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 Speaker Profile

Ph.D., VP, Science Policy, Friends of Cancer Research

Biography
Mark Stewart works at Friends of Cancer Research, a Washington, DCbased organization that brings together partners across healthcare to drive advances in science, policy, and regulation that accelerate the development of cancer therapies and diagnostics. At Friends, he leads collaborative projects that create frameworks for incorporating novel clinical trial endpoints, advancing ctDNA and liquid biopsy applications, integrating real-world evidence, and applying innovative designs to make trials more efficient and representative. His work also explores emerging technologies such as AI-based tools to enhance oncology drug development, clinical trial design, and data interpretation. Through multi-stakeholder partnerships with regulators, academia, industry, and patient groups, he helps develop consensus-driven solutions that overcome barriers in drug development. These efforts have informed national policy discussions, contributed to regulatory innovation, and translated promising innovations into meaningful progress for people with cancer.


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 Session Abstract – PMWC 2027 Silicon Valley

Track 1: Next-Gen Tx - Jan 28 9.00 A.M.-5.00 P.M.


Track Chair:
Ira Mellman, Medici Therapeutics

PMWC Award Ceremony
• Jedd D. Wolchok, Weill Cornell Medicine
• Suzanne Topalian, Johns Hopkins
• Levi Garraway, Roche

Keynote: Future Breakthroughs in Immuno-Oncology: New Targets, Modalities & Combinations
• Levi Garraway, Roche

Checkpoint 2.0 in Practice: PD-1+VEGF Wins, Resistance Salvage & Biomarker Gates
• Chair: Anne Kasmar, Parexel
• Jedd D. Wolchok, Weill Cornell Medicine
• Roy S. Herbst, Yale
• Nathan Fowler, BostonGene

Immunotherapy with Personalized Cancer Vaccines: Who, When, How Fast?
• Chair: Suzanne Topalian, Johns Hopkins
• Tal Zaks, Orbimed
• Lelia Delamarre, Genentech

The Next Era: Neutralizing On-Target, Off-Tumor Effects by Turning Cancer Against Itself
• Cyriac Roeding, Earli

Fireside Chat: Immune Tolerance to Cure, A Conversation With...
• Lee Hood, Institute for Systems Biology
• Mary E. Brunkow, Institute for Systems Biology

ADCs in the Checkpoint Era: Who Benefits, What to Combine, What to Avoid
• Chair: Shreya Badhrinarayanan, Pfizer
• Gerold Meinhardt, Daiichi Sankyo
• Vadim Koshkin, UCSF

Strategic IP Management in Cell and Gene Therapy: Navigating Legal and Practical Challenges
• Janet Xiao, Morrison & Foerster LLP

Targeting the Tumor Microenvironment (TME) in Practice: Biomarkers & Combos
• Chair: Ira Mellman, Medici Therapeutics
• Dmitry Gabrilovich, AstraZeneca
• Jennifer Mataraza, Novartis
• Nathan Fowler, BostonGene
• Christine Moussion, Genentech

Future Breakthroughs in TME Reprogramming: New Modalities, Smarter Delivery & Overcoming Resistance
• David Kirn, ReIGNITE
Radiopharmaceutical Therapy: New Targets, Isotopes, and Challenges
• Chair: William Oh, Yale
• Munir Ghesani, United Theranostics
• Sandy Srinivas, Stanford
• Anna Karmann, AdvanCell

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