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 Speaker Profile

MPH, CEO, Valo Health

Biography
Dr. Brian Alexander is Chief Executive Officer of Valo Health and a CEO Partner at Flagship Pioneering. Before joining Valo in 2024, he served as Senior Vice President of R&D at Roche/Genentech, where he helped advance the use of data science and AI in clinical development. Previously, he was CEO of Foundation Medicine, leading efforts to transform cancer care through molecular profiling and precision medicine. Brian serves on the boards of MassBio and Champions Oncology and is a co-founder of the Global Coalition for Adaptive Research, a nonprofit focused on accelerating treatments for patients with rare and deadly diseases. He previously served on the faculty of Harvard Medical School and practiced radiation oncology at Dana-Farber Cancer Institute and Brigham and Women's Hospital. He holds an MD from the University of Michigan and an MPH from Harvard, and served as a White House Fellow under Presidents George W. Bush and Barack Obama.


 Session Abstract – PMWC 2027 Silicon Valley

Track 2: AI - Jan 27 1.15 P.M.-1.30 P.M.,Track 2: AI - Jan 29 9.00 A.M.-4.30 P.M.


Track Chair:
Alex Morgan, Khosla Ventures & Gad Getz, Broad Institute

PMWC Award Ceremony
• David Baker, University of Washington (Nobel Laureate, Luminary)

Featured Speakers
• David Baker, University of Washington
• Jack Dent, Chai Discovery
• Dimitri Yatsenko, DataJoint
• Evgeny Kiner, Neosplice Therapeutics
• Alex Morgan, Khosla Ventures
• Gad Getz, Broad Institute

Causal Targets, Not Just Better Molecules
Using AI and human biology to improve target selection before chemistry begins.

Data Is the Moat
What proprietary, longitudinal, and perturbational data really confer advantage.

From Prediction to Patient
Patient stratification, smarter trials, and the handoff from model to clinic.

Designed Biology Meets Drug Development
AI-designed proteins, developability, and what survives contact with reality.

The Target Discovery Bottleneck
Why splicing and other underused biology may expand what is druggable.

Davos of Precision Medicine

PMWC 2027 Program

January 27–29, 2027 · Santa Clara Convention Center

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What the PMWC community says

In a few words.

PMWC is indeed The Davos of Biotech
Brook ByersFounderKleiner Perkins

Preparing the full agendaFive scientific tracks. Three days of discovery.

PMWC Hall of Impact

Previous Speakers Include

Nobel laureates, technology founders, regulators, CEOs and scientific pioneers who have taken the PMWC stage.

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