Speaker Profile
Co-Founder & President, Chai Discovery
Biography
Jack Dent is the co-founder of Chai Discovery, which is building the "computer-aided design suite" for molecules. Chai Discovery has raised $230M from leading investors including OpenAI, Thrive Capital, Anthropic, and General Catalyst. In 2025, Chai was the first company to demonstrate the ability to design antibodies on the computer with double digit success rates. Before starting Chai, Jack led engineering and product teams at Stripe. He graduated from Harvard in 2018 with a joint BA/MS in Computer Science, where his main research areas included systems and machine learning.
Session Abstract – PMWC 2027 Silicon Valley
Track Chair:
Alex Morgan, Khosla Ventures & Gad Getz, Broad Institute
PMWC Award Ceremony
• David Baker, University of Washington (Nobel Laureate, Luminary)
Featured Speakers
• David Baker, University of Washington
• Jack Dent, Chai Discovery
• Dimitri Yatsenko, DataJoint
• Evgeny Kiner, Neosplice Therapeutics
• Alex Morgan, Khosla Ventures
• Gad Getz, Broad Institute
Causal Targets, Not Just Better Molecules
Using AI and human biology to improve target selection before chemistry begins.
Data Is the Moat
What proprietary, longitudinal, and perturbational data really confer advantage.
From Prediction to Patient
Patient stratification, smarter trials, and the handoff from model to clinic.
Designed Biology Meets Drug Development
AI-designed proteins, developability, and what survives contact with reality.
The Target Discovery Bottleneck
Why splicing and other underused biology may expand what is druggable.
PMWC Hall of Impact
Previous Speakers Include
Nobel laureates, technology founders, regulators, CEOs and scientific pioneers who have taken the PMWC stage.
