaks Apple I, followed by the Apple II, which helped launch the personal computer revolution. He is listed as the sole inventor on four Apple patents.After completing his degree in electrical engineering and computer science at UC Berkeley, Wozniak founded Unuson, producer of the US Festivals a landmark fusion of technology and music. His achievements have been recognized with the National Medal of Technology from President Ronald Reagan, induction into the National Inventors Hall of Fame, and the Heinz Award for Technology, the Economy and Employment.A committed advocate for education and innovation, Wozniak has championed technology access in schools and supported institutions such as the Electronic Frontier Foundation, the Tech Museum of Innovation, and the Childrens Discovery Museum of San Jose. He is the author of the New York Times best-selling autobiography iWoz and continues to advance technology education as co-founder of Woz U and Efforce, a blockchain-based sustainability platform.


 Speaker Profile

Ph.D., Co-Founder & CSO, BioSymetrics (Lunai)

Biography
Dr. Musso has a background in molecular genetics (PhD), and did post-doctoral work at Harvard Medical School and Brigham and Women's Hospital on computational and developmental biology. He spent time at a start-up working on real-time machine learning, before joining with others to start BioSymetrics with the aim of tackling the specific challenges of working with biomedical data. He was named one of the top 100 leaders in AI and drug discovery, has authored over 30 peer reviewed publications on AIML and biology.


Talk
Closing the loop: Coupling AI with In vivo validation
AI models are accelerating target and compound discovery, but translation remains a bottleneck. We present a closed-loop platform integrating predictive AI with high-throughput in vivo validation using disease models relevant to neurological disease. Case studies demonstrate how this approach improves hit prioritization, enhances biological relevance, and increases success rates in drug development.


 Speaker Profile

Ph.D., CEO, Consort Partners

Biography
Dr. Georgescu spearheads Vivodyne's vision of reshaping therapeutics development. The loss of translation between animal studies and human trials compelled him to co-found Vivodyne in 2020 and create an entirely new platform from the ground up. With a Ph.D. from Dr. Huh's esteemed organ-chip research group at the University of Pennsylvania, his expertise lies in human-tissue engineering, robotics, and machine learning. His prior achievements include sending lab-grown tissues with NASA to space and developing DNA synthesis chips that remain industry staples to this day.


 Speaker Profile

Ph.D., CSO & Co-Founder, Adaptive Biotech

Biography
Harlan Robins is a CoFounder of Adaptive Biotechnologies, a commercial stage biotech company that aims to translate the genetics of the adaptive immune system into clinical products to diagnose and treat disease. Prior to cofoundingconfounding Adaptive, Harlan served in various roles at the Fred Hutchinson Cancer Research Center (FHCRC) in the Computational Biology Program, including Assistant Faculty Member, Associate, and Full Member and Head of the program. Interested in the mathematics behind genetics and observing the potential utility of high level mathematics to study problems in the biological sciences, Harlan took a postdoctoral appointment at the Institute for Advance Study in Princeton under famed biologist Dr. Arnold Levine. With Dr. Levine, he concentrated on developing bioinformatic algorithms for micro RNA targets and bacterial genome analysis, a precursor to his faculty appointment at FHCRC in the Computational Biology Group, Public Health Sciences and Human Biology Divisions.


 Speaker Profile

Ph.D., CEO, Numenos

Biography
Vitalay Fomin, Ph.D.,CEO of Numenos AI, is an award-winning data scientist at RocheGenentech specializing in biomarker and reverse translation drug discovery


Talk
CURE AI provides efficacy signal from single arm trials
We developed a novel foundation model that is biologically aware capable of using single arm trials to identify optimal indication, patient population and drug combination and optimizes each asset for maximal clinical trial success


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