Speaker Profile
PMWC PIONEER AWARD
Co-developed liquid biopsy methods and CancerSEEK for multicancer early detection
Ph.D., Director of Translational Genetics, Johns Hopkins U.
Biography
Nickolas Papadopoulos is a pioneer in cancer genetics and multi-cancer early detection. At Johns Hopkins, he helped define the genetic basis of hereditary nonpolyposis colorectal cancer, now central to understanding mismatch repair defects and inherited cancer risk. He later helped lead the development of CancerSEEK, a blood-based multi-analyte test combining circulating tumor DNA mutations and protein biomarkers to detect multiple common cancers, including cancers with no routine screening option.
As a senior leader of DETECT-A, he helped move multi-cancer early detection beyond technical promise into a prospective interventional screening study in nearly 10,000 asymptomatic women. His work has helped shift liquid biopsy from tumor profiling toward earlier detection, clinical localization, and real-world implementation, a central frontier in precision oncology.
Talk
Session Abstract – PMWC 2027 Silicon Valley
Davos of Precision Medicine
PMWC 2027 Program
January 27–29, 2027 · Santa Clara Convention Center
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In a few words.
PMWC is indeed The Davos of Biotech
PMWC Hall of Impact
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