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 Speaker Profile

M.D., Ph.D., Professor, Sant Pau Research Inst.

Biography
Dr. Esteller is an internationally recognized figure in epigenetics and oncology. His pioneering work has been instrumental in understanding how epigenetic mechanismsprocesses that regulate gene expression without altering the DNA sequenceaffect the development of cancer and other complex diseases.


 Session Abstract – PMWC 2026 Silicon Valley

Track 3: Precision Dx - March 4 9.00 A.M.-4.45 P.M.


Track Chair:
Victor Velculescu, Johns Hopkins University

PMWC Award Ceremony
• Klaus Pantel, University Medical Center Hamburg-Eppendorf / ELBS
• Daniel De Carvalho, University of Toronto

Keynote: Early Detection of Cancer by Multimodal Liquid Biopsy Analysis
• Klaus Pantel, UKE / ELBS

From Mutation to Methylation: The Next Wave of Liquid Biopsy Biomarkers
• Chair: Victor Velculescu, Johns Hopkins University
• Daniel De Carvalho, University of Toronto
• Manel Esteller, Sant Pau Research Institute
• Gordon Sanghera, Oxford Nanopore Technologies

Advancing Minimal Residual Disease Detection Through cfDNA & cfRNA Profiling
• Chair: Luis Diaz, Memorial Sloan Kettering Cancer Center
• Anne-Renee Hartman, Adela
• Klaus Pantel, UKE / ELBS

AI-Informed Biomarker Trials: Turning Early Signals into Actionable Designs
• Chair: Manish Kohli, University of Utah
• Luis Diaz, MSKCC
• Eric Klein, GRAIL
• Peter Bach, DELFI Diagnostics
• Samuel Levy, ClearNote Health

Role of AI in Liquid Biopsies & Cancer Detection
• Chair: Amoolya Singh, DELFI Diagnostics
• Matthew Baker, Dxcover
• Pankaj Vats, NVIDIA

Fragmentomics for Early Detection
• Varsha Rao, Claret Bioscience

Integrating Genetic Risk with Early Detection
• Giordano Botta, Allelica

Metagenomic Diagnostics & Global Pathogen Surveillance
• Charles Chiu, UCSF

AI-Driven Host–Pathogen Signatures from Plasma cfDNA
• Sivan Bercovici, Karius

Ultra-Sensitive Multimodal Liquid Biopsy for Early Cancer Detection
• Atul Sharan, CellMax Life

AI-Enhanced Proteomic Signatures for Early Cancer Detection
• Diana Abdueva, Aqtual

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