Speaker Profile
Distinguished Scientist, GRAIL
Biography
Eric A. Klein is a Distinguished Scientist at GRAIL. Previously he served as the Andrew C. Novick Distinguished Professor and Chair of the Glickman Urological and Kidney Institute and Lerner College of Medicine of the Cleveland Clinic, where he was also a member of the Department of Cancer Biology of the Cleveland Clinic Lerner Research Institute, the Taussig Cancer Institute, and the Genitourinary Malignancies Program in the Case Comprehensive Cancer Center. Dr. Kleins clinical and research interests focused on prostate cancer with an emphasis on genomics and clinical trials. Most recently his work has focused on the clinical development of multicancer early detection tests. Dr. Klein was a Fellow in the Distinguished Careers Institute at Stanford University in 2022 and joined GRAIL in 2023.
Session Abstract – PMWC 2026 Silicon Valley
Track Chair:
Victor Velculescu, Johns Hopkins
PMWC Award Ceremony
• Klaus Pantel, UKE & ELBS
• Daniel De Carvalho, University of Toronto
Keynote
• Klaus Pantel, UKE & ELBS
From Mutation to Methylation: The Next Wave of Liquid Biopsy Biomarkers
• Chair: Victor Velculescu, Johns Hopkins
• Daniel De Carvalho, University of Toronto
• Manel Esteller, Sant Pau Research Institute
Advancing Minimal Residual Disease (MRD) Detection through cfDNA and cfRNA Profiling
• Chair: Luis Diaz, MSKCC
• Anne-Renee Hartman, Adela
• Klaus Pantel, UKE & ELBS
AI-Informed Biomarker Trials: Turning Early Detection Signals into Clinically Actionable Designs
• Chair: Manish Kohli, University of Utah
• Luis Diaz, MSKCC
• Amoolya Singh, DELFI Diagnostics
• Peter Bach, DELFI Diagnostics
Fragmentomics for Early Detection: End Motifs and Library Prep
• Varsha Rao, Claret Bioscience
Integrating Genetic Risk with Early Detection: A Precision Prevention Framework for Cardiovascular Disease
• Giordano Botta, Allelica
Role of AI in Liquid Biopsies and Cancer Detection
• Chair: Amoolya Singh, DELFI Diagnostics
• Matthew Baker, Dxcover
