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 Speaker Profile

M.D., Ph.D., VP, Cell Biology & Translational Medicine, Kite

Biography
David Barrett joined Kite as the VP of Cell Biology in September 2022 where he serves as the lead of Translational Medicine and the Santa Monica and Philadelphia based research teams. He received a Masters in Biomedical Engineering, as well as a combined MD PhD from Virginia Commonwealth University in 2004. He went on to complete a Pediatrics Residency and Fellowship in Hematology Oncology at the Childrens Hospitalof Philadelphia in 2010 before starting his own lab as a physician scientist. During his time in the Cellular Therapyand Transplant Section at CHOP, he worked on the preclinical models for the cell therapy product that becameknown as Kymriah. Dr. Barrett cared for CAR T cell patients at CHOP from 2012-2020 and ran his lab investigatingtranslational science on CAR T trials, resulting in observations about cytokine release syndrome and the role ofmacrophages, the nature of antigen escape and the importance of juvenile cells in the pheresis and infusion products. In 2020 he left academics and joined Tmunity Therapeutics where he oversaw preclinical development andtranslational science on the solid tumor CAR T cell programs.


 Session Abstract – PMWC 2026 Silicon Valley

Track 1: Next-Gen Tx - March 4 9.00 A.M.-5.00 P.M.


Track Chair:
Priti Hegde, Kite Pharma

PMWC Award Ceremony
• Michel Sadelain, Columbia University
• Arie S. Belldegrun, Allogene Therapeutics

Keynote: Engineering the Future: Innovations in CAR-T Therapy Design
• Michel Sadelain, Columbia University

Keynote: The Industrialization of Cell Therapy:From Autologous Pioneers to Allogeneic Frontiers
• Arie S. Belldegrun, Allogene Therapeutics

Next Generation CAR-T Cell Therapies: Expanding Targets and Enhancing Designs
• Chair: David Barrett, Kite Pharma
• Carl June, University of Pennsylvania
• Michel Sadelain, Columbia University

Tumor-Infiltrating Lymphocytes (TILs): Advances and Challenges in Solid Tumors
• Chair: Allison Betof Warner, Stanford University
• George Coukos, Ludwig Institute for Cancer Research
• Max Julve, Stanford
• Stephanie Goff, NIH/NCI

Allogeneic & In Vivo Cell Therapies: Manufacturing & Clinical Progress
• Chair: Arie S. Belldegrun, Allogene Therapeutics
• Zach Roberts, Allogene Therapeutics
• Adrian Bot, Capstan Therapeutics
• Aliya Omer, AstraZeneca
• Priti Hegde, Kite Pharma

Smart Scaling: Leverating AI & Automation to De-Risk Advanced Therapy Manufacturing
• Chair: Stacie Calad-Thomson
• Samuel Rodriques, FutureHouse
• Manuel Leonetti, Biohub
• Fabian Gerlinghaus, Cellares

Designing Automated Platforms for Scalable Cell Therapy Manufacturing
• Fabian Gerlinghaus, Cellares

In-Vivo Myeloid Programming: Engineering the Innate Immune System for Solid Tumor Therapy
• Daniel Getts, Myloid Therapeutics

Operationalizing Cell & Gene Therapy Trials in a Large Health System
•Snehit Prabhu, Stanford

Gene Editing & Synthetic Biology for Therapy
• Chair: Trevor Martin, Mammoth Biosciences
• Ken Drazan, ArsenalBio
• Lynn Seely, Lyell
• Kole T. Roybal, Parker Institute
• David Kirn, 4DMT

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