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 Speaker Profile

Head of Health AI, OpenAI

Biography
Karan Singhal is a leading researcher in artificial intelligence, specializing in the intersection of AI and healthcare. He currently heads the Health AI team at OpenAI, where he focuses on developing large language models (LLMs) that aim to make medical expertise universally accessible and ensure safety in high-stakes health applications.Before joining OpenAI, Singhal was instrumental in the development of Med-PaLM and Med-PaLM 2 at Google, AI models designed for medical question answering. These models were integrated into Google Cloud and received recognition in prominent publications such as Nature, Scientific American, The Economist, and the BBC.


 Session Abstract – PMWC 2026 Silicon Valley

Track 2: AI - March 5 9.00 A.M.-4.45 P.M.


Track Chairs:
William Oh, Yale & David Reese, Amgen

PMWC Award Ceremony
• Nigam Shah, Stanford

Keynote
• David Reese, Amgen

Real-World Evidence & Clinical AI: Closing the Loop Between Data and Care
• Chair: Roxana Daneshjou, Stanford
• Aashima Gupta, Google
• David Sontag, Layer Health
• Brigham Hyde, Atropos Health
• Michael Pfeffer, Stanford
• Thomas Fuchs, Lilly

From Data to Decisions: Building Regulatory-Grade RWE from EHR Systems in Oncology
• Chair: Kate Estep, Flatiron Health

AI and Real-World Evidence: Building a Learning Health System for Precision Care
• Rich Gliklich, OM1

AI for Clinical Decision Support: From Models to Bedside
• Chair: Amrita Basu, UCSF
• Anurang Revri, Stanford
• Emily Alsentzer, Stanford
• Okan Ekinci, Roche

AI for CDS: From Models to Bedside
• Zachary Ziegler, OpenEvidence

Operationalizing AI in Health Systems: Trust, Adoption & Outcomes
• Chair: Danton Samuel Char, Stanford
• Matthew Solomon, Sutter Health
• Karan Singhal, Head of Health, OpenAI
• Sina Bari, iMerit Technology
• Hal Paz, Khosla Ventures

Safe, Scalable AI in Clinical Practice: What’s Working and What’s Not
• Chair: Nigam Shah, Stanford
• David Entwistle, CEO, Stanford Health Care
• Vincent Liu, Kaiser Permanente

AI for Precision Psychiatry: Integrating Multimodal Data Into Clinical Decision Support
• Erwin Estigarribia, HEADLAMP Health

Workflow-First Clinical AI: Integration Patterns, Guardrails & Change Management
• Jorge Duran, Klick Health

From Patient-Generated Data to Regulatory-Grade RWE: Design, Bias & Outcome Linkage
• Greg Bowyer, Evidation

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