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 Speaker Profile

Ph.D., Professor, Director, UC Berkeley

Biography
David Schaffer is the Hubbard Howe Professor at the University of California, Berkeley, and he also serves as the Director of QB3, Bakar Labs, and the Bakar Fellows Program. He completed his B.S. in chemical engineering at Stanford University in 1993, his Ph.D. in chemical engineering at MIT in 1998, and a postdoctoral fellowship at the Salk Institute for Biological Studies in 1999 before joining Berkeley in 1999. There, he applies engineering principles to optimize gene and stem cell therapies, work that includes developing the concept of applying directed evolution to engineer targeted and efficient viral gene therapy vectors as well as new technologies to investigate and control stem cell function. In addition, he has also co-founded seven companies from his lab that have advanced technologies into 10 human clinical trials. Finally, has received numerous recognitions including being elected to the National Academy of Engineering and National Academy of Inventors.


 Session Abstract – PMWC 2026 Silicon Valley


Track Chair:
Cindy Perettie, EVP Kite Pharma
PMWC Award Ceremony
• Michel Sadelain, Columbia
• Arie S. Belldegrun, Allogene Therapeutics

Keynote: Engineering the Future: Innovations in CAR-T Therapy Design
• Michel Sadelain, Columbia

CAR-T Cell Therapies: Strategies in Mitigating Challenges in Solid Tumor Delivery
• Chair: David Barrett, Kite
• Carl June, University of Pennsylvania
• Michel Sadelain, Columbia

Tumor-Infiltrating Lymphocytes (TILs): Advances and Challenges in Solid Tumors
• Chair: Allison Betof Warner, Stanford
• George Coukos, Ludwig Institute for Cancer Research
• Max Julve, Royal Marsden
• Stephanie Goff, NIH/NCI

Allogeneic & In Vivo Cell Therapies: Manufacturing & Clinical Progress
• Chair: Arie S. Belldegrun, Allogene Therapeutics
• David Chang, Allogene Therapeutics
• Adrian Bot, Capstan Therapeutics
• Aliya Omer, AstraZeneca
• Priti Hegde, Kite Pharma

Designing Automated Platforms for Scalable Cell Therapy Manufacturing
Fabian Gerlinghaus (Cellares)

TCR-Based Cell Therapies: New Targets and Clinical Advances
• Chair: Diwakar Davar, UPMC
• Lauren Harshman, Clasp Therapeutics
• Cassian Yee, MD Anderson

Gene Editing & Synthetic Biology for Therapy
• Chair: Matthew Porteus, Stanford
• Rachel Haurwitz, Caribou Biosciences
• Kole T. Roybal, Parker Institute
• Ken Drazan, ArsenalBio

Synthetic Circuits for Smarter Cell Therapies: Enhancing NK Precision and Persistence
Gudrun Stengel, Alida BioSciences

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