Speaker Profile

MD, PhD, Co-Director of Cancer Genetics and Epigenetics, Johns Hopkins U.

Biography
Dr. Velculescu led the first genome wide sequence analysis in human cancers, identifying key genes and pathways dysregulated in tumorigenesis. He developed methods for global gene expression analyses and coined the word transcriptome" to describe the patterns that could now be obtained in cancer and other cells. These analyses identified a variety of genes not previously known to be involved in neoplasia, including PIK3CA as one of the most highly mutated genes in human cancer. His team's discoveries have led to new FDA approved therapies against PI3K and IDH1, and diagnostic tests for comprehensive tumor profiling. More recently, his group has created noninvasive machine learning liquid biopsy approaches for early detection and monitoring of cancer patients. His work has provided new paradigms for understanding human cancer that have benefited patients worldwide. He has been a Founder and CoCEO of Personal Genome Diagnostics and is Founder and CEO of Delfi Diagnostics.


 Session Abstract – PMWC 2024 Silicon Valley

Track 4 - January 25 9.00 A.M.-4.30 P.M.


Track Chair: Laura J. van 't Veer, UCSF

  • PMWC 2024 Award Ceremony
    Pioneer Honoree: David Sidransky, Johns Hopkins
    Pioneer Honoree: Helmy Eltoukhy
    Pioneer Honoree: AmirAli Talasaz, Guardant Health
  • Utilities of Liquid Biopsy in Biomarker Testing
    - Laura Vent Veer, UCSF
  • Status Quo of Clinical Liquid Biopsy (PANEL)
    Chair: Helmy Eltoukhy, Guardant Health
    - Sadakatsu Ikeda, Tokyo Medical University
    - Heather Parsons, Dana-Farber Cancer Institute
    - Sanjay Popat, The Royal Marsden
  • Liquid Biopsy for Health Monitoring and Disease Prevention (PANEL)
    Chair: Anne-Renee Hartman, Adela Bio
    - AmirAli Talasaz, Guardant Health
    - Heather Parsons, Dana-Farber Cancer Institute
    - Mary Pat Lancelotta, Adaptive Bio
    - Sylvia Katina Plevritis, Stanford
  • Multi-Cancer Early Detection Through Multi-Biomarker Class Liquid Biopsy Testing (PANEL)
    Chair: Tom Beer, Exact Sciences
    - Wendy Rubinstein, National Cancer Institute
    - Sheila D. Walcoff, Goldbug Strategies LLC
  • Keynote: Pioneering Liquid Nucleic Acids Tumor Fragments in Health and Diseases
    - David Sidransky, Johns Hopkins
  • New Approaches in Liquid Biopsy (PANEL)
    Chair: Victor Velculescu, Johns Hopkins
    - David Sidransky, Johns Hopkins
    - Dan Laudau, NY Genome Center
    - Daniel De Carvalho, University of Toronto
  • Global Implications: A scalable Liquid Biopsy for HPV-related Cervical Cancer (PANEL)
    Chair: Debra Fraser-Howze, D. Fraser Associates
    - Belinda Nedjai, Wolfson Institute of Population Health
    - Elisabeth Adams, Aquarius Population Health Limited
  • NCI Showcase
    - Xiaohui Ni, Early Dx
    - Daniel Kim, UCSC

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