Speaker Profile
Biography
Dr. Shaw is professor of pathology and laboratory medicine and interim director of the clinical chemistry laboratory at the University of Pennsylvania hospital and school of medicine in Philadelphia. One of his primary scientific contributions has come in the area of Alzheimer’s disease biomarker research. He developed the Alzheimer’s disease neuroimaging initiative (ADNI), which is one of the world’s largest public-private research partnerships, with more than $140 million in funding from the National Institutes of Health, pharmaceutical companies, and foundations. He currently co-directs the federally funded ADNI biomarker core laboratory at the University of Pennsylvania, as well as the Parkinson’s progression markers initiative. He has also been a pioneer in therapeutic drug monitoring. He established a toxicology and therapeutic drug monitoring laboratory at the University of Pennsylvania and participated in several international consensus panels devoted to defining best practices. He has served as president of the International Association of Therapeutic Drug Monitoring and Clinical Toxicology, served on the NCCLS committee on toxicology and drug monitoring, and was the lead editor for the first edition of the text, The Clinical Toxicology Laboratory: Contemporary Practice of Poisoning Evaluation. He has also been active in service, chairing the scientific and technical affairs committee and serving on the board of directors of the National Academy of Clinical Biochemistry. He has chaired the the Association for Diagnostics & Laboratory Medicine’s (formerly AACC) Therapeutic Drug Monitoring and Clinical Toxicology Division. Dr. Shaw has served on the boards of editors of Clinical Chemistry, Therapeutic Drug Monitoring, and Clinical Biochemistry. He has published more than 200 peer-reviewed articles on a wide variety of topics.
Session Abstract – PMWC 2027 Silicon Valley
Track Chair:
Ira Mellman, Medici Therapeutics
PMWC Award Ceremony
• Jedd D. Wolchok, Weill Cornell Medicine
• Suzanne Topalian, Johns Hopkins
• Levi Garraway, Roche
Keynote: Future Breakthroughs in Immuno-Oncology: New Targets, Modalities & Combinations
• Levi Garraway, Roche
Checkpoint 2.0 in Practice: PD-1+VEGF Wins, Resistance Salvage & Biomarker Gates
• Chair: Anne Kasmar, Parexel
• Jedd D. Wolchok, Weill Cornell Medicine
• Roy S. Herbst, Yale
• Nathan Fowler, BostonGene
Immunotherapy with Personalized Cancer Vaccines: Who, When, How Fast?
• Chair: Suzanne Topalian, Johns Hopkins
• Tal Zaks, Orbimed
• Lelia Delamarre, Genentech
The Next Era: Neutralizing On-Target, Off-Tumor Effects by Turning Cancer Against Itself
• Cyriac Roeding, Earli
Fireside Chat: Immune Tolerance to Cure, A Conversation With...
• Lee Hood, Institute for Systems Biology
• Mary E. Brunkow, Institute for Systems Biology
ADCs in the Checkpoint Era: Who Benefits, What to Combine, What to Avoid
• Chair: Shreya Badhrinarayanan, Pfizer
• Gerold Meinhardt, Daiichi Sankyo
• Vadim Koshkin, UCSF
Strategic IP Management in Cell and Gene Therapy: Navigating Legal and Practical Challenges
• Janet Xiao, Morrison & Foerster LLP
Targeting the Tumor Microenvironment (TME) in Practice: Biomarkers & Combos
• Chair: Ira Mellman, Medici Therapeutics
• Dmitry Gabrilovich, AstraZeneca
• Jennifer Mataraza, Novartis
• Nathan Fowler, BostonGene
• Christine Moussion, Genentech
Future Breakthroughs in TME Reprogramming: New Modalities, Smarter Delivery & Overcoming Resistance
• David Kirn, ReIGNITE
Radiopharmaceutical Therapy: New Targets, Isotopes, and Challenges
• Chair: William Oh, Yale
• Munir Ghesani, United Theranostics
• Sandy Srinivas, Stanford
• Anna Karmann, AdvanCell




