Speaker Profile

M.D., Operating Partner, Khosla Ventures

Biography
Dr. Paz has served as an executive and board member across providers, payers, and med-tech. He was EVPCMO of CVS HealthAetna; ChancellorCEO of Ohio State Wexner Medical Center; and CEO of Penn State Health and Stony Brook Univ Medicine. He sits on the boards of Envision Healthcare and ResearchAmerica and previously served on Select Medical, USPI, Vyteris, and seven health-system boards. He advises Curai Health and previously advised Johnson Johnson and USPI. He has served on committees of the National Academy of Medicine and the National Academies. A former medical school dean and investigator in sepsis, ARDS, and medical devices, he has authored over 100 publications. Dr. Paz earned his BA and MD at the University of Rochester and an MS in life science engineering at Tufts, trained at Northwestern, and completed fellowships at Johns Hopkins in pulmonary and critical care and in environmental health sciences.


 Session Abstract – PMWC 2026 Silicon Valley


Track Co-Chairs:
- William Oh, Yale Cancer Center
- David Reese, Amgen

Patient-centric data, such as Real-World Evidence (RWE) and Real-World Data (RWD), has become critical in reshaping drug development and healthcare decision-making. Over the last few years, regulatory agencies like the FDA and EMA have increasingly embraced RWE/RWD for decision-making processes, influencing everything from new drug indications to post-marketing surveillance. The integration of RWE and RWD is not only supporting clinical trial design and regulatory approvals, but also enabling precision medicine by providing deeper insights into patient subpopulations and their outcomes

PMWC Award Ceremony Honorees
• Nigam Shah, Stanford

Keynote
• David Reese, Amgen

Keynote
• Zachary Ziegler, OpenEvidence

Real-World Evidence & Clinical AI: Closing the Loop Between Data and Care
• Chair: Roxana Daneshjou, Stanford
• Aashima Gupta, Google
• David Sontag, Layer Health
• Brigham Hyde, Atropos Health
• Brian Bradbury, Amgen

From Data to Decisions: Building Regulatory-Grade RWE from EHR Systems in Oncology
• Chair: Kate Estep, Flatiron Health

AI for Clinical Decision Support: From Models to Bedside
• Chair: Amrita Basu, UCSF
• Anurang Revri, Stanford
• Emily Alsentzer, Stanford
• Okan Ekinci, Roche

Operationalizing AI in Health Systems: Trust, Adoption & Outcomes
• Chair: Danton Samuel Char, Stanford
• Matthew Solomon, Sutter Health
• Karan Singhal, Head of Health, OpenAI
• Sina Bari, iMerit Technology
• Hal Paz, Khosla Ventures

Safe, Scalable AI in Clinical Practice: What’s Working and What’s Not
• David Entwistle, CEO, Stanford Health Care

Workflow-First Clinical AI: Integration Patterns, Guardrails & Change Management
• Jorge Duran, Klick Health

From Patient-Generated Data to Regulatory-Grade RWE: Design, Bias & Outcome Linkage
• Greg Bowyer, Evidation

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