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 Speaker Profile

Ph.D., Co-Founder & Scientific Advisor, Singular Genomics

Biography
Eli Glezer co-founded Singular Genomics and led the RD and Engineering teams in the development of NGS and Spatial Sequencing technology. Today, the G4X Spatial Sequencer brings the power of high-speed in-situ sequencing to spatial biology, offering unrivaled throughput for spatial analysis of gene transcripts and proteins in real-world FFPE tissue samples. This technology is enabling next-generation pathology, revealing new biological insights in clinical studies and translational medicine. Prior to Singular, Dr. Glezer served as CTO at Meso Scale Diagnostics where he led the development of a market-leading multiplexed immunoassay technology, used today in thousands of laboratories word-wide. Eli's interdisciplinary work at the intersection of biology, chemistry, physics and engineering has resulted in a wide range of inventions, reflected in 75 issued US patents. He received his BA degrees in Physics and Mechanical Engineering from UC Berkeley, and a PhD in Applied Physics from Harvard University.


Talk
Spatial Sequencing for Next Generation Pathology
Imaging RNA and proteins in tissue with sub-cellular resolution brings new molecular-level insights to pathology. The G4X Spatial Sequencer uses NGS with 4-color, high-speed, sub-micron-resolution imaging to analyze gene transcripts and proteins in FFPE tissue sections. Processing up to 40 samplesrun (1 cm2 each), the G4X enables large-scale clinical studies for next generation pathology.


 Session Abstract – PMWC 2026 Silicon Valley

Track 3: Precision Dx - March 6 9.00 A.M.-4.15 P.M.


Track Chair:
Christina Curtis, Stanford

PMWC Award Ceremony
• W.E. Moerner, Stanford
• Serge Saxonov, 10x Genomics
• Priscilla Chan, Biohub

Honoree Fireside
• Christina Curtis, Stanford
• Priscilla Chan, Biohub

Honoree Fireside: From Measurement to Meaning: What Data AI Still Needs in Biology
• Christina Curtis, Stanford
• W.E. Moerner, Stanford
• Serge Saxonov, 10x Genomics

Unraveling Tissue Architecture with Single-Cell & Spatial Multi-Omics
• Chair: Garry P. Nolan, Stanford
• Joakim Lundeberg, SciLifeLab
• Tae Hyun Hwang, Vanderbilt University Medical Center
• Michael Angelo, Stanford

Spatial Sequencing for Next Generation Pathology
• Eli Glezer, Singular Genomics

Precision Profiling of Cells: Insights from Imaging-Spectral Flow Cytometry and Single-Cell Multiomics
• Aruna Ayer, BD

Single-Cell Genotype and Targeted Gene Expression Assay
• Zivjena Vucetic, Mission Bio

Resolving Cellular Lineage and State in Tumors with High-Resolution Single-Cell Genomics
• Gary Schroth, Cellanome

From Cellular State to Disease Gene Prediction at Population Scale
• Kyle Farh, Illumina

Tumor Evolution & Clonal Dynamics: From Models to Monitoring
• Christina Curtis, Stanford

Personal Omics at Scale: What Longitudinal Profiles Add to Early Detection
• Michael Snyder, Stanford

Multi-Omics-Driven Early Detection: Beyond Liquid Biopsy
• Chair: Alex Aravanis, Moonwalk Biosciences
• Ash Alizadeh, Stanford
• Sara Ahadi, OmicsEra

AI in Molecular Diagnostics: Integrating Multi-Omics & Clinical Data
• Chair: Marina Sirota, UCSF
• Olivier Gevaert, Stanford
• Rebecca Critchley-Thorne, Castle Biosciences
• Lihua Jiang, Stanford
• Yunguan Wang, Cincinnati Children's

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