Speaker Profile
PMWC LUMINARY AWARD
Advanced metabolic regulation and healthy longevity from FDA approval to healthspan science
M.D., President, Kitalys Inst.
Biography
Alexander Fleming, M.D., is President and Co-Founder of the Kitalys Institute and founder and executive chairman of Kinexum, where he advises biotechnology companies on drug development and regulatory strategy. He spent 12 years at the U.S. Food and Drug Administration, serving in leadership roles overseeing metabolic and endocrine therapeutics. During that period, he helped guide reviews associated with landmark therapies including metformin, the first statin, insulin analogs, PPAR agonists, and growth hormone. Dr. Fleming has also contributed to international regulatory standards through initiatives involving FDA, the International Council for Harmonisation, and the World Health Organization. His current work focuses on healthy longevity and the interconnected metabolic drivers of chronic disease, a concept he has described as “metabesity.” He founded the Targeting Healthy Longevity conference to bring together researchers, clinicians, regulators, investors, and industry leaders working to translate aging biology and metabolic science into practical approaches for extending healthspan.
Session Abstract – PMWC 2027 Silicon Valley
Track Chair:
Nir Barzilai, Albert Einstein & Mike Snyder, Stanford
PMWC Award Ceremony
• Alexander (Zan) Fleming, Hevolution Foundation (Pioneer)
• Daniel Drucker, Sinai Health (Pioneer)
• Andrea Maier, NUS Yong Loo Lin School of Medicine (Luminary)
Featured Speakers
• Nir Barzilai, Albert Einstein
• Mike Snyder, Stanford
• Andrea Maier, NUS Yong Loo Lin School of Medicine
• Sara Espinoza, Cedars-Sinai
• Brian Kennedy, Buck Institute
• John Newman, Buck Institute / UCSF
• Marco Quarta, Rubedo Life Sciences
• Maria Dermit, Novo Nordisk
• Alan Shuldiner, Regeneron
• David Furman, Stanford
• Steve Horvath, UCLA
• Daniel Belsky, Columbia
• Ahmed Metwally, Google
• Lee Hood, Phenome Health / ISB
• George Slavich, UCLA
Targeting Aging Biology
What is actually druggable today, and what remains wishful thinking.
From Metabolism to Longevity: GLP-1 and Beyond
Incretins reshaping cardiometabolic prevention and healthy aging.
Which Aging Measures Matter?
Biological-age measures and biomarkers that can change clinical decisions.
Wearables & Digital Biomarkers at Scale
Continuous phenotyping and longitudinal signals in real-world aging.
Clinical Translation
Trials, endpoints, regulation, and the hard road to credible longevity medicine.
Davos of Precision Medicine
PMWC 2027 Program
January 27–29, 2027 · Santa Clara Convention Center
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In a few words.
PMWC is indeed The Davos of Biotech
PMWC Hall of Impact
Previous Speakers Include
Nobel laureates, technology founders, regulators, CEOs and scientific pioneers who have taken the PMWC stage.
