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 Speaker Profile

PMWC PIONEER AWARD
Drove checkpoint blockade into practice (incl. ipilimumab)

M.D., Ph.D., PHARMD, FAACR, FAIO, FASCO, Director, Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine

Biography
Jedd is a clinician-scientist exploring innovative immunotherapeutic strategies in laboratory models, and a principal investigator in numerous pivotal clinical trials. Dr. Wolchok helped establish immunotherapy as a standard approach to cancer treatment and was instrumental in the clinical development leading to the approval of ipilimumab and the combination of nivolumab and ipilimumab for advanced melanoma. He supervises an NIH R01-funded basic science laboratory that is focused on investigating novel immunotherapeutic agents in pre-clinical laboratory models. The focus of his translational research laboratory is to investigate innovative means to modulate the immune response to cancer as well as to better understand the mechanistic basis for sensitivity and resistance to currently available immunotherapies. Dr. Wolchok received his BA degree from Princeton University, and his MS, PhD and MD degrees from New York University.


Talk
Clinical uses of cancer immunotherapy
We will explore innovative immunotherapeutic strategies to modulate the immune response to cancer as well as to better understand the mechanistic basis for sensitivity and resistance to currently available immunotherapies.


 Session Abstract – PMWC 2026 Silicon Valley

Track 1: Next-Gen Tx - March 5 9.00 A.M.-5.00 P.M.


Track Chair:
Ira Mellman, Medici Therapeutics

PMWC Award Ceremony
• Jedd D. Wolchok, Weill Cornell Medicine
• Suzanne Topalian, Johns Hopkins
• Levi Garraway, Roche

Targeting the Tumor Microenvironment (TME) in Practice: Biomarkers & Combos
• Chair: Ira Mellman, Medici Therapeutics
• Dmitry Gabrilovich, AstraZeneca
• Shannon Turley, Amgen

Immunotherapy with Personalized Cancer Vaccines: Who, When, How Fast?
• Chair: Suzanne Topalian, Johns Hopkins
• Tal Zaks, Orbimed
• Lelia Delamarre, Genentech

Fireside Chat: Immune Tolerance to Cure, A Conversation With...
• Mary E. Brunkow, Institute for Systems Biology
• Lee Hood, Institute for Systems Biology

ADCs in the Checkpoint Era: Who Benefits, What to Combine, What to Avoid
• Chair: Shreya Badhrinarayanan, Pfizer
• S. Peter Kang, Daiichi Sankyo
• Vadim Koshkin, UCSF

Strategic IP Management in Cell and Gene Therapy: Navigating Legal and Practical Challenges
• Janet Xiao, Morrison & Foerster LLP

Checkpoint 2.0 in Practice: PD-1+VEGF Wins, Resistance Salvage & Biomarker Gates
• Chair: Anne Kasmar, Parexel
• Jedd D. Wolchok, Weill Cornell Medicine
• Roy S. Herbst, Yale

Radiopharmaceutical Therapy: New Targets, Isotopes, and Challenges
• Chair: William Oh, Yale
• Munir Ghesanim, United Theranostics
• Sandy Srinivas, Stanford
• Anna Karmann, AdvanCell

Future Breakthroughs in Immuno-Oncology: New Targets, Modalities & Combinations
• Chair: Levi Garraway, Roche

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