Speaker Profile
Ph.D., Professor, BC Children’s Hospital Research Inst.
Biography
Megan Levings, Ph.D., is a Professor at the University of British Columbia, an investigator at BC Children’s Hospital Research Institute, and Canada Research Chair in Engineered Immune Tolerance. She is internationally recognized for research on regulatory T cells, or Tregs, and their potential as living medicines for immune-mediated disease. Her laboratory studies the biology of human Tregs, mechanisms that maintain immune tolerance, and ways to engineer or expand these cells for therapeutic use. The work spans transplantation, autoimmunity, inflammatory disease, and cell-therapy manufacturing, with a strong emphasis on translating mechanistic immunology into clinical strategies. Dr. Levings has contributed to the development and immune monitoring of early clinical Treg therapies and to technologies designed to improve their specificity, stability, and function. She also leads the Childhood Diseases research theme at BC Children’s. Her research seeks to replace broad immunosuppression with precise, durable immune regulation by harnessing and engineering the body’s own tolerance mechanisms.
Session Abstract – PMWC 2027 Silicon Valley
Track Chair:
Mark Genovese, Eli Lilly
PMWC Award Ceremony
• Miriam Merad, Mount Sinai (Luminary)
• Jeffrey A. Bluestone, UCSF (Luminary)
Featured Speakers
• Miriam Merad, Mount Sinai
• Jeffrey A. Bluestone, UCSF
• Gallia Levy, Gilead
• Marcela V. Maus, Harvard
• Nick Wilson, Biogen
• Megan Levings, BC Children's Hospital Research Institute
• Min Bao, Kali Therapeutics
• Purvesh Khatri, Stanford
• Heleen Scheerens, Genentech
• Pascal Geldsetzer, Stanford
• Dan Littman, NYU
• Anne Kasmar, Parexel
Macrophages Across Inflammation, Cancer & Aging
Master regulators of tissue health and disease across precision immunology.
Immune Reset in Autoimmune Disease
CAR-T, in vivo CAR, and the pursuit of durable remission.
Beyond Broad Immunosuppression
Tolerance, Tregs, and disease-modifying approaches.
Turning Biomarkers on Their Head
What we can measure before we can reliably predict response.
Precision Immunology in Clinical Development
Trial enrichment, deeper endpoints, response prediction, and regulatory strategy.
The Microbial Roots of Autoimmunity
Chronic infection, dysbiosis, and microbial signals shaping disease.
Davos of Precision Medicine
PMWC 2027 Program
January 27–29, 2027 · Santa Clara Convention Center
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PMWC is indeed The Davos of Biotech
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