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 Speaker Profile

Ph.D., Senior Director of Translational Genetics & Data Science, Arrowhead Pharma

Biography
Shicheng Guo isSenior Director of Translational Genetics & Data Science at Arrowhead Pharmaceuticals, where I lead human-genetics-driven target discovery and biomarker strategy for RNA-based therapeutics. Dr. Guo's work sits where human data, genomics, and AI meet drug development — using population-scale biology, biobanks, and real-world evidence to power an end-to-end, AI-native discovery engine, increasingly orchestrated by agentic AI systems that reason, plan, and act across the target-to-medicine pipeline.


 Session Abstract – PMWC 2027 Silicon Valley

Track 1: Next-Gen Tx - Jan 29 9.00 A.M.-4.30 P.M.


Track Chair:
Catriona Jamieson, UCSD

Opening talk
• Catriona Jamieson, UCSD

PMWC Award Ceremony
• Judy Faulkner, Epic
• Alexis C. Komor, UCSD

What’s Next at Epic?
• Judy Faulkner, Epic
• Peter DeVault, Epic

RNA Therapeutics Beyond mRNA: siRNA, ASOs, and snRNA
• Chair: Alexis C. Komor, UCSD
• Niren Murthy, UC Berkeley
• Gene Yeo, UCSD
• Reuben Harris, UT Health San Antonio

Stem Cell-Targeted Therapeutics: Small Molecules & Biologics
• Chair: Catriona Jamieson, UCSD
• Irving L. Weissman, Stanford

Space-Omics & Stem-Cell Adaptation
• Chair: Catriona Jamieson, UCSD
• Alysson Muotri, UCSD

In Vivo Gene Therapies
• Chair: Gene Yeo, UCSD
• Mark A Kay, Stanford
• David Schaffer, UC Berkeley

Diagnostics, Prognostics, and Patient Stratification
• Chair: Ezra Cohen, Tempus
• Gudrun Stengel, Alida Biosciences
• Jarret Glasscock, Cofactor Genomics
• "Phil Febbo, Veracyte

Bioprinting Transplantable Liver: mRNA-Driven Multi-Lineage Differentiation from Autologous iPSCs
• Jiwu Wang, The Scintillon Institute

A New Era in Heart Failure Treatment: Delivering on the Promise of iPSC-Derived Cardiomyocyte Therapy
• Eugene Wang, Help Therapeutics

Closing Talk
• Catriona Jamieson, UCSD

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