Speaker Profile
PhD, President and CEO, SonALAsense
Biography
Mark has over 20 years of executive and entrepreneurial experience in the rare disease space at multiple venture backed companies. He held positions of increasing responsibility in business development (culminating as VP) at Dyax Corp, which was acquired by Shire for its FDA-approved drugs for hereditary angioedema. He has been a founder, CEO, or Executive Chair of Lotus Tissue Repair (a Third Rock Ventures company acquired by Shire), PellePharm and Molecular Skin Therapeutics (both BridgeBio companies), SeylanMed and Chromaderm (both merged into Dermbiont), NFlection Therapeutics, and Phoenicis Therapeutics. Mark is a board member of SNAPkids, a San Francisco Bay Area non-profit organization, and an advisor to the CureGM1 Foundation.
Talk
Sonodynamic Therapy: Revolutionary Non-Invasive Targeted Cancer Treatment
SonALAsense's sonodynamic therapy (SDT) is a new modality to treat cancer. It uses ultrasound to activate a drug that is selectively taken up by tumors. Clinical data shows that SDT kills brain tumor cells, regresses tumors, and extends survival without any safety concerns.
Session Abstract – PMWC 2024 Silicon Valley
Track Chair: Razelle Kurzrock, Medical College of Wisconsin
- PMWC 2024 Award Ceremony:
Luminary Honoree: Catriona Jamieson, UCSD Health
- Keynote: Targeting Cancer Stem Cells in Precision Oncology
- Catriona Jamieson, UCSD Health
- Revolutionizing Clinical Trials: Precision Oncology and Novel Trial Designs (PANEL)
Chair: Razelle Kurzrock, MCW
- Andrea Cercek, Memorial Sloan Kettering
- Apostolia Tsimberidou, MD Anderson
- Ben George, MCW
- Transcriptomics in Precision Oncology: Opportunities and Limitations (PANEL)
Chair: Razelle Kurzrock, MCW
- Andrea Califano, Columbia University
- Charles Perou, University of North Carolina
- Eytan Ruppin, NIH
- Bruce Quinn, Bruce Quinn Assoc LL
- David W. Craig, City of Hope Cancer Center - Legislation Mandating Insurance Coverage for Biomarker Testing
- Kathryn Phillips, UCSF
- Collaborative Frontiers: Transforming Cancer Care Access and Patient Outcomes (PANEL)
Chair: Maggie Rougier-Chapman, Labcorp
- Jennifer Rushton, Baptist Health System San Antonio, TX
- Rebecca Previs, Duke Cancer Institute
- Suzanne Garner, Outcomes4Me
- Taylor Jensen, Labcorp - Exploring the Clinical Utility of Dynamic ctDNA Monitoring
Chair: Lincoln Pasquina, Foundation Medicine
- Hatim Husain, UCSD - Antibody-Drug Conjugates (ADCs): Tracing the Evolution and Forecasting the Future (PANEL)
Chair: Adrian Lee, UPMC
- Sandhya Girish, Gilead
- Neelima Denduluri, Astra Zeneca
- Hope S. Rugo, UCSF - PMWC Showcase
- Michael Milburn, Genecentric Tx
- Robert Cook, Castle Bio
- Mark P. de Souza,SonALAsense, Inc.
- Amrie Grammer, Ampel Biosolutions - NCI Showcase
- Nick Reder, Alpenglow Bio
