Speaker Profile
Biography
Prajwal Rajappa, MD, MS, is a physician-scientist at the Cleveland Clinic who serves as the Director of Pediatric Precision Oncology and specializes in immuno-oncology. In this role, he will lead the effort across the enterprise to streamline precision oncology approaches that integrate molecular diagnostics and next-generation sequencing as an addition to the standard of care for pediatric and young adult patients with cancer. In addition, his laboratory is based in the Center for Immunotherapy and Precision Immuno-Oncology.
After obtaining his MD, Dr. Rajappa earned his Master’s Degree in Clinical and Translational Investigation at Cornell University and completed postdoctoral training with a specific focus on brain tumor immunology at Weill Cornell Medicine/New York-Presbyterian Hospital and Memorial Sloan-Kettering Cancer Center.
Prior to his recruitment to the Cleveland Clinic, Dr. Rajappa was an Associate Professor of Pediatrics and Neurological Surgery with Tenure at the Ohio State University and Principal Investigator at Nationwide Children’s Hospital.
Talk
Next‑Generation Precision Oncology for Children and Young Adults
Pediatric and adult cancers require tailored precision medicine approaches. This session discusses how real‑time genomic analysis, targeted therapies, and immuno‑oncology strategies are improving diagnostic accuracy and therapeutic decision‑making. It will highlight clinical experience, translational research progress, and the collaborative infrastructure needed to bring individualized, effective cancer treatment to children and young adults.
Clinical Dx Showcase:
Cleveland Clinic
Cleveland Clinic is a nonprofit, multispecialty academic medical center that integrates clinical care with research and education. Consistently ranked among the top hospitals in the U.S. and world, it operates a large international health system known for clinical and research excellence.
Session Abstract – PMWC 2026 Silicon Valley
The PMWC 2026 Data Applications in Clinical Diagnostics Showcase will provide a 15-30 minute time slot for selected organizations, including commercial companies, clinical testing labs, and medical research institutions, to present their latest advancements, insights, applications, and technologies to an audience of clinicians, leading investigators, academic institutions, pharma and biotech, investors, and potential clients. We will learn about new technologies and findings that promise expedited, cost-effective, and accurate clinical diagnosis for early disease detection, treatment decisions, and disease prevention.
- Clinical Dx/Oncology (including Liquid Biopsy)
- Clinical Dx/Cardio Vascular
- Clinical Dx/Neurodegenerative




