Speaker Profile
Ph.D., Professor, Florida State U.
Biography
Dr. Ledbetter is an internationally recognized expert in Genomics and Precision Medicine, focusing his early research efforts on discovering the genetic causes of childhood neurodevelopmental disorders, and the translation of new genomics technologies into clinically useful genetic tests for early diagnosis and intervention. He served as EVP and Founding Chief Scientific Officer at Geisinger for ten years (2010-2021), leading their ground-breaking genomics program-the first in the world to return medically actionable results to patient-participants.He held academic and leadership positions at Emory University, the University of Chicago, and Baylor College of Medicine, and is currently Professor at the Florida State University, where he is leading a new statewide pediatric genetics network funded by the State of Florida through the Sunshine Genetics Act to move whole genome sequencing into universal newborn screening for hundreds of rare diseases. He is a graduate of Tulane University and earned his Ph.D. at the University of Texas-Austin.
Session Abstract – PMWC 2026 Silicon Valley
Track Chair:
Catriona Jamieson, UCSD
Opening talk
• Catriona Jamieson, UCSD
PMWC Award Ceremony
• Judy Faulkner, Epic
• Alexis C. Komor, UCSD
What’s Next at Epic?
• Peter DeVault, Epic
Modified mRNA, siRNA, ASOs
• Chair: Alexis C. Komor, UCSD
• Niren Murthy, UC Berkeley
• Gene Yeo, UCSD
• Reuben Harris, UT Health San Antonio
Stem Cell-Targeted Therapeutics: Small Molecules & Biologics
• Chair: Catriona Jamieson, UCSD
• Irving L. Weissman, Stanford
Space-Omics & Stem-Cell Adaptation
• Chair: Catriona Jamieson, UCSD
• Alysson Muotri, UCSD
In Vivo Gene Therapies
• Chair: Gene Yeo, UCSD
• Mark A Kay, Stanford
• David Schaffer, Berkeley
Diagnostics, Prognostics, and Patient Stratification
• Chair: Ezra Cohen, Tempus
• Eitan Ruppin, NIH
• David Ledbetter, Florida State University
• Ludmil Alexandrov, UCSD
Bioprinting Transplantable Liver: mRNA-Driven Multi-Lineage Differentiation from Autologous iPSCs
• Jiwu Wang, The Scintillon Institute
A New Era in Heart Failure Treatment: Delivering on the Promise of iPSC-Derived Cardiomyocyte Therapy
• Eugene Wang, Help Therapeutics
Closing Talk
• Catriona Jamieson, UCSD
