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 Session Abstract – PMWC 2027 Silicon Valley

Track 4: Integrated PM - Jan 28 9.00 A.M.-5.00 P.M.


Track Chair:
Burns Blaxall

PMWC Award Ceremony
• Euan Ashley, Stanford
• Jeffrey R. Balser, Vanderbilt
• Howard J. Jacob, Abbvie

Precision Medicine at Scale: Lessons from Vanderbilt
• Jeffrey R. Balser, Vanderbilt

From First Patient to a Million Genomes
• Chair: Howard J. Jacob, Abbvie
• Jeffrey R. Balser, Vanderbilt
• Euan Ashley, Stanford

Keynote: AI and Data-Driven Individual Health- Optimizing Wellness, Preventing Disease and Empowering Precision Medicine
• Lee Hood, Phenome Health

Keys to Successful Implementation of a Precision Medicine Program
• Chair: Howard McLeod, GeneDx
• Kevan Simms, Ochsner Health
• David Glazer, Verily
• Mark Atalla, HHS
• Susanne Munksted, Diaceutics

Precision Cardiology at Scale: Implementing Genomics Beyond Oncology
• Chair: Damon Hostin, Illumina
• David E. Lanfear, Henry Ford Health
• onit Yarden, NIH/NHLBI

Precision Medicine at Scale: Lessons from a Statewide Genomic Initiative
• Chair: Premal Shah, MyOme
• Niall Lennon, Broad Clinical Labs
• Oliver Hampton, Southern Research

Integrating Multi-Modal Biology into Precision Care Pathways: A Systems Framework for Scalable Implementation
• K V Venkatesh, IIT Mumbai

From Multi-Omics to Clinical Action: Making It Work at UCSF
• Marina Sirota, UCSF

From $/Gb to Outcomes: Simplifying Genomics for Health Systems
• Jacob Thaysen, Illumina

Achieving Comprehensive Precision Medicine
• Chair: Burns Blaxall
• Trish Brown, GeneDx
• Eric Green, Illumin
• Daryl Pritchard, Personalized Medicine Coalition
• Ora Gordon, Providence Health
• Sarah Hersey, BMS

 Speaker Profile

Ph.D., Interim Director at UCSF BCSHI and Professor, UCSF

Biography
Marina Sirota is a Professor and Interim Director of UCS Fs Bakar Computational Health Sciences Institute. Previously, she served as a Senior Research Scientist at Pfizer, focusing on precision medicine. She earned her PhD in Biomedical Informatics from Stanford University. With 20 years of experience and over 170 publications, Dr. Sirota develops computational integrative methods for diagnostics and therapeutics, specializing in womens health. Her laboratory is funded by the NIA, NLM, NIAMS, Pfizer, and the March of Dimes. A 2017 A MIA Young Investigator Award recipient, she leads the UCSF March of Dimes Prematurity Research Center and co-directs ENACT, a precision medicine center for endometriosis. Dr. Sirota also founded UCS Fs AI4ALL program, which introduces high school girls to the applications of AI and machine learning in biomedicine.


 Speaker Profile

Ph.D., Senior Data Scientist, Novo Nordisk

Biography
Innovative Senior Data Scientist with over 10 years of leadership experience in biomarker discovery, advanced analytics for drug development, clinical data science and AI implementation. Proven expertise in integrating multi-modal data, deploying AI-driven solutions across clinical research environments, and fostering strategic collaborations internally and externally to deliver high-impact results. Recognized for excellence in aligning scientific expertise with business needs to drive actionable insights and improve decision-making. In her current role, she helps Novo Nordisk's longevity task force to understand the longevity potential of its assets, design longevity-focused clinical trials, and engage with regulatory authorities to define longevity outcomes. She also analyses omics data from RCTs to understand drug mode of action and identify responders to treatment.


 Speaker Profile

M.D., CMO & SVP, Emblem Health

Biography
Dr. Daniel Knecht, M.D., M.B.A., is the Chief Medical Officer and Senior Vice President of EmblemHealth, where he leads clinical strategy to improve health outcomes for approximately 3 million New Yorkers. Previously, he served as Chief Clinical Innovation Officer at CVS Caremark, focusing on enhancing patient outcomes and managing healthcare costs. Before CVS, Dr. Knecht directed clinical strategy and medical policy initiatives at Aetna, where he implemented successful quality improvement projects, including addressing the opioid crisis and gene therapy reimbursement strategies. Dr. Knecht is a Fulbright Scholar and an accomplished academic. He graduated cum laude from Dartmouth College with a degree in Biochemistry and Molecular Biology and earned his joint M.D.,M.B.A. from Weill Cornell Medical College and Johnson Graduate School of Management, where he was awarded the Lee Family Scholarship. Dr. Knecht is also a practicing hospitalist at Mount Sinai West in New York City, where he serves as an Assistant Clinical Professor. In addition, he contributes his expertise to public health as a board member of the CUNY School of Public Health Foundation and as an advisor to Monogram Health, focusing on advancing care models for chronic kidney disease. Dr. Knecht’s innovative contributions to healthcare have earned him widespread recognition, including being named one of Modern Healthcare’s 40 Under 40 in February 2024. His career reflects a deep commitment to bridging clinical care and healthcare innovation, positioning him as a transformative leader in the industry.


 Speaker Profile

M.D., Chief Information and Digital Officer, Associate Dean, Clinical Professor of Medicine, Stanford

Biography
Michael A. Pfeffer, MD, FACP serves as Chief Information and Digital Officer and Associate Dean for Stanford Health Care and Stanford University School of Medicine. Michael oversees Technology and Digital Solutions (TDS), responsible for providing world class technology solutions to Stanford Health Care and School of Medicine, enabling new opportunities for groundbreaking research, teaching, and compassionate care across two hospitals and over 150 clinics. TDS supports Stanford Medicines mission to improve human health through discovery and care and strategic priorities to be value focused, digitally driven, and uniquely Stanford. Michael is a Clinical Professor in the Department of Medicine and Division of Hospital Medicine with a joint appointment in the center for Biomedical Research (BMIR) in Stanford University School of Medicine.


 Speaker Profile

M.D., Chair of Personalized Medicine, Endeavor Health

Biography
Peter Hulick, MD, a clinical geneticist and chair of personalized medicine at Endeavor Health, helps patients understand how genomic information can inform care and improve health outcomes. With a career rooted in genetics since high school, he works to integrate genomic data into everyday decision-making for patients and clinicians. Dr. Hulick focuses on risk assessment, early detection and treatment guidance by combining science, patient context and team collaboration. He also leads efforts to make genomic care more accessible across the health system.


 Speaker Profile

PMWC LUMINARY AWARD
Translated renin-angiotensin biology into life-saving cardiovascular therapies

M.D., President, National Academy of Medicine

Biography
Victor J. Dzau is a physician-scientist and global leader whose career bridges discovery, health system leadership, and national medicine policy. His cardiovascular research on the renin-angiotensin system helped shape modern understanding of vascular disease and contributed to the development and use of lifesaving ACE inhibitor therapies. As president of the National Academy of Medicine, he led major initiatives in precision health, human genome editing, clinician well-being, pandemic preparedness, global health, and equitable innovation. He previously served as Chancellor for Health Affairs at Duke University and President and CEO of Duke University Health System, and held senior academic leadership roles at Stanford and Harvard. In 2026, Dzau returned to Duke as James B. Duke Distinguished Professor of Medicine, Chancellor Emeritus for Health Affairs, and Director of the Mandel Center for Hypertension and Atherosclerosis. His career reflects the PMWC mission: turning science into systems that improve lives at scale worldwide today everywhere.


 Speaker Profile

M.D., Operating Partner, Khosla Ventures

Biography
Dr. Paz has served as an executive and board member across providers, payers, and med-tech. He was EVPCMO of CVS Health Aetna; ChancellorCEO of Ohio State Wexner Medical Center; and CEO of Penn State Health and Stony Brook Univ Medicine. He sits on the boards of Envision Healthcare and Research America and previously served on Select Medical, USPI, Vyteris, and seven health-system boards. He advises Curai Health and previously advised Johnson Johnson and USPI. He has served on committees of the National Academy of Medicine and the National Academies. A former medical school dean and investigator in sepsis, A RDS, and medical devices, he has authored over 100 publications. Dr. Paz earned his BA and MD at the University of Rochester and an MS in life science engineering at Tufts, trained at Northwestern, and completed fellowships at Johns Hopkins in pulmonary and critical care and in environmental health sciences.


 Speaker Profile

M.D., Chairman, Oracle

Biography
As Chairman of Oracle Health, David Feinberg, MD, is committed to making healthcare more accessible, affordable, and equitable. His work advances thought leadership and strategy related to unleashing the healing power of data through an open and connected healthcare ecosystem. Previously, David served as president and CEO of Cerner, now Oracle Health, where he led teams focused on delivering tools and technology to improve the patient and caregiver experience. David built his early career as a pediatric psychiatrist around helping children and families. He served as president and CEO of both UCLA Health and Geisinger Health prior to assuming leadership of Google Health in early 2019. He earned his MD from Chicago Medical School in 1989, finishing at the top of his class and is a member of the Alpha Omega Alpha Medical Honor Society. He also holds an economics degree from the University of California-Berkeley and an MBA from Pepperdine University.


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