Speaker Profile
Co-Founder & President, Chai Discovery
Biography
Jack Dent is the co-founder of Chai Discovery, which is building the "computer-aided design suite" for molecules. Chai Discovery has raised $230M from leading investors including OpenAI, Thrive Capital, Anthropic, and General Catalyst. In 2025, Chai was the first company to demonstrate the ability to design antibodies on the computer with double digit success rates. Before starting Chai, Jack led engineering and product teams at Stripe. He graduated from Harvard in 2018 with a joint BA/MS in Computer Science, where his main research areas included systems and machine learning.
Session Abstract – PMWC 2027 Silicon Valley
Track Chair:
Alex Morgan, Khosla Ventures and Gad Getz, Broad Institute
PMWC Award Ceremony
• Steve Wozniak, Apple
• Greg Brockman, OpenAI
Fireside Chat
• Vinod Khosla, Khosla Ventures
• Greg Brockman, OpenAI
Target Discovery: Beyond Genomics – Revealing Hidden Layers of Biology with AI
• Chair: Cindy Lawley, Olink
• Aritro Nath, City of Hope
• John Quackenbush, Harvard
• Massa Shoura, Phinomics
• Omar Serang, DNAnexus
Foundation Models of Human Cancer Biology to Predict Clinical Outcomes
• Ron Alfa, Noetik
Mechanistic Modeling of the Human Immune System: A Data-Integrated Approach to Target and Biomarker Discovery
• Liat Dassa, CytoReason
Biological Foundation Models: Harmonizing Data to Accelerate Drug Discovery
• Vitalay Fomin, Numenos
From Prediction to Translation: AI and In Vivo Validation to Improve Drug Development Success
• Gabriel Musso, BioSymetrics
Interpretable AI for Biomarker Discovery: Accelerating Drug Development and Advancing Precision Medicine
• Chair: Shivanni Kummar, PATHOMIQ
• Dale Muzzey, Myriad Genetics
• Sanoj Punnen, University of Miami
• Mark Burkard, UI
Can AI Really Create the Next Blockbuster Drug? Closing the Loop from Drug Discovery to Development
• Chair: Amar Das, Guardant Health
• Dina Katabi, Emerald/MIT
• Andrei Georgescu, Vivodyne
• James Zou, Stanford
Gemini Digital Twins Accelerate Precision Medicine
• Collin Hill, Aitia
Scaling Rare Disease Discovery with AI: From Genomic Data to Therapeutic Insights
• Lisa Gurry, GeneDx
Limited Sample Models for Faster Lead Discovery, High Accuracy, and Regulatory Grade AI
• Lalin Theverapperuma, Expert Intelligence
Enabling Targeted Precision Drug & Gene Delivery with Predictive AI
• Andre Watson, Ligandal
Is AI the New Drug or the New Therapeutic Modality
• Chair: Alex Morgan, Khosla Ventures
• Michael J. Kahana, Nia Therapeutics
• Marc Tessier-Lavigne, Xaira
• Achal Achrol, Magnus Medical
