Speaker Profile
M.D., Ph.D., Professor, NYU
Biography
Dan Littman, M.D., Ph.D., is the Helen L. and Martin S. Kimmel Professor of Molecular Immunology and a Professor of Cell Biology at NYU Grossman School of Medicine. His research has made fundamental contributions to understanding how T cells develop, differentiate, and respond to signals from pathogens, tissues, and the microbiome. His laboratory investigates the molecular programs that specify T-cell lineages, including regulatory and inflammatory T-cell populations, and how these programs influence immunity, autoimmunity, infection, and cancer. The group also studies how commensal microbes shape systemic immune responses and how immune mechanisms can be manipulated for therapeutic benefit. Dr. Littman’s earlier work helped define key molecules involved in T-cell recognition and HIV biology, and his research continues to connect basic immunology with questions relevant to human disease and cancer immunotherapy. He earned his M.D. and Ph.D. at Washington University in St. Louis and completed pathology training at Columbia University before establishing his independent research program.
Session Abstract – PMWC 2027 Silicon Valley
Track Chair:
Mark Genovese, Eli Lilly
PMWC Award Ceremony
• Miriam Merad, Mount Sinai (Luminary)
• Jeffrey A. Bluestone, UCSF (Luminary)
Featured Speakers
• Miriam Merad, Mount Sinai
• Jeffrey A. Bluestone, UCSF
• Gallia Levy, Gilead
• Marcela V. Maus, Harvard
• Nick Wilson, Biogen
• Megan Levings, BC Children's Hospital Research Institute
• Min Bao, Kali Therapeutics
• Purvesh Khatri, Stanford
• Heleen Scheerens, Genentech
• Pascal Geldsetzer, Stanford
• Dan Littman, NYU
• Anne Kasmar, Parexel
Macrophages Across Inflammation, Cancer & Aging
Master regulators of tissue health and disease across precision immunology.
Immune Reset in Autoimmune Disease
CAR-T, in vivo CAR, and the pursuit of durable remission.
Beyond Broad Immunosuppression
Tolerance, Tregs, and disease-modifying approaches.
Turning Biomarkers on Their Head
What we can measure before we can reliably predict response.
Precision Immunology in Clinical Development
Trial enrichment, deeper endpoints, response prediction, and regulatory strategy.
The Microbial Roots of Autoimmunity
Chronic infection, dysbiosis, and microbial signals shaping disease.
Davos of Precision Medicine
PMWC 2027 Program
January 27–29, 2027 · Santa Clara Convention Center
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PMWC is indeed The Davos of Biotech
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Previous Speakers Include
Nobel laureates, technology founders, regulators, CEOs and scientific pioneers who have taken the PMWC stage.
