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 Speaker Profile

PMWC PIONEER AWARD

M.D., EVP R&D, Amgen

Biography
Dr. James "Jay" Bradner is executive vice president, Research and Development. He is responsible for advancing Amgen's pipeline, which includes potential first-in-class or best-in-class medicines in all stages of development across the company's four therapeutic areas of focus: oncology, inflammation, general medicine and rare disease, in addition to biosimilars. He is also responsible for Amgen's worldwide research efforts. Prior to joining Amgen, Dr. Bradner served as President of the Novartis Institutes for BioMedical Research, where he was a member of the Executive Committee of Novartis. His research and leadership have contributed to numerous development programs, multiple investigational new drug applications and positive proof-of-concept studies in clinical investigation. He also has been a clinician at the Dana-Farber Cancer Institute and an associate professor at Harvard Medical School. As an entrepreneur, he co-founded and built several biotechnology startups. Additionally, he has co-authored dozens of scientific publications and is a named inventor on numerous U.S. patent applications. Dr. Bradner is a graduate of Harvard College and the University of Chicago Medical School. He completed his residency in Medicine at Brigham & Women's Hospital, his fellowship in Medical Oncology and Hematology at the Dana-Farber Harvard Cancer Center, and his postdoctoral training in Chemistry and Chemical Biology at Harvard University.


 Session Abstract – PMWC 2027 Silicon Valley

Track 1: Next-Gen Tx - Jan 29 9.00 A.M.-4.30 P.M.


Track Chair:
Catriona Jamieson, UCSD

Opening talk
• Catriona Jamieson, UCSD

PMWC Award Ceremony
• Judy Faulkner, Epic
• Alexis C. Komor, UCSD

What’s Next at Epic?
• Judy Faulkner, Epic
• Peter DeVault, Epic

RNA Therapeutics Beyond mRNA: siRNA, ASOs, and snRNA
• Chair: Alexis C. Komor, UCSD
• Niren Murthy, UC Berkeley
• Gene Yeo, UCSD
• Reuben Harris, UT Health San Antonio

Stem Cell-Targeted Therapeutics: Small Molecules & Biologics
• Chair: Catriona Jamieson, UCSD
• Irving L. Weissman, Stanford

Space-Omics & Stem-Cell Adaptation
• Chair: Catriona Jamieson, UCSD
• Alysson Muotri, UCSD

In Vivo Gene Therapies
• Chair: Gene Yeo, UCSD
• Mark A Kay, Stanford
• David Schaffer, UC Berkeley

Diagnostics, Prognostics, and Patient Stratification
• Chair: Ezra Cohen, Tempus
• Gudrun Stengel, Alida Biosciences
• Jarret Glasscock, Cofactor Genomics
• "Phil Febbo, Veracyte

Bioprinting Transplantable Liver: mRNA-Driven Multi-Lineage Differentiation from Autologous iPSCs
• Jiwu Wang, The Scintillon Institute

A New Era in Heart Failure Treatment: Delivering on the Promise of iPSC-Derived Cardiomyocyte Therapy
• Eugene Wang, Help Therapeutics

Closing Talk
• Catriona Jamieson, UCSD

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