Speaker Profile

Ph.D., Co-Founder and CTO, OpenEvidence

Biography
Zachary Ziegler is the cofounder and CTO of OpenEvidence, the leading AI-powered medical information platform. Designed from the ground up for medical professionals, OpenEvidence organizes the worlds medical knowledge to make it more useful, open, accessible, and understandable. Launched out of the Mayo Clinic Platform Accelerate, OpenEvidence has become a critical tool in physicians tool boxes, used by over a quarter of US physicians in over 10,000 care centers across the United States. Before founding OpenEvidence, Ziegler was a PhD student at Harvard University, where he worked with Professor Sasha Rush and was awarded the National Science Foundation Graduate Research Fellowship. He completed his undergraduate studies at Cornell University, where he received the Barry Goldwater Scholarship.


 Session Abstract – PMWC 2026 Silicon Valley


Track Co-Chairs:
- William Oh, Yale Cancer Center
- David Reese, Amgen

Patient-centric data, such as Real-World Evidence (RWE) and Real-World Data (RWD), has become critical in reshaping drug development and healthcare decision-making. Over the last few years, regulatory agencies like the FDA and EMA have increasingly embraced RWE/RWD for decision-making processes, influencing everything from new drug indications to post-marketing surveillance. The integration of RWE and RWD is not only supporting clinical trial design and regulatory approvals, but also enabling precision medicine by providing deeper insights into patient subpopulations and their outcomes

Sessions:

  • TBA

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