Speaker Profile
Ph.D., CEO, GeneScape
Biography
Dr. Karen E. Malone brings a strong combination of translational medicine and biomarker expertise, grounded in a clear commercial perspective, to drive science-based business programs. With over 15 years of industry experience across both CRO and pharmaceutical environments, she has progressed into senior, strategy-focused roles with increasing responsibility. Her work centers on new product planning and corporate strategy, with a particular emphasis on the rapidly evolving, high-technology field of rare disease therapeutics and diagnostics.
Talk
Diagnostic Integrity for Medically Actionable Inherited Diseases
GeneScape is developing the most advanced genetic diagnostic algorithms for inherited rare diseases to facilitate therapeutic development and bring potentially life changing therapies to the patients. Based on large-scale, diverse genomic datasets and proprietary expertly-curated patient databases, coupled with important strategic partnerships, GeneScape is poised to bring state-of-the-art, disease-specific diagnostic algorithms to global labs.
Genomic Profiling Showcase:
GeneScape
GeneScape currently offers services for precision medicine epidemiology focusing on genetically defined diseases. We have compiled a suite of unique data resources, including proprietary data, that we are now leveraging to develop specialized algorithms for genetic diagnosis in rare diseases to improve accuracy.
Session Abstract – PMWC 2026 Silicon Valley
The PMWC 2026 Genomic Profiling Showcase will provide a 15-30 min speaking opportunity for selected companies working with the latest technologies in nucleic acid sequencing such as NGS, providing instrumentation for genomic sequencing, and offering direct to consumer services. These companies will share their innovative products and services to an audience of leading investors, potential clients and partners. The Genomic Profiling Showcase will exhibit the latest innovations in methods and instruments used for DNA/ RNA sequencing to ascertain the genomic and transcriptional profile of a person in order to understand why some people get certain diseases while others do not, or why people react in different ways to the same drug. This information is also being used to develop new ways to diagnose, treat, and prevent diseases, such as cancer.
