Speaker Profile
President & CEO, Stanford Health Care
Biography
David Entwistle is the president and CEO of Stanford Health Care. He joined Stanford Health Care in July 2016 with extensive executive experience at leading academic medical centers. Entwistle is a passionate advocate of precision healthtailoring a treatment to a patients specific disease or conditionas well as prevention to empower patients to take charge of their health before they become ill.Among the factors that attracted him to Stanford Health Care are the unparalleled technologies available in Silicon Valley that help advance health care through the better application of technology for individuals. According to Entwistle, Stanford Health Care is extremely well situated to be able to apply innovative technology, such as wearable devices that track activity or monitor blood glucose levels, to improve health.Before joining Stanford Health Care, he served for nine years as CEO of the University of Utah Hospital Clinics (UUHC), the only academic medical center in the Intermountain West region. While serving at UUHC, Entwistle received the Modern Healthcare Up and Comers Award, for significant contributions in health care administration, management, or policy.He served as senior vice president and chief operating officer at the University of Wisconsin Hospital and Clinics in Madison, Wisconsin, from 20022007 and as vice president of professional services and joint venture operations at City of Hope National Medical Center in Duarte, California.As a recognized health care thought leader, Entwistle serves on the boards of the American Hospital Association, the Association of American Medical Colleges Council of Teaching Hospitals, the Accreditation Council for Graduate Medical Education, and Vizient. He is the past chair of the Utah Hospital Association and was appointed by the governor of Utah to the states Medicaid Task Force.Entwistle is an avid cyclist who enjoys both road and mountain biking, often accompanied by his teenage son. He also competes in IRONMAN Triathlons. He tweets at DEntwistleSHC.
Session Abstract – PMWC 2026 Silicon Valley
Track Co-Chairs:
- William Oh, Yale Cancer Center
- David Reese, Amgen
Patient-centric data, such as Real-World Evidence (RWE) and Real-World Data (RWD), has become critical in reshaping drug development and healthcare decision-making. Over the last few years, regulatory agencies like the FDA and EMA have increasingly embraced RWE/RWD for decision-making processes, influencing everything from new drug indications to post-marketing surveillance. The integration of RWE and RWD is not only supporting clinical trial design and regulatory approvals, but also enabling precision medicine by providing deeper insights into patient subpopulations and their outcomes
PMWC Award Ceremony Honorees
• Nigam Shah, Stanford
Keynote
• David Reese, Amgen
Keynote
• Zachary Ziegler, OpenEvidence
Real-World Evidence & Clinical AI: Closing the Loop Between Data and Care
• Chair: Roxana Daneshjou, Stanford
• Aashima Gupta, Google
• David Sontag, Layer Health
• Brigham Hyde, Atropos Health
• Brian Bradbury, Amgen
From Data to Decisions: Building Regulatory-Grade RWE from EHR Systems in Oncology
• Chair: Kate Estep, Flatiron Health
AI for Clinical Decision Support: From Models to Bedside
• Chair: Amrita Basu, UCSF
• Anurang Revri, Stanford
• Emily Alsentzer, Stanford
• Okan Ekinci, Roche
Operationalizing AI in Health Systems: Trust, Adoption & Outcomes
• Chair: Danton Samuel Char, Stanford
• Matthew Solomon, Sutter Health
• Karan Singhal, Head of Health, OpenAI
• Sina Bari, iMerit Technology
• Hal Paz, Khosla Ventures
Safe, Scalable AI in Clinical Practice: What’s Working and What’s Not
• David Entwistle, CEO, Stanford Health Care
Workflow-First Clinical AI: Integration Patterns, Guardrails & Change Management
• Jorge Duran, Klick Health
From Patient-Generated Data to Regulatory-Grade RWE: Design, Bias & Outcome Linkage
• Greg Bowyer, Evidation
