Speaker Profile
M.D., Professor and Division Chief of Neuro-Oncology, UCSF
Biography
Dr. de Groot's broad clinical and laboratory experience enables effective translation of novel therapies into the clinic for the treatment of patients with primary brain tumors. He has significantly contributed to the clinical development of antiangiogenic, molecularly targeted and immunotherapy treatments for glioblastoma and regularly advise companies on such agents in development. He has been the PI of over 40 clinical trials and collaborator on over 80 other studies He is developing next generation trials using novel drug combinations and interventional techniques including blood brain disruption using laser ablation and focused ultrasound.
Session Abstract – PMWC 2025 Silicon Valley
Track Chair: Maggie Chapman, Labcorp
- Cross-Application of Oncology Drugs in Rare Diseases
- Razelle Kurzrock, Medical College of Wisconsin
- PMWC 2025 Award Ceremony
Luminary Honoree: David R. Liu, Broad Institute & Crystal Mackal, Stanford University
Pioneer Honoree: Drew Weissman, Penn Medicine
- Keynote: Base Editing, Prime Editing, and Targeted Gene Integration: Precision Therapeutic Genome Editingn
- David R. Liu, Broad Institute
- Breakthroughs in Cancer Immunotherapy: mRNA Vaccines and CAR T-Cell Advances (PANEL)
Chair: Rick Klausner, Altos Labs
- Drew Weissman, Penn Medicine
- Ira Mellman, Formelly with Genentech
- Crystal Mackal, Stanford University - Next-Generation ADCs: Challenges and Innovations in Immunotherapy Combinations (PANEL)
Chair: Sandhya Girish, Gilead
- Bin Liu, UCSF
- Strategic IP Management in Cell and Gene Therapy: Navigating Legal and Practical Challenges
- Janet Xiao, Morrison & Foerster LLP
- Advances in Allogeneic Cell Therapies: Overcoming Hurdles and Expanding Applications (PANEL)
Chair: Elliot Norry, Adaptimmune
- Larry Lamb, IN8bio
- Indu Ramachandran, Century Therapeutics - Transforming Cancer Treatment: Stem Cell and Gene Therapy Breakthroughs
Chair: Catriona Jamieson, UCSD Health
- Irv Weisman, Stanford
- Advancements and Future Directions in Therapeutic Ultrasound for Precision Medicine
Chair: Masha Stromme, EXACT Therapeutics
- Bradford Elmer, Sanofi
- John de Groot, UCSF
- Raag Airan, Stanford
