Speaker Profile
Ph.D., Distinguished Professor Emeritus of Metabolism and Endocrinology, UCSF
Biography
Dr. Jeff Bluestone is a Distinguished Emeritus Professor in the Diabetes Center at
UCSF and a managing director of Vie Ventures. He served in various other roles over 25
years at UCSF, including as a member of the faculty, Founding Director of the Diabetes Center,
and Executive Vice Chancellor and Provost. He is an international leader in the field of
immunotherapy and has published more than 500 papers focused on understanding the basic
processes that control T-cell activation and immune tolerance in autoimmunity, organ
transplantation and cancer. His research has led to the development of the first FDA-approved
drug that delays/prevents autoimmune Type 1 diabetes and the first FDA-approved checkpoint
inhibitor for the treatment of metastatic melanoma and other cancers. Dr. Bluestone was the
Founding Director of the Immune Tolerance Network and the Founding CEO of the Parker
Institute for Cancer Immunotherapy. Dr. Bluestone is a member of the National Academy of
Science, National Academy of Medicine, and American Academy of Arts and Sciences.
Session Abstract – PMWC 2027 Silicon Valley
Track Chair:
Mark Genovese, Eli Lilly
PMWC Award Ceremony
• Miriam Merad, Mount Sinai (Luminary)
• Jeffrey A. Bluestone, UCSF (Luminary)
Featured Speakers
• Miriam Merad, Mount Sinai
• Jeffrey A. Bluestone, UCSF
• Gallia Levy, Gilead
• Marcela V. Maus, Harvard
• Nick Wilson, Biogen
• Megan Levings, BC Children's Hospital Research Institute
• Min Bao, Kali Therapeutics
• Purvesh Khatri, Stanford
• Heleen Scheerens, Genentech
• Pascal Geldsetzer, Stanford
• Dan Littman, NYU
• Anne Kasmar, Parexel
Macrophages Across Inflammation, Cancer & Aging
Master regulators of tissue health and disease across precision immunology.
Immune Reset in Autoimmune Disease
CAR-T, in vivo CAR, and the pursuit of durable remission.
Beyond Broad Immunosuppression
Tolerance, Tregs, and disease-modifying approaches.
Turning Biomarkers on Their Head
What we can measure before we can reliably predict response.
Precision Immunology in Clinical Development
Trial enrichment, deeper endpoints, response prediction, and regulatory strategy.
The Microbial Roots of Autoimmunity
Chronic infection, dysbiosis, and microbial signals shaping disease.
PMWC Hall of Impact
Previous Speakers Include
Nobel laureates, technology founders, regulators, CEOs and scientific pioneers who have taken the PMWC stage.
