Speaker Profile
Ph.D., Professor, U. of Toronto
Biography
Dr. Daniel De Carvalho is a leading cancer biologist recognized for pioneering cfDNA methylome profiling (cf MeDIP-seq), the first method to demonstrate that tumor-specific methylation patterns in plasma can reveal both the presence and tissue-of-origin of cancer. His research bridges epigenetics, liquid biopsy, and translational oncology, driving new approaches for early cancer detection, minimal residual disease detection, surveillance, classification and monitoring therapy response. At the University of Toronto and Princess Margaret Cancer Centre, his lab investigates how DNA methylation dynamics inform tumor evolution, transposable elements regulation, viral mimicry and treatment response. Dr. De Carvalho’s discoveries have reshaped how scientists and clinicians view the potential of epigenetic biomarkers in precision oncology and pioneered the use of cfDNA methylation for clinical use.
Session Abstract – PMWC 2027 Silicon Valley
Davos of Precision Medicine
PMWC 2027 Program
January 27–29, 2027 · Santa Clara Convention Center
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