Speaker Profile
M.D., Professor, Yale
Biography
Kevan Herold, MD is Professor of Immunobiology and Internal Medicine at the Yale School of Medicine. His career has involved translational studies of the pathogenesis and treatment of immune diseases. He has been the PI of the clinical trials that led to the approval of teplizumab for treatment and prevention of Type 1 diabetes in addition to other immunologic and metabolic agents. His work has spanned a number of aspects of the pathogenesis of autoimmune diabetes including the immune mechanisms and the effects of autoimmunity on beta cells, with studies in preclinical and with clinical samples. His lab identified a subpopulation of beta cells that appear to resist immune attack. He developed an assay to measure β cell death in vivo and described changes in beta cells that occur in response to immunologic stressors which, he postulated may enable their survival
Session Abstract – PMWC 2027 Silicon Valley
Track Chair:
Mark Genovese, Eli Lilly
PMWC Award Ceremony
• Miriam Merad, Mount Sinai (Luminary)
• Jeffrey A. Bluestone, UCSF (Luminary)
Featured Speakers
• Miriam Merad, Mount Sinai
• Jeffrey A. Bluestone, UCSF
• Gallia Levy, Gilead
• Marcela V. Maus, Harvard
• Nick Wilson, Biogen
• Megan Levings, BC Children's Hospital Research Institute
• Min Bao, Kali Therapeutics
• Purvesh Khatri, Stanford
• Heleen Scheerens, Genentech
• Pascal Geldsetzer, Stanford
• Dan Littman, NYU
• Anne Kasmar, Parexel
Macrophages Across Inflammation, Cancer & Aging
Master regulators of tissue health and disease across precision immunology.
Immune Reset in Autoimmune Disease
CAR-T, in vivo CAR, and the pursuit of durable remission.
Beyond Broad Immunosuppression
Tolerance, Tregs, and disease-modifying approaches.
Turning Biomarkers on Their Head
What we can measure before we can reliably predict response.
Precision Immunology in Clinical Development
Trial enrichment, deeper endpoints, response prediction, and regulatory strategy.
The Microbial Roots of Autoimmunity
Chronic infection, dysbiosis, and microbial signals shaping disease.
PMWC Hall of Impact
Previous Speakers Include
Nobel laureates, technology founders, regulators, CEOs and scientific pioneers who have taken the PMWC stage.
