Speaker Profile
M.D., Ph.D., Assistant Professor, UTSW
Biography
Dr. Ligorio focuses on the intricate biology of human tumors. His research aims to understand the mechanisms of tumor initiation, progression, and metastasis, particularly emphasizing the role of circulating tumor cells (CTCs) and tumor microenvironments.Dr. Ligorio's postdoctoral training in the laboratory of Dr. David T. Ting, MD, at the Massachusetts General Hospital was a pivotal period. His investigations into the molecular and cellular mechanisms of cancer metastasis, particularly his groundbreaking work on the tumor-stroma interaction, have provided crucial insights into the influence of the tumor microenvironment on cancer progression and therapy resistance.In addition to his research, Dr. Ligorio is passionate about teaching and mentoring the next generation of scientists. He is actively involved in collaborating with researchers worldwide.Dr. Ligorio's contributions to cancer biology have been recognized through multiple awards and publications in high-impact scientific journals. His work continues to pave the way for novel therapeutic strategies to improve patient outcomes.
Session Abstract – PMWC 2025 Silicon Valley
Track Chair: Adrian Lee, UPMC
- PMWC Award Ceremony
Pioneer Honoree: Victor Velculescu, Johns Hopkins
Luminary Honoree: Nicola Aceto, ETH Zurich
- Keynote: Early Detection of Cancer using Cell-free DNA Fragmentomes
- Victor Velculescu, Johns Hopkins - Keynote: Circulating Tumor Cells
- Nicola Aceto, ETH Zurich - Innovative Approaches in Liquid Biopsy (PANEL)
Chair: Victor Velculescu, Johns Hopkins
- Adam Widman, MSKCC
- Improving Sensitivity of MRD and MCED - Tumor-agnostic vs. Tumor-informed ctDNA Approaches
Chair: Adrian Lee, University of Pittsburgh
- Marija Balic, UPMC
- Ola Carl Landgren, University of Miami - Sequencing Accuracy in Early Detection and MRD (PANEL)
Chair: Alex Sockell, PacBio
- James Hadfield, AstraZeneca
- Cristian Tomasetti, City of Hope
- Circulating Tumor Cells: The New Frontier (PANEL)
Chair: Nicola Aceto, ETH Zurich
- Min Yu, University of Maryland School of Medicine
- Matteo Ligorio, UTSW - Addressing Key Challenges and Questions in MCED Testing: Clinical Validation, Overdiagnosis, and Diagnostic Pathways
Chair: Tom Beer, Exact Sciences
- PMWC Showcase
- Wendy Winckler, Droplet Biosciences - Multi-Cancer Early Detection: Innovations and Real-World Evidence (PANEL)
Chair: Peter Bach, Delphi Dx
- Joshua Cohen, Haystack
- Lauren Leiman, BLOODPAC
- Josh Ofman, Grail Bio
- Tom Beer, Exact Sciences - PMWC Showcase
- Varsha Rao, Claret Bio
