Speaker Profile
Ph.D., CEO & Co-Founder, Allelica Inc
Biography
Giordano Botta is the Co-Founder and CEO of Allelica Inc, where he drives the development and clinical implementation of multi-ancestry polygenic risk scores (PRS). Under his leadership, Allelica pioneered the first clinical multi-ancestry PRS test for Coronary Artery Disease (CAD), breast and prostate cancer, now used by leading healthcare systems. He focuses on cost-effectiveness analysis to ensure the long-term sustainability of PRS tests. Botta has overseen the creation of a software engine and the integration of genomic and clinical data from over one million individuals of diverse ancestries to develop and validate PRS. His primary interest is advancing the integration of PRS for CAD and common cancers into standard medical care, improving prevention and early intervention strategies.
Session Abstract – PMWC 2026 Silicon Valley
Track Chair: Victor Velculescu, Johns Hopkins
PMWC Award Ceremony
• Pioneer Honoree: Klaus Pantel, UKE & ELBS
• Luminary: Rebecca Fitzgerald, University of Cambridge
Keynote
• Klaus Pantel, UKE & ELBS
Advancing Minimal Residual Disease (MRD) Detection through cfDNA and cfRNA Profiling
• Chair: Luis Diaz, MSKCC
• Anne-Renee Hartman, Adela
Early Cancer Detection / Regulatory / Population Health
• Peter Bach, DELFI Diagnostics
• Joshua J. Ofman, GRAIL
Role of AI in Liquid Biopsies and Cancer Detection
• Chair: Amoolya Singh, DELFI Diagnostics
