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 Speaker Profile

Ph.D., Chief Executive Officer, CREATE Medicines

Biography
Daniel Getts is a global leader in RNA therapeutics and immune engineering. He is currently the founder and CEO of CREATE Medicines, a clinical-stage company focused on in vivo mRNA immune cell programming. Throughout his career, Getts has founded or co-founded several biotechnology companies, including Cour Pharmaceuticals, the field leader in immune tolerance, striking major partnerships with Takeda ($420M) and Genentech ($940M). Collectively, his ventures have generated more than $2 billion USD in value and advanced 11 novel therapies into clinical trials across cancer, autoimmune disease, and transplant rejection. Dr. Getts earned his PhD in Medicine from the University of Sydney and his MBA from Western Michigan University. He was a research professor at Northwestern University. Getts holds over 200 patents and has published extensively in top peer-reviewed journals, including Nature Biotechnology and Science Translational Medicine.


Talk
CREATE Medicines has developed an in vivo CAR platform that selectively programs T cells, NK cells, and myeloid cells directly in patients using mRNA and a targeted LNP delivery system. By eliminating complicated ex vivo cell manufacturing and patient conditioning, this approach enables scalable, off-the-shelf immunotherapies for broader patient access.


 Session Abstract – PMWC 2026 Silicon Valley

Track 1: Next-Gen Tx - March 4 9.00 A.M.-5.00 P.M.


Track Chair:
Priti Hegde, Kite Pharma

PMWC Award Ceremony
• Michel Sadelain, Columbia University
• Arie S. Belldegrun, Allogene Therapeutics

Keynote: Engineering the Future: Innovations in CAR-T Therapy Design
• Michel Sadelain, Columbia University

Keynote: The Industrialization of Cell Therapy:From Autologous Pioneers to Allogeneic Frontiers
• Arie S. Belldegrun, Allogene Therapeutics

Next Generation CAR-T Cell Therapies: Expanding Targets and Enhancing Designs
• Chair: David Barrett, Kite Pharma
• Carl June, University of Pennsylvania
• Michel Sadelain, Columbia University

Tumor-Infiltrating Lymphocytes (TILs): Advances and Challenges in Solid Tumors
• Chair: Allison Betof Warner, Stanford University
• George Coukos, Ludwig Institute for Cancer Research
• Max Julve, Stanford
• Stephanie Goff, NIH/NCI

Allogeneic & In Vivo Cell Therapies: Manufacturing & Clinical Progress
• Chair: Arie S. Belldegrun, Allogene Therapeutics
• Zach Roberts, Allogene Therapeutics
• Adrian Bot, Capstan Therapeutics
• Aliya Omer, AstraZeneca
• Priti Hegde, Kite Pharma

Smart Scaling: Leverating AI & Automation to De-Risk Advanced Therapy Manufacturing
• Chair: Stacie Calad-Thomson
• Samuel Rodriques, FutureHouse
• Manuel Leonetti, Biohub
• Fabian Gerlinghaus, Cellares

Designing Automated Platforms for Scalable Cell Therapy Manufacturing
• Fabian Gerlinghaus, Cellares

In Vivo CAR Therapy: Immune Reprogramming Directly in Patients
• Daniel Getts, Myloid Therapeutics

Operationalizing Cell & Gene Therapy Trials in a Large Health System
•Snehit Prabhu, Stanford

Gene Editing & Synthetic Biology for Therapy
• Chair: Trevor Martin, Mammoth Biosciences
• Ken Drazan, ArsenalBio
• Lynn Seely, Lyell
• Kole T. Roybal, Parker Institute
• David Kirn, 4DMT

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