Speaker Profile
Ph.D., Chief Technology & Business Officer, Karius
Biography
Sivan is a recognized innovator and entrepreneur in artificial intelligence who has dedicated two decades to pioneering the development of complex computational and data platforms. His key contributions include the development of novel machine-learning models tackling significant challenges in human disease. At Karius, he spearheaded the development of the foundational computational platform underlying the Karius Test, elevated the biomarker discovery program, and was central to forming and nurturing key strategic partnerships, furthering the companys impact in the medical field. Prior to Karius, Sivan was a co-founder and Chief Technology Officer at Lifecode, where he led the development of the analytical platform and validation of several clinical assays across oncology and rare diseases. He holds a Ph.D. in Computer Science from the Technion Israel Institute of Technology, and continued to Stanfords Artificial Intelligence Lab to pursue his post-doctoral research.
Session Abstract – PMWC 2026 Silicon Valley
Track Chair:
Victor Velculescu, Johns Hopkins
PMWC Award Ceremony
• Klaus Pantel, UKE & ELBS
• Daniel De Carvalho, University of Toronto
Keynote
• Klaus Pantel, UKE & ELBS
From Mutation to Methylation: The Next Wave of Liquid Biopsy Biomarkers
• Chair: Victor Velculescu, Johns Hopkins
• Daniel De Carvalho, University of Toronto
• Manel Esteller, Sant Pau Research Institute
Advancing Minimal Residual Disease (MRD) Detection through cfDNA and cfRNA Profiling
• Chair: Luis Diaz, MSKCC
• Anne-Renee Hartman, Adela
• Klaus Pantel, UKE & ELBS
AI-Informed Biomarker Trials: Turning Early Detection Signals into Clinically Actionable Designs
• Chair: Manish Kohli, University of Utah
• Luis Diaz, MSKCC
• Amoolya Singh, DELFI Diagnostics
• Peter Bach, DELFI Diagnostics
Fragmentomics for Early Detection: End Motifs and Library Prep
• Varsha Rao, Claret Bioscience
Integrating Genetic Risk with Early Detection: A Precision Prevention Framework for Cardiovascular Disease
• Giordano Botta, Allelica
Role of AI in Liquid Biopsies and Cancer Detection
• Chair: Amoolya Singh, DELFI Diagnostics
• Matthew Baker, Dxcover
