Speaker Profile
Ph.D., Chief Scientific Officer, Co-Founder, Vevo Tx
Biography
At Vevo, Johnny Yu is focused on scaling its single-cell genomics platform, Mosaic, for discovery of novel therapeutics. Recently, Vevo applied Mosaic to generate the world's largest single-cell RNA sequencing atlas of 100M cells named Tahoe-100. Vevo continues to push the limits of single-cell data generation with the aim of becoming the world's first pharmaceutical company built on single-cell technologies. Before co-founding Vevo, Johnny Yu trained at UCSF with Dr. Hani Goodarzi and Dr. Kevan Shokat where he built the foundations for Mosaic which enables pan-cancer in-vivo screening. Previous to that, he worked at the Broad Institute and Biogen Idec.
Talk
Tahoe-100M surpasses all publicly available single-cell data and contains 60,000 drug perturbation experiments across 1200 drug treatments and 50 cancer models. It is the first dataset of its kind and will enable machine learning and AI models to rapidly scale in the genomics space.
Session Abstract – PMWC 2025 Silicon Valley
Track Chair:
Gad Getz, Broad Institute
- PMWC 2025 Luminary Award
Luminary Honoree: Jensen Huang, Nvidia
- Continued Jensen Huang, Nvidia
- Predictive Modeling for Drug Development
- Luca Emili, InSilicoTrials
- Knowledge Graphs, LLMs & Foundation Models for Enhanced Drug Development
- Janusz Dutkowski, Data4Cure
- Paul Rejto, Pfizer
- PMWC Showcase
- Peter Ellman, Certis Oncology
- Beyond LLMs: Harnessing Advanced AI Models for Genomics and Transcriptomics (PANEL)
Chair: Gad Getz, Broad Institute
- Yasin Şenbabaoğlu, CZ Biohub San Francisco
- Orly Alter, PrismAI
- Nicolo Fusi, Microsoft - Empowering AI in Precision Medicine with Federated Data Platforms
- Noah Nasser, Datma
- Advancing Global Health through Data Sharing: Practical Strategies and Success Stories (PANEL)
Chair: Luca Foschinii, Sage Bionetworks
- Peter Goodhand, GA4GH
- Karen Miga, UCSC
- Philip Awadalla, Ontario Institute for Cancer Research
- Driving Drug Discovery With Low-cost Foundational Omics Datasets
- Gilad Almogy, Ultima Genomics
- Johnny Yu, Vevo Therapeutics
- Stacie Calad-Thomson, NVDIA - Enabling Targeted Precision Drug & Gene Delivery with Predictive AI
- Andre Watson, Ligandal Inc.
- Quantum Leap: The Future of AI and Machine Learning with Quantum Computing
- Matthias Troyer, Microsoft
