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 Speaker Profile

Ph.D., Director of Heart Failure Unit, Rambam

Biography
Dr. Oren Caspi, MD, PhD is Director of the Heart Failure Unit and Head of the Cardiovascular Research and Innovation Center at Rambam Health Care Campus, and leads the Laboratory for Cardiovascular Precision Medicine at the Rappaport Faculty of Medicine, Technion.An internationally recognized clinician-scientist, leading the young israeli national academy for science in medicine. Dr. Caspi works at the forefront of heart failure, regenerative cardiology, and data-driven cardiovascular medicine. He was among the pioneers to demonstrate functional myocardial recovery using human stem cellderived cardiomyocytes. His work advanced multicellular organoid technologies and led to the development of the first human vascularized 3D cardiac tissue, earning multiple prestigious awards.Dr. Caspi founded Rambams Heart Failure Unit and LVAD program and leads institutional initiatives in digital health and cardiac rehabilitation. His current research integrates stem cell biology, organoids, machine learning, and causal inference to advance precision drug discovery, disease modeling, and heart failure care.


 Session Abstract – PMWC 2026 Silicon Valley

Track 4: Integrated PM - March 5 9.00 A.M.-5.00 P.M.


Track Chair:
Burns Blaxall

PMWC Award Ceremony
• Euan Ashley, Stanford
• Jeffrey R. Balser, Vanderbilt
• Howard J. Jacob, Abbvie

Precision Medicine at Scale: Lessons from Vanderbilt
• Jeffrey R. Balser, Vanderbilt

From First Patient to a Million Genomes
• Chair: Howard J. Jacob, Abbvie
• Jeffrey R. Balser, Vanderbilt
• Euan Ashley, Stanford

Keynote: AI and Data-Driven Individual Health: Optimizing Wellness, Preventing Disease and Empowering Precision Medicine
• Lee Hood, Phenome Health

Keys to successful implementation of a Precision Medicine Program
• Chair: Howard McLeod, GeneDx
• Kevan Simms, Ochsner Health
• Chris Lunt, NIH

Key players in successful implementation – Beyond Oncology
• Chair: Damon Hostin, Illumina
• Shaista Malik, UC Irvine
• David E. Lanfear, Henry Ford Health
• Oren Caspi, Rambam

Precision Medicine at Scale: Lessons from a Statewide Genomic Initiative
• Chair: Premal Shah, MyOme
• Niall Lennon, Broad Clinical Labs

Integrating Multi-Modal Biology into Precision Care Pathways: A Systems Framework for Scalable Implementation
• K V Venkatesh, IIT Mumbai

Fireside Chat: From $/Gb to Outcomes: Simplifying Genomics for Health Systems
• Jacob Thaysen, Illumina

Achieving Comprehensive Precision Medicine
• Chair: Burns Blaxall
• Trish Brown, GeneDx
• Charles Sailey, Molecular Testing Labs
• Sarah Hersey, BMS

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