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 Speaker Profile

M.D., Ph.D., Professor, Sant Pau Research Inst.

Biography
Dr. Esteller is an internationally recognized figure in epigenetics and oncology. His pioneering work has been instrumental in understanding how epigenetic mechanismsprocesses that regulate gene expression without altering the DNA sequenceaffect the development of cancer and other complex diseases.The addition of Dr. Esteller strengthens IR Sant Paus critical mass of scientific talent and will drive research in areas such as applied epigenetics, translational oncology, and personalized medicine. His leadership and experience in building international networks will help attract competitive funding and top-tier researchers, positioning the center as a European benchmark in biomedical research.


 Session Abstract – PMWC 2026 Silicon Valley

Track 3: Precision Dx - March 4 9.00 A.M.-4.30 P.M.


Track Chair:
Victor Velculescu, Johns Hopkins

PMWC Award Ceremony
• Klaus Pantel, UKE & ELBS
• Daniel De Carvalho, University of Toronto

Keynote
• Klaus Pantel, UKE & ELBS

From Mutation to Methylation: The Next Wave of Liquid Biopsy Biomarkers
• Chair: Victor Velculescu, Johns Hopkins
• Daniel De Carvalho, University of Toronto
• Manel Esteller, Sant Pau Research Institute

Advancing Minimal Residual Disease (MRD) Detection through cfDNA and cfRNA Profiling
• Chair: Luis Diaz, MSKCC
• Anne-Renee Hartman, Adela
• Klaus Pantel, UKE & ELBS

AI-Informed Biomarker Trials: Turning Early Detection Signals into Clinically Actionable Designs
• Chair: Manish Kohli, University of Utah
• Luis Diaz, MSKCC
• Amoolya Singh, DELFI Diagnostics
• Peter Bach, DELFI Diagnostics

Fragmentomics for Early Detection: End Motifs and Library Prep
• Varsha Rao, Claret Bioscience

Integrating Genetic Risk with Early Detection: A Precision Prevention Framework for Cardiovascular Disease
• Giordano Botta, Allelica

Role of AI in Liquid Biopsies and Cancer Detection
• Chair: Amoolya Singh, DELFI Diagnostics
• Matthew Baker, Dxcover

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