Nathanael S. Gray

Biography
Nathanael S. Gray, Ph.D., is the Krishnan-Shah Family Professor of Chemical and Systems Biology at Stanford University and Co-Director of Cancer Drug Discovery at Stanford Cancer Institute. A chemical biologist and medicinal chemist, he develops small molecules that probe disease biology and can serve as starting points for new therapeutics. His laboratory is particularly known for kinase inhibitor design, covalent drug discovery, targeted protein modulation, and strategies to overcome drug resistance in cancer. Earlier in his career at the Genomics Institute of the Novartis Research Foundation, Dr. Gray helped develop covalent inhibitors targeting the EGFR T790M resistance mutation, work that contributed to the scientific foundation for later-generation EGFR therapies. He subsequently built a drug-discovery program at Harvard Medical School and Dana-Farber Cancer Institute before joining Stanford in 2021. Dr. Gray earned his undergraduate and doctoral degrees at the University of California, Berkeley. His research tightly integrates synthetic chemistry, structural biology, genetics, and translational oncology to create therapeutically actionable molecules.

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