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 Speaker Profile

PMWC LUMINARY AWARD

M.D., Frederick L. Locke, MD Department Chair and Senior Member, Blood and Marrow Transplant and Cellular Immunotherapy Program Leader, Cellular Immunotherapy, Moffitt Medical Group Program Leader, Immuno-Oncology Program, Moffitt Research Institute, Moffitt Cancer Ctr.

Biography
Frederick L. Locke, MD, is a physician-scientist whose work has helped shape the development and safe delivery of CAR T-cell therapy worldwide. As a leader of the pivotal clinical trials that established CAR T-cell therapy as a standard treatment for lymphoma, including ZUMA-1 and ZUMA-7, he has helped define the field's understanding and management of its potentially life-threatening toxicities. Through collaborations spanning academia, industry, professional societies, and treatment centers, Dr. Locke has helped develop the evidence, standards, and best practices that have enabled cellular therapies to safely reach patients around the world.


Talk
Pending
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 Session Abstract – PMWC 2027 Silicon Valley

Track 1: Next-Gen Tx - Jan 27 9.00 A.M.-5.00 P.M.


Track Chair:
Priti Hegde, Kite Pharma

PMWC Award Ceremony
• Arie S. Belldegrun, Allogene Therapeutics

Keynote: The Industrialization of Cell Therapy:From Autologous Pioneers to Allogeneic Frontiers
• Arie S. Belldegrun, Allogene Therapeutics

Next Generation CAR-T Cell Therapies: Expanding Targets and Enhancing Designs
• Chair: Erin Harris Cell & Gene
• David Barrett, Kite Pharma
• Carl June, University of Pennsylvania
• Michel Sadelain, Columbia University

PMWC Award Ceremony
• Michel Sadelain, Columbia University
Keynote: Engineering the Future: Innovations in CAR-T Therapy Design
• Michel Sadelain, Columbia University

Tumor-Infiltrating Lymphocytes (TILs): Advances and Challenges in Solid Tumors
• Chair: Allison Betof Warner, Stanford University
• George Coukos, Ludwig Institute for Cancer Research
• Max Julve, Stanford
• Stephanie Goff, NIH/NCI

Allogeneic & In Vivo Cell Therapies: Manufacturing & Clinical Progress
• Chair: Arie S. Belldegrun, Allogene Therapeutics
• Zach Roberts, Allogene Therapeutics
• Adrian Bot, Capstan Therapeutics
• Priti Hegde, Kite Pharma

Smart Scaling: Leverating AI & Automation to De-Risk Advanced Therapy Manufacturing
• Chair: Stacie Calad-Thomson
• Samuel Rodriques, FutureHouse
• Manuel Leonetti, Biohub
• Fabian Gerlinghaus, Cellares

Designing Automated Platforms for Scalable Cell Therapy Manufacturing
• Fabian Gerlinghaus, Cellares

In Vivo CAR Therapy: Immune Reprogramming Directly in Patients
• Daniel Getts, Myloid Therapeutics

Operationalizing Cell & Gene Therapy Trials in a Large Health System
•Snehit Prabhu, Stanford

Gene Editing & Synthetic Biology for Therapy
• Chair: Trevor Martin, Mammoth Biosciences
• Ken Drazan, ArsenalBio
• Lynn Seely, Lyell
• Kole T. Roybal, Parker Institute
• David Kirn, 4DMT

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PMWC 2027 Jan. 27-29 • Santa Clara
15 tracks • 400 speakers Co-hosted by Stanford/UCSF/Yale • Davos of PM
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