Speaker Profile
Biography
Dr. Mellios is a neuroscientist and RNA Biologist with leading expertise on circRNAs and their applications in precision medicine. He is the cofounder and CSO of Circular Genomics. He has published pivotal studies on the role of noncoding RNAs in brain function and disease and through his work at Circular Genomics has pioneered methods for the use of circRNAs for the better diagnosis and treatment of psychiatric and neurological disorders.
Clinical Dx Showcase:
Circular Genomics Inc
Circular Genomics is a pioneer in precision medicine, leveraging brain-derived circular RNA biomarkers for the better diagnosis and treatment of brain disorders. We are committed to delivering cutting-edge solutions that will revolutionize the way we diagnose and treat neurological and psychiatric illnesses.
Session Abstract – PMWC 2027 Silicon Valley
Track Chair:
David Liebeskind, UCLA
PMWC Award Ceremony
• Li-Huei Tsai, MIT Picower Institute (Pioneer)
• Thomas C. Südhof, Stanford (Nobel Laureate, Pioneer)
• David Holtzman, WashU (Pioneer)
• Henrik Zetterberg, UCL / Gothenburg (Luminary)
Featured Speakers
• Thomas C. Südhof, Stanford
• Li-Huei Tsai, MIT Picower Institute
• David Holtzman, WashU
• Henrik Zetterberg, UCL / Gothenburg
• Mark Mintun, Lilly
• Randall Bateman, WashU
• Nikolaos Mellios, Circular Genomics
• Robert Rissman, USC
• Lynn Kramer, Eisai
• Thomas F. Tropea, University of Pennsylvania
• Ari J. Green, UCSF
• Diane Chan, Mass General Brigham
• Leslie Shaw, University of Pennsylvania
• Prashanthi Vemuri, Mayo Clinic
• Kejal Kantarci, Mayo Clinic
• Dan Huddleston, Lightbox Science
• Patrick Brannelly, 10K Brains
• Allan Levey, Emory
From Blood Test to Treatment
Are we finally diagnosing Alzheimer's early enough to change care?
Precision Diagnostics Across Neurology
From biomarker to bedside across neurological disease.
Neurodegeneration Beyond Alzheimer's
Parkinson's, ALS, and FTD in the precision era.
AI & Imaging Across Neurological Disease
Precision phenotyping in stroke, epilepsy, and neurodegeneration.
Why Precision Neurology Is Not Scaling
The evidence, infrastructure, access, and workflow barriers that must be fixed.
Harnessing Brain Rhythms
Gamma oscillations, brain circuits, and the future of neurotherapy.
PMWC Hall of Impact
Previous Speakers Include
Nobel laureates, technology founders, regulators, CEOs and scientific pioneers who have taken the PMWC stage.