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 Speaker Profile

M.D.,Ph.D., Director, Sanford Stem Cell Institute, UCSD Health

Biography
Catriona Jamieson is a leading physician scientist who has specialized inmyeloproliferative neoplasms (MP Ns) and leukemia. She discoveredmissplicing, RNA hyperediting, and splice isoform switching as mechanismsgoverning human cancer stem cell maintenance in selective niches. Thesediscoveries have helped to shed light on the underlying mechanisms of cancer and have opened up new avenues for targeted therapies. Dr. Jamieson's contributions to the field of precision medicine include herpivotal role in the rescue and development of the JAK inhibitor fedratinibfor the treatment of myelofibrosis. Additionally, she is known for herunwavering dedication to advancing innovative therapies and her outst and ingleadership as the director of the Sanford Stem Cell Institute at UCSD andas a co-founder of Impact Biosciences and Aspera Biomedicines.


 Session Abstract – PMWC 2027 Silicon Valley

Track 1: Next-Gen Tx - Jan 29 9.00 A.M.-4.30 P.M.


Track Chair:
Catriona Jamieson, UC San Diego

PMWC Award Ceremony
• Emmanuelle Charpentier, Max Planck (J. Craig Venter Visionary Award · Nobel Laureate)
• Jay Bradner, Amgen (Pioneer)
• Adrian Krainer, Cold Spring Harbor Laboratory (Luminary)
• Randy Schekman, UC Berkeley (Nobel Laureate, Pioneer)

Featured Speakers
• Emmanuelle Charpentier, Max Planck
• Randy Schekman, UC Berkeley
• Jay Bradner, Amgen
• Adrian Krainer, Cold Spring Harbor Laboratory
• Alexis C. Komor, UC San Diego
• Nicole Gaudelli, GV
• Rachel Haurwitz, Caribou Bio
• Gene Yeo, UC San Diego
• Timothy Yu, Boston Children's / Harvard
• Shicheng Guo, Arrowhead Pharmaceuticals
• Mark A. Kay, Stanford
• Niren Murthy, UC Berkeley
• Ben Deverman, Broad Institute
• Stanley Crooke, n-Lorem / Ionis

Programming Protein Fate
Molecular glues, degraders, and induced proximity crossing into medicines.

Genome Editing Beyond the First Wave
Base, prime, and CRISPR-enabled editing moving from correction to clinic.

RNA Editing, Splice Modulation & Programmable RNA
RNA editing, ASOs, and splice modulation with chemistry already reaching patients.

In Vivo Delivery & Vector Engineering
AAV, LNP, and next-generation vectors that decide what is treatable.

From N-of-1 to Platform
Evidence, CMC, regulation, and access for individualized genetic medicines.

PMWC 2027 Silicon Valley - Program

PMWC Hall of Impact

Previous Speakers Include

Nobel laureates, technology founders, regulators, CEOs and scientific pioneers who have taken the PMWC stage.

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PMWC 2027 Jan. 27-29 • Santa Clara
15 tracks • 400 speakers Co-hosted by Stanford/UCSF/Yale • Davos of PM
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